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Mount Sinai researchers present landmark studies at AATS meeting

Icahn School of Medicine at Mount Sinai researchers presented several landmark studies at the 2015 American Association for Thoracic Surgery meeting in Seattle.

5 May 2015

Max Planck Institute researchers find protein profiles of DNA repair

During each cell division, more than 3.3 billion base pairs of genomic DNA have to be duplicated and segregated accurately to daughter cells. But what happens when the DNA template is damaged in such a way that the replication machinery gets stuck? To answer this question, scientists in the team of Matthias Mann at the Max Planck Institute of Biochemistry in Martinsried near Munich, with colleagues in Copenhagen and at Harvard, have analyzed how the protein composition of the DNA replication machinery changes upon encountering damaged DNA.

5 May 2015

Caregiver's behavior influences oral health habits in children

Studies have long associated low-income areas with poor oral health. But dental researchers at Case Western Reserve University and University of Washington sensed that other factors related to income may be at work -- in particular, education level.

5 May 2015

Green tea compound, voluntary exercise slow Alzheimer's disease progression in mice

According to the National Institutes of Health, Alzheimer's disease (AD) may affect as many as 5.5 million Americans. Scientists currently are seeking treatments and therapies found in common foods that will help stave off the disease or prevent it completely.

5 May 2015

Study could provide new approaches to treating meniscal injuries

Within the knee, two specialized, C-shaped pads of tissue called menisci perform many functions that are critical to knee-joint health. The menisci, best known as the shock absorbers in the knee, help disperse pressure, reduce friction and nourish the knee.

5 May 2015

Mutations in PARN and RTEL1 associated with familial pulmonary fibrosis, telomere shortening

Researchers at UT Southwestern Medical Center have identified mutations in two genes that cause a fatal lung scarring disease known as familial pulmonary fibrosis.

5 May 2015

AIDS patients at increased risk of developing intermediate-stage AMD

Patients with acquired immunodeficiency syndrome (AIDS) have a four-fold increase in their risk of developing intermediate-stage age-related macular degeneration (AMD) compared to people of the same age who are not infected with HIV, according to results from the Longitudinal Study of the Ocular Complications of AIDS (LSOCA) presented today at the 2015 ARVO Annual Meeting in Denver, CO.

5 May 2015

Family, neighborhood environments affect mental health outcomes in children

A team of researchers from Sweden and the United States have examined the potential role of the family environment and neighborhood factors on mental health outcomes in a new study published in Journal of Psychiatric Research.

5 May 2015

IQWiG finds minor added benefit of dulaglutide in combination with short-acting insulin for type 2 diabetes

Since 2014 dulaglutide has been approved alone or in combination with other drugs for the treatment of adults with type 2 diabetes. The German Institute for Quality and Efficiency in Health Care examined in a dossier assessment whether this new drug offers an added benefit over the appropriate comparator therapies.

5 May 2015

University of Adelaide research shows that doping decreases athletes' performances

Doping is damaging the image of sport without benefitting athletes' results, according to University of Adelaide research.

5 May 2015

Researchers reveal potential mode of drug resistance in malaria parasites

Scientists have uncovered a potential mode of parasite drug resistance in malaria infection, according to a report published in The Journal of Experimental Medicine.

5 May 2015

Exposure to traffic-related air pollution during infancy increases risk of developing allergies

New research from the Canadian Healthy Infant Longitudinal Development (CHILD) study shows that exposure to outdoor air pollution during the first year of life increases the risk of developing allergies to food, mould, pets and pests.

5 May 2015

Eribulin from marine sponge inhibits replication of breast cancer cells

For more than three decades a new drug for the treatment of breast cancer had not been presented. A group of researchers were given the task of analyzing a marine sponge called Halichondrin okadai and obtained a mesylate eribulin substance that had already been applied to patients with this disease in the stage of metastasis, ie, when the disease spreads to other body parts and the result was that it inhibited tumor growth.

4 May 2015

Frederick Alt honored with 2015 Szent-Györgyi Prize for Progress in Cancer Research

Frederick Alt, PhD, director of the Program in Cellular and Molecular Medicine at Boston Children's Hospital, has been honored with the 2015 Szent-Györgyi Prize for Progress in Cancer Research.

4 May 2015

Researchers suggest ways to keep harmful tobacco and alcohol products away from young people

As the realities of legalized marijuana take hold in four states and the District of Columbia, legislators and regulators could learn a lot from the successes -- and failures -- of the tobacco and alcohol industries in keeping their harmful products out of the hands of children and adolescents.

4 May 2015

No evidence for cancer risk with growth hormone therapy

There is no evidence that growth hormone (GH) therapy increases the likelihood of neoplasms in children with no additional risk factors, says the Pediatric Endocrine Society Drug and Therapeutics Committee.

1 May 2015

New approach to vaccine development is 97 per cent efficacious and could eliminate shingles

A new vaccine has proven almost completely effective in preventing shingles (disease medical name: herpes zoster), an extremely painful nerve infection which affects a third of Australians; most over the age of 50.

1 May 2015

Predominant first Alzheimer’s symptoms vary with diagnosis age

The symptoms presented by patients newly diagnosed with Alzheimer’s disease vary with age, with younger patients less likely to have initial memory problems, research shows.

30 Apr 2015

Texas Biomed scientists awarded NIH grant to develop potential HPV-based HIV vaccine

Scientists at Texas Biomedical Research Institute have begun work on a nearly $3.4 million study funded by the National Institutes of Health over the next four years to create an attenuated, or weakened, virus that is a hybrid of the papilloma virus and the human immunodeficiency virus, with the potential to jumpstart a body's immune response to develop antibodies against both viruses.

30 Apr 2015

New research-based pharmaceutical industry report provides insights on how to slow down antimicrobial resistance (AMR) and boost antibiotic R&D

Eleven IFPMA member companies are involved in the development of new antibiotics. There are currently 34 antibacterial compounds in development (19 molecules and 15 vaccines). Eight compounds are undergoing the final stages of demonstrating their efficacy, quality, and safety (phase 3 clinical trials)...

30 Apr 2015

Research News and Research

Mount Sinai researchers present landmark studies at AATS meeting

Max Planck Institute researchers find protein profiles of DNA repair

Caregiver's behavior influences oral health habits in children

Green tea compound, voluntary exercise slow Alzheimer's disease progression in mice

Study could provide new approaches to treating meniscal injuries

Mutations in PARN and RTEL1 associated with familial pulmonary fibrosis, telomere shortening

AIDS patients at increased risk of developing intermediate-stage AMD

Family, neighborhood environments affect mental health outcomes in children

IQWiG finds minor added benefit of dulaglutide in combination with short-acting insulin for type 2 diabetes

University of Adelaide research shows that doping decreases athletes' performances

Researchers reveal potential mode of drug resistance in malaria parasites

Exposure to traffic-related air pollution during infancy increases risk of developing allergies

Eribulin from marine sponge inhibits replication of breast cancer cells

Frederick Alt honored with 2015 Szent-Györgyi Prize for Progress in Cancer Research

Researchers suggest ways to keep harmful tobacco and alcohol products away from young people

No evidence for cancer risk with growth hormone therapy

New approach to vaccine development is 97 per cent efficacious and could eliminate shingles

Predominant first Alzheimer’s symptoms vary with diagnosis age

Texas Biomed scientists awarded NIH grant to develop potential HPV-based HIV vaccine

New research-based pharmaceutical industry report provides insights on how to slow down antimicrobial resistance (AMR) and boost antibiotic R&D

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