B Cell News and Research

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SARS-CoV-2 3CLpro also susceptible to mutations

Researchers assess the activity of all potential mutations in the SARS-CoV-2 3CLpro.

29 Jun 2022

Study provides a framework for understanding how tissue-resident memory T cells adapt to distinct environments

Scientists exploring how our immune system responds to pathogens and cancers have ramped up their attention to CD8+ T cells, which are deployed in response to infections and malignancies and equipped to remember the identities of malicious invaders.

29 Jun 2022

Existing cancer drug shows promise for treating patients with muscular dystrophy

Researchers at the University of British Columbia's School of Biomedical Engineering have discovered that an existing cancer drug could have potential as a treatment for muscular dystrophy.

29 Jun 2022

Online version of algorithm shows how biases in RNA sequences affect gene expression

A recent publication from researchers at the University of Kentucky explains the importance of identifying and understanding how differences between tissues and cells alter gene expression without changing the underlying genetic code.

29 Jun 2022

Discovery suggests a new way to slow or stop metastatic spread of pancreatic cancer

Pancreatic cancer, though rare, is one of the deadliest of cancers, killing nearly 50,000 people yearly and doing so quickly, primarily because it metastasizes rapidly through the body. Barely one in 10 people survive beyond five years.

29 Jun 2022

Researchers explore disease severity post-infection with SARS-CoV-2 Omicron in hematologic patients

A new study has studied the clinical outcome and spectrum in 61 patients infected with the SARS-CoV-2 Omicron variant.

29 Jun 2022

Epigenome-wide DNA methylation patterns in convalescent COVID-19 subjects

Researchers investigated the epigenetic rewiring of odor perception in SARS-CoV-2-infected cells.

29 Jun 2022

Study finds SARS-CoV-2 E protein antagonizes BET protein-mediated antiviral responses during infection

Researchers assessed the impact of SARS-CoV-2 envelope protein on the bromodomain and extraterminal domain (BET) proteins.

29 Jun 2022

New robotic AI system can autonomously determine the optimal conditions for growing replacement retina

A joint research group led by Genki Kanda at the RIKEN Center for Biosystems Dynamics Research (BDR) has developed a robotic artificial intelligence (AI) system for autonomously determining the optimal conditions for growing replacement retina layers necessary for vision.

29 Jun 2022

Immune particles from llama blood could offer protection against several COVID-19 variants

Mount Sinai-led researchers have shown that tiny, robust immune particles derived from the blood of a llama could provide strong protection against every COVID-19 variant, including Omicron, and 18 similar viruses including SARS-CoV-2 and SARS-CoV-1, which was responsible for the 2003 SARS outbreak.

29 Jun 2022

Complex molecular dance could inform the development of future treatments for fragile X syndrome

Like many neurological diseases, there's a lot we don't understand about fragile X syndrome. But, after studying the disorder for several years, Lynne Maquat's lab knew two important things: the enzyme AKT, which plays a key role in cell growth and survival, and the quality control pathway known as NMD (nonsense-mediated mRNA decay), are both in overdrive in fragile X.

29 Jun 2022

Investigating the prerequisites for developing RNA-based antibiotics

In the fight against the Covid-19 pandemic, mRNA-based vaccines have impressively demonstrated their potential. Using this technology, scientists were able to rapidly develop and bring to market vaccines against SARS-CoV-2 that have been extremely effective at protecting millions of people against severe disease progression of COVID-19 or even death.

29 Jun 2022

Study focuses on how telomerase activity affects the regenerative potential of stem cells in human urine

The Wake Forest Institute for Regenerative Medicine researchers who were the first to identify that stem cells in human urine have potential for tissue regenerative effects, continue their investigation into the power of these cells.

28 Jun 2022

Memory B cells can be localized in the lungs, research shows

How can we increase the efficacy of vaccines used to protect against viral respiratory diseases such as influenza and COVID-19? Scientists from Inserm, CNRS and Aix-Marseille Université at the Center of Immunology Marseille-Luminy are opening up new prospects in the field, with the triggering of memory B cells directly in the lungs looking to be a promising avenue.

28 Jun 2022

New study looks at the role of beta cells in triggering autoimmunity

Research into the causes of type 1 diabetes often focuses on the autoimmune response, where the immune system destroys pancreatic islet beta cells that produce insulin.

28 Jun 2022

Analysis finds variation in the management of mantle cell lymphoma across clinical settings

There is considerable variation in the management of mantle cell lymphoma across different clinical settings, and some strategies do not always conform with what might be expected, according to an analysis by investigators from Weill Cornell Medicine and other leading health institutions.

28 Jun 2022

Potent antibody with a novel neutralization mechanism against SARS-CoV-2 variants

In a recent study posted to the bioRxiv* pre-print server, researchers in the United States described a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal antibody (mAb) SP1-77 that broadly neutralized its multiple variants of concern (VOCs).

28 Jun 2022

UMass Amherst assistant professor wins $1.4 million grant to engineer synthetic bacteria for water contaminant removal

Lauren Andrews, University of Massachusetts Amherst assistant professor and the Marvin and Eva Schlanger Faculty Fellow in the department of chemical engineering, has received a three-year, $1.4 million grant from the National Science Foundation for a collaborative project to engineer synthetic bacteria to neutralize toxic contaminants found in drinking water.

28 Jun 2022

Scientists define plasma dose for future cancer treatments

Chinese researchers may have found a new approach to treat cancer by using a plasma treatment to induce apoptosis, the death of cancer cells, without any obvious side effect to normal cells.

28 Jun 2022

Duke researchers identify role for key gene in developmental disability syndrome

A single gene that was previously found to be the driving force in a rare syndrome linked to epilepsy, autism and developmental disability has been identified as a linchpin in the formation of healthy neurons.

28 Jun 2022

B Cell News and Research

SARS-CoV-2 3CLpro also susceptible to mutations

Study provides a framework for understanding how tissue-resident memory T cells adapt to distinct environments

Existing cancer drug shows promise for treating patients with muscular dystrophy

Online version of algorithm shows how biases in RNA sequences affect gene expression

Discovery suggests a new way to slow or stop metastatic spread of pancreatic cancer

Researchers explore disease severity post-infection with SARS-CoV-2 Omicron in hematologic patients

Epigenome-wide DNA methylation patterns in convalescent COVID-19 subjects

Study finds SARS-CoV-2 E protein antagonizes BET protein-mediated antiviral responses during infection

New robotic AI system can autonomously determine the optimal conditions for growing replacement retina

Immune particles from llama blood could offer protection against several COVID-19 variants

Complex molecular dance could inform the development of future treatments for fragile X syndrome

Investigating the prerequisites for developing RNA-based antibiotics

Study focuses on how telomerase activity affects the regenerative potential of stem cells in human urine

Memory B cells can be localized in the lungs, research shows

New study looks at the role of beta cells in triggering autoimmunity

Analysis finds variation in the management of mantle cell lymphoma across clinical settings

Potent antibody with a novel neutralization mechanism against SARS-CoV-2 variants

UMass Amherst assistant professor wins $1.4 million grant to engineer synthetic bacteria for water contaminant removal

Scientists define plasma dose for future cancer treatments

Duke researchers identify role for key gene in developmental disability syndrome

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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