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Research shows how exercise helps improve brain health

Physical activity is frequently cited as a means of improving physical and mental health. Researchers at the Beckman Institute for Advanced Science and Technology have shown that it may also improve brain health more directly.

19 Apr 2023

Unlocking the potential of RNA lipid nanoparticles to revolutionize cancer treatment

This paper discusses the use of RNA lipid nanoparticles for cancer immunotherapy, which has shown promising results in clinical use. However, only a small percentage of patients respond to existing immunotherapies, and the paper explores opportunities for improvement.

18 Apr 2023

Study reveals DCAF1 protein's role in colon cancer development through EZH2 phosphorylation

A recent study reveals that DCAF1 is overexpressed and phosphorylates EZH2 in colon cancer cells.

18 Apr 2023

New DCFHP-alum COVID-19 vaccine candidate shows durable, broad-spectrum protection in non-human primates

The newly developed DCFHP-alum COVID-19 vaccine candidate is affordable and effective for mass vaccination.

18 Apr 2023

Dietary dicarbonyls may improve insulin sensitivity and reduce type 2 diabetes risk

A recent study investigates how dietary intake of dicarbonyls impacts insulin sensitivity and β-cell function and, as a result, the incidence of type 2 diabetes.

18 Apr 2023

Cocktail of IgG3 antibodies could have a potent clinical effect against SARS-CoV-2

Is it possible to improve the antibodies that the body produces to fight SARS-CoV2? In a study led by researchers from Lund University in Sweden, this was investigated by redesigning antibodies and combining them against the virus.

18 Apr 2023

U-M researcher launches new project to identify the full range of RNA building blocks inside human cells

University of Michigan pediatric neurologist Vivian Cheung is launching an international project to identify the full range of RNA building blocks inside human cells.

18 Apr 2023

Rapamycin and other rapalogs have potential to delay cancer

A new research perspective was published in Oncotarget's Volume 14 on April 14, 2023, entitled, "Cancer prevention with rapamycin."

18 Apr 2023

SWOG investigators report results from DART clinical trial of immunotherapy combination for rare gynecologic cancers

Results from the S1609 DART clinical trial, which tested an immunotherapy combination of ipilimumab plus nivolumab in 53 cohorts of patients with rare cancers, are being reported for five cohorts of patients who had rare gynecologic cancers.

18 Apr 2023

Researchers discover the molecule responsible for guiding T cells toward tumors

Immunotherapy, particularly CAR T-Cell treatment for cancer, is extending the lives of many patients. But sometimes the therapy randomly migrates to places it shouldn't go, tucking into the lungs or other noncancerous tissue and causing toxic side effects.

18 Apr 2023

Precise genome editing approach can correct mutation that causes sickle cell disease

Scientists at St. Jude Children’s Research Hospital and the Broad Institute of MIT and Harvard showed how prime editing can correct the mutation that causes sickle cell disease in a potentially curative approach.

18 Apr 2023

Latest single cell technology identifies cell types related to CAD pathogenesis

A new study from the University of Eastern Finland identified 12 different cell types involved in the pathogenesis of coronary artery disease, CAD. The researchers also showed that the genetic risk factors for CAD take their effect especially via smooth vascular muscle cells, which change their phenotype as the disease progresses.

18 Apr 2023

Researchers reveal how a new CALM mutation causes deadly arrhythmias

Arrhythmia, when left unchecked, can be life-threatening.

18 Apr 2023

Ecological and evolutionary implications of the sharing of metabolites between different microbes in the gut microbiome

The researchers provide important insights into the cross-feeding mechanisms of nutrients in the gut microbiome and their impacts on host health.

18 Apr 2023

Understanding human mycobiome commensalism and pathogenesis

Researchers explored commensalism and pathogenesis relationships in the human mycobiome.

18 Apr 2023

Is there a correlation between acute and chronic red wine intake and health?

Researchers examined the correlations between acute and chronic red wine (RW) intake and health.

18 Apr 2023

Edible mushrooms: the role of antioxidant compounds as potential candidates for neurodegenerative disease prevention and treatment

Researchers evaluated whether edible mushrooms aid in preventing neurodegenerative diseases.

18 Apr 2023

Unravelling the factors influencing host tropism of SARS-CoV-2-related bat coronaviruses

Researchers investigated the tropism of SC2r-CoVs infecting Rhinolophus bats.

18 Apr 2023

New study aims to elucidate the role of p21 in chronic lung inflammation

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 7, entitled, "p21 facilitates chronic lung inflammation via epithelial and endothelial cells."

18 Apr 2023

Tissue-resident memory cells are key to immunity to Salmonella in mice

Salmonella infections cause about a million deaths a year worldwide, and there is an urgent need for better vaccines for both typhoid fever and non-typhoidal Salmonella disease.

18 Apr 2023

Cell News and Research

Research shows how exercise helps improve brain health

Unlocking the potential of RNA lipid nanoparticles to revolutionize cancer treatment

Study reveals DCAF1 protein's role in colon cancer development through EZH2 phosphorylation

New DCFHP-alum COVID-19 vaccine candidate shows durable, broad-spectrum protection in non-human primates

Dietary dicarbonyls may improve insulin sensitivity and reduce type 2 diabetes risk

Cocktail of IgG3 antibodies could have a potent clinical effect against SARS-CoV-2

U-M researcher launches new project to identify the full range of RNA building blocks inside human cells

Rapamycin and other rapalogs have potential to delay cancer

SWOG investigators report results from DART clinical trial of immunotherapy combination for rare gynecologic cancers

Researchers discover the molecule responsible for guiding T cells toward tumors

Precise genome editing approach can correct mutation that causes sickle cell disease

Latest single cell technology identifies cell types related to CAD pathogenesis

Researchers reveal how a new CALM mutation causes deadly arrhythmias

Ecological and evolutionary implications of the sharing of metabolites between different microbes in the gut microbiome

Understanding human mycobiome commensalism and pathogenesis

Is there a correlation between acute and chronic red wine intake and health?

Edible mushrooms: the role of antioxidant compounds as potential candidates for neurodegenerative disease prevention and treatment

Unravelling the factors influencing host tropism of SARS-CoV-2-related bat coronaviruses

New study aims to elucidate the role of p21 in chronic lung inflammation

Tissue-resident memory cells are key to immunity to Salmonella in mice

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo