Animal Model News and Research

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Ground-breaking discovery offers new hope for treatment of Alzheimer’s, other neurological diseases

There is new hope for the treatment of Alzheimer’s and other neurological diseases following a ground-breaking discovery made by an Australian-Chinese research collaboration.

10 Aug 2018

Novel discovery offers hope for treatment of Alzheimer's and other neurological diseases

There is new hope for the treatment of Alzheimer's and other neurological diseases following a ground-breaking discovery made by an Australian-Chinese research collaboration.

10 Aug 2018

Researchers uncover clues on how the brain separates important from unimportant information

The precise interaction of brain waves and nerve cells may be decisive for the amazing ability of our brain to separate important from unimportant information, even when we are flooded with stimuli.

9 Aug 2018

Nanostructured sensor system offers active monitoring of brain aneurysm treatment

Implantation of a stent-like flow diverter can offer one option for less invasive treatment of brain aneurysms – bulges in blood vessels – but the procedure requires frequent monitoring while the vessels heal.

2 Aug 2018

Catalytic nanoparticles can effectively prevent tooth decay

Combine a diet high in sugar with poor oral hygiene habits and dental cavities, or caries, will likely result.

1 Aug 2018

Mutations of IRF2BPL gene associated with previously undiagnosed neurological disorder

An international team of scientists, including researchers from Baylor College of Medicine, has discovered mutations of gene IRF2BPL that are associated with a previously undiagnosed neurological disorder in seven unrelated individuals.

27 Jul 2018

Researchers find that IgM antibody could protect against HIV-1

A team of scientists from Texas Biomedical Research Institute have homed in on an antibody that could protect against infection with HIV-1.

24 Jul 2018

Study reveals protective potential of new class of antibodies against HIV-1 infection

A group of scientists at Texas Biomedical Research Institute have zeroed in on a new defense against HIV-1, the virus that causes AIDS. Led by Ruth Ruprecht, M.D., Ph.D., the team used an animal model to show for the first time that an antibody called Immunoglobulin M was effective in preventing infection after mucosal AIDS virus exposure.

24 Jul 2018

Novel delivery system for bacteriophages could offer new way to battle lung infections

A new delivery system for bacteriophages - viruses that selectively attack harmful bacteria - could help give doctors a new way to battle lung infections that threaten older patients and people with cystic fibrosis.

17 Jul 2018

Researchers describe key role of enzyme in regulating immune response against Chagas disease parasite

In an article published recently in the journal Nature Communications, researchers affiliated with the University of São Paulo in Brazil describe the central role played by an enzyme called phosphatidylinositol 3-kinase gamma in regulating the immune response against Trypanosoma cruzi, the protozoan parasite that causes Chagas disease.

16 Jul 2018

New drug strategy can alleviate multiple behavioral, cellular deficiencies in FXS mouse model

Research in mice shows that a pharmacological strategy can alleviate multiple behavioral and cellular deficiencies in a mouse model of fragile X syndrome, the most common inherited form of intellectual disability and a major single-gene cause of autism spectrum disorders.

13 Jul 2018

Sodium nitroprusside treatment prevents schizophrenia symptoms in animal model

Researchers at the Federal University of São Paulo in Brazil have tested a treatment with sodium nitroprusside in a strain of rats that spontaneously develop some of the symptoms associated with schizophrenia.

12 Jul 2018

Researchers use genome editing to reduce cholesterol levels in animal model

Using genome editing to inactivate a protein called PCSK9 effectively reduces cholesterol levels in rhesus macaques, a species of monkey, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

10 Jul 2018

Study identifies constellation of metabolites linked to ME/CFS

A study led by researchers at the Center for Infection and Immunity at Columbia University's Mailman School of Public Health has identified a constellation of metabolites related to myalgic encephalomyelitis/chronic fatigue syndrome.

10 Jul 2018

Researchers use gene therapy to cure obesity and type 2 diabetes in mice

A research team from the UAB led by Professor Fatima Bosch has managed to cure obesity and type 2 diabetes in mice using gene therapy.

9 Jul 2018

Researchers focus on mechanisms involved in development of non-alcoholic fatty liver disease

One of the lines of research of the UPV/EHU's Lipids & Liver group, which focusses on the mechanisms involved in the development and progression of non-alcoholic fatty liver disease, is achieving significant advances in a range of aspects; these include the identification of proteins that alter the metabolic pathways in the development and progression of liver disease, and even cancer, and the seeking of targets to enable the disease to be reversed.

9 Jul 2018

Animal Model News and Research

Ground-breaking discovery offers new hope for treatment of Alzheimer’s, other neurological diseases

Novel discovery offers hope for treatment of Alzheimer's and other neurological diseases

Researchers uncover clues on how the brain separates important from unimportant information

Nanostructured sensor system offers active monitoring of brain aneurysm treatment

Catalytic nanoparticles can effectively prevent tooth decay

Mutations of IRF2BPL gene associated with previously undiagnosed neurological disorder

Researchers find that IgM antibody could protect against HIV-1

Study reveals protective potential of new class of antibodies against HIV-1 infection

Novel delivery system for bacteriophages could offer new way to battle lung infections

Researchers describe key role of enzyme in regulating immune response against Chagas disease parasite

New drug strategy can alleviate multiple behavioral, cellular deficiencies in FXS mouse model

Sodium nitroprusside treatment prevents schizophrenia symptoms in animal model

Researchers use genome editing to reduce cholesterol levels in animal model

Study identifies constellation of metabolites linked to ME/CFS

Researchers use gene therapy to cure obesity and type 2 diabetes in mice

Researchers focus on mechanisms involved in development of non-alcoholic fatty liver disease

New mouse model could shed light on autism subtype

Study describes new mechanism involved in memory loss associated with aging

Study links molecular changes in the brain to key behaviors in addiction

Review: Stem cells appear to help fight obesity in animal models

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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