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Impact of vaping high CBD/low THC products on driving ability

Researchers assess how cannabinoid levels in the blood affect driving after single or repetitive vaporization of cannabis rich in CBD.

31 Aug 2023

Can muvalaplin achieve safe and tolerable plasma concentrations adequate to reduce steady-state Lp(a) levels without modulating plasminogen activity in humans?

Researchers evaluated the tolerability, safety, pharmacodynamics, and pharmacokinetic properties of muvalaplin.

30 Aug 2023

ARAMIS trial finds no benefit of anakinra in acute myocarditis

The largest randomized controlled trial of patients with acute myocarditis has found that anakinra is safe but does not reduce complications. The late breaking research presented in a Hot Line session today at ESC Congress 2023.

29 Aug 2023

Extended P2Y12 inhibitor monotherapy reduces bleeding and ischemic events in ACS patients

Extended P2Y12 inhibitor monotherapy beyond 12 months after percutaneous coronary intervention (PCI) reduces bleeding and ischemic events in acute coronary syndrome (ACS) patients at high risk for both types of events.

29 Aug 2023

Anticoagulation after primary PCI does not prevent adverse outcomes in STEMI patients

Anticoagulation after primary percutaneous coronary intervention (PCI) does not prevent adverse outcomes in patients with ST-segment elevation myocardial infarction (STEMI), according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

29 Aug 2023

SGLT2 inhibitors do not reduce 28-day mortality in hospitalized COVID-19 patients

Sodium glucose co-transporter-2 (SGLT2) inhibitors do not lead to lower 28-day all-cause mortality compared with usual care or placebo in patients hospitalized with COVID-19, according to late-breaking research presented in a Hot Line session today at ESC Congress 2023.

29 Aug 2023

Inorganic nitrate reduces contrast-induced nephropathy in high-risk patients

Inorganic nitrate reduces contrast-induced nephropathy (CIN), improves renal outcomes and reduces cardiac events compared to placebo in patients at risk of renal injury undergoing coronary angiography for acute coronary syndrome, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

29 Aug 2023

Analysis reveals limited evidence on use of cannabis products in children with cancer

A recent analysis of all relevant published studies reveals a lack of evidence to determine the dosing, safety, and efficacy of medical marijuana or cannabis-containing products for managing symptoms experienced by children with cancer.

29 Aug 2023

Acoramidis shows potential to be effective, safe treatment for transthyretin amyloid cardiomyopathy

Acoramidis improves outcomes in patients with transthyretin amyloid cardiomyopathy (ATTR-CM) compared with placebo, according to late-breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Intravenous ferric carboxymaltose linked to lower risk of heart failure hospitalizations in iron-deficient patients

In iron-deficient patients with heart failure and reduced or mildly reduced left ventricular ejection fraction, intravenous ferric carboxymaltose (FCM) is associated with a reduced risk of the composite outcome of total cardiovascular hospitalization and cardiovascular death through 52 weeks compared with placebo, according to late-breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Study shows benefit of traditional Chinese medicine for heart failure

The traditional Chinese medicine qiliqiangxin reduces hospitalization for heart failure and cardiovascular death in patients with heart failure and a reduced ejection fraction (HFrEF), according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

UAB researchers show beneficial effect of verapamil for patients with Type 1 diabetes

In 2012, University of Alabama at Birmingham researcher Anath Shalev, M.D., reported that a decades-old blood pressure medication called verapamil completely reversed diabetes in animal models.

25 Aug 2023

NOAH-AFNET 6 trial: Oral anticoagulation not recommended for patients with atrial high rate episodes

Blood thinners (anticoagulants) cause bleeding without preventing stroke in patients with atrial high rate episodes (AHRE), but without electrocardiogram (ECG)-diagnosed atrial fibrillation, according to late breaking research presented in a Hot Line session today at ESC Congress 2023 and simultaneously published in the New England Journal of Medicine.

25 Aug 2023

Colchicine does not reduce perioperative AF or MINS in major non-cardiac thoracic surgery

Colchicine does not significantly reduce perioperative atrial fibrillation (AF) or myocardial injury after non-cardiac surgery (MINS) in patients undergoing major non-cardiac thoracic surgery, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

25 Aug 2023

Semaglutide could be a game-changer for patients with HFpEF and obesity

Semaglutide improves heart failure-related symptoms and physical function and results in greater weight loss compared with placebo in patients with heart failure with preserved ejection fraction (HFpEF) and obesity, according to late-breaking research presented in a Hot Line session today at ESC Congress 2023.

25 Aug 2023

New drug could transform treatment of brain tumors in younger people

A top UVA Health cancer expert is highlighting how a new drug could transform how doctors treat a brain tumor that typically strikes younger people.

25 Aug 2023

New targeted therapy zolbetuximab extends survival for patients with advanced gastric cancer

An international phase 3 clinical trial, done in participation with Weill Cornell Medicine and NewYork-Presbyterian, found that a new targeted treatment called zolbetuximab, given in combination with a standard chemotherapy, extended survival for patients with advanced gastric or gastroesophageal junction cancer that overexpressed a specific biomarker.

23 Aug 2023

$9.57 million grant will support a clinical trial to study new treatment option for NAFLD

According to the National Institutes of Health, approximately 24% of adults in the United States have nonalcoholic fatty liver disease (NAFLD), an umbrella term for a range of liver conditions affecting people who drink little to no alcohol that can lead to cirrhosis, liver cancer and liver failure.

23 Aug 2023

CPAP therapy can mitigate telomere shortening in sleep apnea patients

Obstructive sleep apnea (OSA) consists of multiple episodes of partial or complete closure of the upper airway that occur during sleep, leading to breathing cessation lasting more than ten seconds and sometimes even several minutes, followed by arousals and deep breathing.

23 Aug 2023

Strep A infections on the rise among Australians, study finds

Australia has experienced an intense surge in severe Strep A cases, similar to the northern hemisphere wave, despite differences in seasons and circulating respiratory viruses, according to a new study.

22 Aug 2023

Placebo News and Research

Impact of vaping high CBD/low THC products on driving ability

Can muvalaplin achieve safe and tolerable plasma concentrations adequate to reduce steady-state Lp(a) levels without modulating plasminogen activity in humans?

ARAMIS trial finds no benefit of anakinra in acute myocarditis

Extended P2Y12 inhibitor monotherapy reduces bleeding and ischemic events in ACS patients

Anticoagulation after primary PCI does not prevent adverse outcomes in STEMI patients

SGLT2 inhibitors do not reduce 28-day mortality in hospitalized COVID-19 patients

Inorganic nitrate reduces contrast-induced nephropathy in high-risk patients

Analysis reveals limited evidence on use of cannabis products in children with cancer

Acoramidis shows potential to be effective, safe treatment for transthyretin amyloid cardiomyopathy

Intravenous ferric carboxymaltose linked to lower risk of heart failure hospitalizations in iron-deficient patients

Study shows benefit of traditional Chinese medicine for heart failure

UAB researchers show beneficial effect of verapamil for patients with Type 1 diabetes

NOAH-AFNET 6 trial: Oral anticoagulation not recommended for patients with atrial high rate episodes

Colchicine does not reduce perioperative AF or MINS in major non-cardiac thoracic surgery

Semaglutide could be a game-changer for patients with HFpEF and obesity

New drug could transform treatment of brain tumors in younger people

New targeted therapy zolbetuximab extends survival for patients with advanced gastric cancer

$9.57 million grant will support a clinical trial to study new treatment option for NAFLD

CPAP therapy can mitigate telomere shortening in sleep apnea patients

Strep A infections on the rise among Australians, study finds

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