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Rhesus monkeys and cats potential spillover reservoirs for COVID-19 virus

A team of researchers from Switzerland, Costa Rica and Germany has conducted a study showing which animal species could potentially serve as spillback reservoirs of severe acute repertory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

12 Nov 2020

Researchers discover a mechanism that cells use to degrade microRNAs

UT Southwestern researchers have discovered a mechanism that cells use to degrade microRNAs (miRNAs), genetic molecules that regulate the amounts of proteins in cells.

12 Nov 2020

Return of mice to home cage evokes significant rise in dopamine release, shows study

By monitoring a well-replicated biomarker associated with reward, a study by neuroscientists from Florida Atlantic University provides evidence that the old adage, "There's no place like home," has its roots deep in the brain.

12 Nov 2020

Nursing homes still see dangerously long waits for COVID test results

Nursing homes are still taking days to get back COVID-19 test results as many shun the Trump administration's central strategy to limit the spread of the virus among old and sick Americans.

12 Nov 2020

TMDU and Fujitsu complete cancer gene network analysis in less than a day

Tokyo Medical and Dental University and Fujitsu Laboratories Limited have recently completed, in less than a day, estimation of the network that represents the influence relationship between genes and prediction of their relationship with infiltration and metastasis based on genes highly likely to be involved in cancer development.

12 Nov 2020

Men and women may require different brain tumor therapy, study finds

The current study shows that the sex differences in the tumor phenotype vary with the effect of the enhancer regulatory molecule bound to Brd4 on the course of stem cell-like differentiation in male and female GBM cells. Inhibition of Brd4 by genetic and pharmacological factors also varies in males and females, both in vivo and in vitro.

11 Nov 2020

Comparison of 240 mammal genomes helps geneticists to identify disease mutations

A large international consortium led by scientists at Uppsala University and the Broad Institute of MIT and Harvard has sequenced the genome of 130 mammals and analyzed the data together with 110 existing genomes to allow scientist to identify which are the important positions in the DNA.

11 Nov 2020

Researchers uncover potential genetic target for treating endometriosis

Michigan State University researchers have identified a potential genetic target for treating an especially painful and invasive form of endometriosis.

11 Nov 2020

Spike-based DNA vaccine shows excellent protection against SARS-CoV-2 in a hamster model

A study conducted at the United States Army Research Institute of Infectious Diseases shows how a relatively simple full-length DNA vaccine against spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can elicit neutralizing antibody response in an animal model – even after a single shot with simple jet injection technique.

11 Nov 2020

Uracil point mutations found in SARS-CoV-2 variants alter innate immune responses

Tohoku University scientists have found that human editing enzymes are likely behind a type of mutation in the COVID-19 virus that stimulates the release of pro-inflammatory molecules called cytokines by immune cells in the body.

11 Nov 2020

Host genetic "super-variants" may increase COVID-19 death risk

Researchers at Yale University have identified genetic variants among people of white British ancestry that may increase the risk of dying from coronavirus disease 2019 (COVID-19) – the illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

11 Nov 2020

Study identifies genetic risk for fatal blood clots in IBD patients

Blood clots are the biggest cause of death in patients with inflammatory bowel disease (IBD) ─ ulcerative colitis or Crohn's disease. In a retrospective study recently published in the journal Gastroenterology, Cedars-Sinai investigators found that a combination of rare and common genetic variants in some IBD patients significantly increased their risk of developing clot-causing thromboembolic diseases.

11 Nov 2020

IU researcher awarded NCI grant to develop a drug for making radiation therapy more effective

An Indiana University Melvin and Bren Simon Comprehensive Cancer Center researcher has been awarded a five-year, $2.9 million grant from the National Cancer Institute to develop a drug that could make radiation therapy far more effective.

11 Nov 2020

Five important questions about Pfizer’s COVID-19 vaccine

Pfizer's announcement on Monday that its COVID-19 shot appears to keep nine in 10 people from getting the disease sent its stock price rocketing. Many news reports described the vaccine as if it were our deliverance from the pandemic, even though few details were released.

11 Nov 2020

Effectiveness of vitamin C against COVID-19 depends on its natural transporter levels

High doses of vitamin C under study for treating COVID-19 may benefit some populations, but investigators exploring its potential in aging say key factors in effectiveness include levels of the natural transporter needed to get the vitamin inside cells.

11 Nov 2020

Study: Sleep loss hijacks the brain's ability to unlearn fear-related memories

Sleep is crucial for consolidating our memories, and sleep deprivation has long been known to interfere with learning and memory.

11 Nov 2020

Gene signature may help develop new therapies against advanced prostate cancer

Researchers have identified a genetic signature in localized prostate cancer that can predict whether the cancer is likely to spread, or metastasize, early in the course of the disease and whether it will respond to anti-androgen therapy, a common treatment for advanced disease.

11 Nov 2020

Genetic News and Research

Rhesus monkeys and cats potential spillover reservoirs for COVID-19 virus

Researchers discover a mechanism that cells use to degrade microRNAs

Return of mice to home cage evokes significant rise in dopamine release, shows study

Nursing homes still see dangerously long waits for COVID test results

TMDU and Fujitsu complete cancer gene network analysis in less than a day

Men and women may require different brain tumor therapy, study finds

Comparison of 240 mammal genomes helps geneticists to identify disease mutations

Researchers uncover potential genetic target for treating endometriosis

Spike-based DNA vaccine shows excellent protection against SARS-CoV-2 in a hamster model

Uracil point mutations found in SARS-CoV-2 variants alter innate immune responses

Host genetic "super-variants" may increase COVID-19 death risk

Study identifies genetic risk for fatal blood clots in IBD patients

IU researcher awarded NCI grant to develop a drug for making radiation therapy more effective

Five important questions about Pfizer’s COVID-19 vaccine

Effectiveness of vitamin C against COVID-19 depends on its natural transporter levels

Study: Sleep loss hijacks the brain's ability to unlearn fear-related memories

Gene signature may help develop new therapies against advanced prostate cancer

Study: Optogenetic stimulation of circuit improves symptomatology of Huntington's disease

Dietary induction of hepatocyte regeneration may be a viable strategy to enhance gene repair

Two paralogous androgen receptor genes control social dominance

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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