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Immunotherapy in conjunction with drugs could be effective in treating pancreatic cancer

While immune therapy has proven effective in treating certain types of cancer, especially lung cancer and melanoma, tumors of the pancreas remain among the most difficult to treat and, so far, are impervious to immune-based therapies.

4 Jul 2016

Researchers identify non-coding RNA NEAT1 as potential drug target to combat cancer

A team of researchers led by professor Jean-Christophe Marine has identified NEAT1, a non-coding RNA, as a potential therapeutic target in the fight against cancer.

4 Jul 2016

TAILOR study shows treatment with Erbitux plus FOLFOX improves survival in RAS wild-type mCRC patients

Merck, a leading science and technology company, will present data at the ESMO 18th World Congress on Gastrointestinal Cancer from the pivotal Phase III TAILOR study in patients from China, the first prospective trial to evaluate an anti-EGFR antibody in the first-line therapy of patients with RAS wild-type metastatic colorectal cancer (mCRC).

4 Jul 2016

Novel anti-interleukin 1-alpha antibody shows promise in treating advanced colorectal cancer patients

A novel anti-interleukin 1-alpha antibody has shown a significant impact on symptoms, and a high level of safety and tolerability in patients with advanced colorectal cancer, according to phase III data presented at the European Society for Medical Oncology's 18th World Congress of Gastrointestinal Cancer in Barcelona, Spain.

4 Jul 2016

Scientists develop new vaccine to stimulate both innate and specific adaptive response

Though a variety of immunotherapy-based strategies are being used against cancer, they are often hindered by the inability of the immune response to enter the immunosuppressive tumor microenvironment and to effectively mount a response to cancer cells.

1 Jul 2016

Targeted molecular therapy reduces initial development of NAFLD in mice

Researchers report in the journal Cell Reports a targeted molecular therapy that dramatically reduces the initial development of Non Alcoholic Fatty Liver Disease (NAFLD) in laboratory mouse models of the disease.

1 Jul 2016

New technique can help identify aggressive forms of DCIS

When a woman is diagnosed with the earliest stage of breast cancer, how aggressive should her treatment be? Will the non-invasive cancer become invasive? Or is it a slow-growing variety that will likely never be harmful?

1 Jul 2016

Kataegis linked to better prognosis for breast cancer patients

Kataegis is a recently discovered phenomenon in which multiple mutations cluster in a few hotspots in a genome. The anomaly was previously found in some cancers, but it has been unclear what role kataegis plays in tumor development and patient outcomes.

1 Jul 2016

Regorafenib drug improves survival rates in patients with hepatocellular carcinoma

Oral multikinase inhibitor regorafenib achieves significantly improved survival rates compared to placebo in patients with hepatocellular carcinoma, according to data from the phase III RESORCE trial, presented at the ESMO 18th World Congress of Gastrointestinal Cancer in Barcelona, Spain.

30 Jun 2016

Breakthrough research could lead to new drugs to improve heart attack outcomes

A research advance from the Sanford Burnham Prebys Medical Discovery Institute and Stanford University could lead to new drugs that minimize the damage caused by heart attacks.

30 Jun 2016

Scientists gain new insights into how cancer cells may squeeze through narrow blood vessels

The spread of cancer from a tumor's original location to other parts of the body can play a major role in whether the disease turns deadly. Many steps in this process, called metastasis, remain murky.

30 Jun 2016

Researcher identifies how Itch protein inhibits colonic inflammation and carcinogenesis

Venuprasad Poojary, PhD, an associate investigator at Baylor Institute for Immunology Research (BIIR), part of Baylor Scott & White Research Institute, reported this week in the journal Nature Immunology the role of a key protein in the regulatory pathway that is involved in limiting colon inflammation and tumor growth.

30 Jun 2016

Study focuses on critical proteins involved in ovarian cancer biology

In what is believed to be the largest study of its kind, scientists at the Pacific Northwest National Laboratory, Johns Hopkins University and their collaborators from institutions across the nation have examined the collections of proteins in the tumors of 169 ovarian cancer patients to identify critical proteins present in their tumors.

30 Jun 2016

Scientists develop new nonradioactive method to determine telomere length

UT Southwestern Medical Center cell biologists have identified a new method for determining the length of telomeres, the endcaps of chromosomes, which can influence cancer progression and aging.

30 Jun 2016

Researcher receives federal grant to advance study of tumor nanoimmunology

The five-year grant was awarded by the National Cancer Institute of the National Institutes of Health. The funds come on top of four previous grants to support Ljubimova's work. In all, the institute has awarded Ljubimova $16.5 million over the last five years.

29 Jun 2016

Structures on surface of pneumococci determine bacteria’s ability to cause meningitis

Structures on the surface of pneumococci determine the ability of these bacteria to enter the brain and cause severe infections, according to a paper published in The Journal of Clinical Investigation by researchers at Karolinska Institutet.

29 Jun 2016

Compounds extracted from parsley and dill seeds may help fight cancer

A team of Russian scientists from Moscow Institute of Physics and Technology, the N. D. Zelinsky Institute of Organic Chemistry, the Institute of Developmental Biology, and the Institute of Cell Biophysics proposed an efficient approach to a novel agents with anticancer activity.

29 Jun 2016

Tumor News and Research

Immunotherapy in conjunction with drugs could be effective in treating pancreatic cancer

Researchers identify non-coding RNA NEAT1 as potential drug target to combat cancer

TAILOR study shows treatment with Erbitux plus FOLFOX improves survival in RAS wild-type mCRC patients

Novel anti-interleukin 1-alpha antibody shows promise in treating advanced colorectal cancer patients

Scientists develop new vaccine to stimulate both innate and specific adaptive response

Targeted molecular therapy reduces initial development of NAFLD in mice

New technique can help identify aggressive forms of DCIS

Kataegis linked to better prognosis for breast cancer patients

Regorafenib drug improves survival rates in patients with hepatocellular carcinoma

Breakthrough research could lead to new drugs to improve heart attack outcomes

Scientists gain new insights into how cancer cells may squeeze through narrow blood vessels

Researcher identifies how Itch protein inhibits colonic inflammation and carcinogenesis

Study focuses on critical proteins involved in ovarian cancer biology

Scientists develop new nonradioactive method to determine telomere length

Researcher receives federal grant to advance study of tumor nanoimmunology

Structures on surface of pneumococci determine bacteria’s ability to cause meningitis

Compounds extracted from parsley and dill seeds may help fight cancer

Bioengineers develop 2-in-1 nanomedicine for treating cancer

Scientists develop computational method to map cancer progression

Deficiency in NMD could cause inflammatory myofibroblastic tumors

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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