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Time machine suggests a drug testing approach for pancreatic cancer

Many patients with pancreatic cancer have only about a 10% chance of survival within five years of their diagnosis because they tend to become resistant to chemotherapy, past studies have indicated.

30 Oct 2020

Study sheds new light on the biological base of psychotic symptoms

Anti-NMDAR encephalitis is an autoimmune brain illness that is often mistaken by a psychiatric disorder since it causes psychoses and other behaviour alterations. Despite having these similarities, the illness does not respond to common antipsychotic treatments.

30 Oct 2020

Moscow scientists discover and explain the activity mechanism of new anti-cancer molecule

A group of Moscow scientists has discovered and explained the activity mechanism of a new anti-cancer molecule -- diphenylisoxazole.

29 Oct 2020

More intensive, less frequent drug regimen could cure Chagas disease

Researchers in the University of Georgia's Center for Tropical and Emerging Global Diseases have found that a more intensive, less frequent drug regimen with currently available therapeutics could cure the infection that causes Chagas disease, a potentially life-threatening illness affecting up to 300,000 people in the United States.

29 Oct 2020

Study sheds light on the biological base of symptoms in autoimmune psychosis

29 Oct 2020

Study reveals how gene control mechanisms define the identity of developing brainstem neurons

A recent study at the University of Helsinki reveals how gene control mechanisms define the identity of developing neurons in the brainstem.

29 Oct 2020

Intercellular communication pathway drives motivation to seek cocaine

In the October 28, 2020 issue of the Journal of Neuroscience, researchers from the Medical University of South Carolina and the National Institutes of Health describe how reminders of drug use can change specific brain cells responsible for motivation, increasing the desire to seek drugs.

29 Oct 2020

App-based companies pushing Prop. 22 say drivers will get health benefits. Will they?

App-based driving services such as Uber, Lyft, DoorDash and Instacart are bankrolling California's Proposition 22, which would keep their drivers classified as independent contractors, not employees.

29 Oct 2020

New study may help combat loss of muscle mass associated with aging

Researchers at the University of São Paulo (USP) in Brazil have discovered that the muscle regeneration promoted by aerobic exercise is mediated by changes in oxygen consumption by satellite cells, also known as skeletal muscle stem cells.

29 Oct 2020

Exposure to artemisinin drug could increase sexual conversion rate of malaria parasite

Exposure to suboptimal doses of the antiparasitic drug artemisinin could increase the sexual conversion rate of the malaria parasite Plasmodium falciparum, thereby increasing the probability of transmission, according to a study led by the Barcelona Institute for Global Health (ISGlobal), an institution supported by "la Caixa" Foundation.

29 Oct 2020

Researchers develop controllable system for mimicking biochemical reaction cascades in cells

Researchers at the University of Basel have developed a precisely controllable system for mimicking biochemical reaction cascades in cells.

29 Oct 2020

Researchers observe a rapid drop in average body temperature in tropical human population

In the nearly two centuries since German physician Carl Wunderlich established 98.6°F as the standard "normal" body temperature, it has been used by parents and doctors alike as the measure by which fevers -- and often the severity of illness -- have been assessed.

29 Oct 2020

Antiseizure drug use during pregnancy linked with double the risk of having children with autism

Women with epilepsy who take the antiseizure drug valproic acid while pregnant are at more than double the risk of having children with autism spectrum disorder and nearly double the risk of having children with attention deficit hyperactivity disorder (ADHD), according to a study in the October 28, 2020, online issue of Neurology, the medical journal of the American Academy of Neurology.

28 Oct 2020

Genome-wide CRISPR screens reveal resistance and sensitization mechanisms of drugs used in COVID-19

By leveraging nucleotide triphosphate analog-induced cell death, Chinese researchers unveiled genes that affect the import, export, and metabolism of pervasively used antiviral drugs in the treatment of coronavirus disease (COVID-19). This exciting study is currently available on the bioRxiv* preprint server.

28 Oct 2020

Glucose-lowering drug can protect the kidneys in patients with type 1 diabetes, study shows

A glucose-lowering drug commonly used in patients with type 2 diabetes, can protect the kidneys in patients with type 1 diabetes. According to results shown in a new study published in the Lancet.

28 Oct 2020

Deep learning models help hunt for COVID-19 drugs

Michigan State University Foundation Professor Guowei Wei wasn't preparing machine learning techniques for a global health crisis. Still, when one broke out, he and his team were ready to help.

28 Oct 2020

Sleep could be targeted to improve post-stroke recovery, study shows

Until today neurorehabilitation is the only approach that promotes recovery after stroke. Researchers at the Neurology Department of the University of Bern and Inselspital have provided first evidence that sleep could be targeted to improve post-stroke recovery.

28 Oct 2020

CN Bio announces launch of drug metabolism and safety toxicity testing services

CN Bio, a leading 3D cell culture company, that has developed single and multi-organ microphysiological systems to improve the accuracy and efficiency of drug discovery, today announced the commercial launch of its Drug Metabolism and Safety Toxicity Testing Services.

28 Oct 2020

Scientists compare ACE2 interaction with SARS-CoV-2 across species

Like other pathogenic coronaviruses, SARS-CoV-2 crossed the species barrier to cause human disease. This fact motivated the current study, published on the preprint server bioRxiv* in October 2020, which explores the way coronaviruses engage their host cell receptors in a range of animals.

28 Oct 2020

Structure and mechanisms of ribosomal frameshifting during SARS-CoV-2 translation

The structure of a 3’ stimulatory pseudoknot in the viral genome or by itself has been proposed recently. Researchers report the structure and mechanisms of mammalian ribosomes during translation of the -1 frameshifting of the SARS-CoV-2 viral genome in a new study published on the preprint server bioRxiv.

28 Oct 2020

Drugs News and Research

Time machine suggests a drug testing approach for pancreatic cancer

Study sheds new light on the biological base of psychotic symptoms

Moscow scientists discover and explain the activity mechanism of new anti-cancer molecule

More intensive, less frequent drug regimen could cure Chagas disease

Study sheds light on the biological base of symptoms in autoimmune psychosis

Study reveals how gene control mechanisms define the identity of developing brainstem neurons

Intercellular communication pathway drives motivation to seek cocaine

App-based companies pushing Prop. 22 say drivers will get health benefits. Will they?

New study may help combat loss of muscle mass associated with aging

Exposure to artemisinin drug could increase sexual conversion rate of malaria parasite

Researchers develop controllable system for mimicking biochemical reaction cascades in cells

Researchers observe a rapid drop in average body temperature in tropical human population

Antiseizure drug use during pregnancy linked with double the risk of having children with autism

Genome-wide CRISPR screens reveal resistance and sensitization mechanisms of drugs used in COVID-19

Glucose-lowering drug can protect the kidneys in patients with type 1 diabetes, study shows

Deep learning models help hunt for COVID-19 drugs

Sleep could be targeted to improve post-stroke recovery, study shows

CN Bio announces launch of drug metabolism and safety toxicity testing services

Scientists compare ACE2 interaction with SARS-CoV-2 across species

Structure and mechanisms of ribosomal frameshifting during SARS-CoV-2 translation

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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