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New blood biomarkers could lead to better evaluation of treatment for patients with PAH

New blood biomarkers reflecting vasoreactivity in lung blood vessels of patients with heart- and lung disease, can lead to simplified diagnostics and better evaluation of treatment for patients with the condition pulmonary arterial hypertension (PAH).

18 Jan 2016

UM SOM selected to work with BARDA to develop radiologic and nuclear countermeasures

University of Maryland School of Medicine Department of Radiation Oncology Chair and Professor William F. Regine, MD, FACR, FACRO, and UM SOM Dean E. Albert Reece, MD, PhD, MBA, announced today that researchers at the UM SOM have been selected as key contractors by the Biomedical Advanced Research and Development Authority, for its Radiation Nuclear Animal Model Development program.

18 Jan 2016

Frozen fecal transplantation effective at providing relief to C. diff patients

Frozen fecal transplantation is effective at providing relief to Clostridium difficile (C. diff) patients, according to a new study co-authored by University of Guelph researchers.

18 Jan 2016

Scientists find new way to re-engineer body’s immune system to target cancer

Scientists have demonstrated a new way of re-engineering the body’s immune system to target cancer, paving the way for a new generation of drugs, unprecedented in safety and effectiveness.

18 Jan 2016

New study finds efficacy of novel intravenous blood thinner in women

Percutaneous coronary intervention (PCI) is a staple of modern day medicine in which cardiologists place a stent in a blood vessel around the heart in order to restore blood flow in people with heart disease. Blood thinners allow for the procedure to be completed with a reduced risk of certain complications such as clots.

18 Jan 2016

Large-scale clinical trial to evaluate dengue vaccine launched in Brazil

A large-scale clinical trial to evaluate whether a candidate vaccine can prevent the mosquito-borne illness dengue fever has been launched in Brazil. The vaccine, TV003, was developed by scientists in the laboratory of Stephen Whitehead, Ph.D., at NIH's National Institute of Allergy and Infectious Diseases (NIAID).

17 Jan 2016

Novartis announces FDA approval of Cosentyx for treatment of adult patients with AS and PsA

Novartis announced today that the US Food and Drug Administration has approved Cosentyx (secukinumab) for two new indications - the treatment of adult patients with active ankylosing spondylitis (AS) and active psoriatic arthritis (PsA).

17 Jan 2016

Long-term use of opioids increases risk of new-onset depression

Opioids may cause short-term improvement in mood, but long-term use imposes risk of new-onset depression, a Saint Louis University study shows.

13 Jan 2016

First patient enrolled in ThromboGenics' Phase II CIRCLE study of ocriplasmin in NPDR patients

ThromboGenics NV, an integrated biopharmaceutical company focused on developing and commercializing innovative treatments for diabetic eye disease, today announces that the first patient has been enrolled in its Phase II CIRCLE study evaluating the efficacy and safety of multiple doses of ocriplasmin in inducing total posterior vitreous detachment (PVD) in patients with non-proliferative diabetic retinopathy (NPDR).

13 Jan 2016

AbbVie begins six global Phase 3 clinical studies to evaluate efficacy of investigational HCV regimen

AbbVie, a global biopharmaceutical company, today announced the initiation of six global Phase 3 clinical studies evaluating the safety and efficacy of its all-oral, once-daily, ribavirin-free investigational hepatitis C virus (HCV) regimen, ABT-493, an NS3/4A protease inhibitor, and ABT-530, an NS5A inhibitor, in patients with genotypes 1-6 (GT1-6) chronic HCV infection.

12 Jan 2016

Vagus nerve stimulation effective in inhibiting cortical spreading depression

According to a study led by scientists at Massachusetts General Hospital, Harvard Medical School published in the journal Pain, vagus nerve stimulation (VNS) was found to suppress cortical spreading depression (CSD).

12 Jan 2016

Sage Analytics establishes distribution network in South America

Sage Analytics, the developers of portable, laboratory-quality cannabis potency measurement systems, announced it established a distribution network in South America, anchored by Senses Biotech in Uruguay.

11 Jan 2016

Global supply of oral cholera vaccines expected to double with new producer

The global supply of oral cholera vaccines is set to double after WHO approved a third producer, helping to address global shortages and expand access in more countries.

11 Jan 2016

Virginia Tech scientists find potential way to influence memory formation in the immune system

Scientists at the Virginia Tech Carilion Research Institute have found a potential way to influence long-term memory formation in the immune system. The researchers published their results today in Nature Communications.

11 Jan 2016

NUS-led study discovers potential therapeutic approach against colorectal cancer

A study led by researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) has demonstrated the efficiency of a small molecule drug, PRIMA-1met, in inhibiting the growth of colorectal cancer cells. Colorectal cancer is the cancer of the large intestine (colon and rectum) and is the most common cancer in Singapore.

11 Jan 2016

Patient recommendations for rheumatoid arthritis treatment: an interview with Dr Nowell

The study, “When patients write the guidelines: Patient panel recommendations for the treatment of RA,” published in Arthritis Research & Care, demonstrated the feasibility of developing CPG recommendations based on a voting panel composed entirely of patients.

8 Jan 2016

Early promise for cannabis extract treatment in epilepsy

A preliminary, open-label study suggests that cannabidiol may be a useful adjunctive treatment in adults and children with intractable epilepsy.

7 Jan 2016

Largest real world study to date demonstrate effectiveness of biosimilar infliximab in patients with inflammatory bowel diseases who have been switched from reference infliximab

Data from the PRospective Observational cohort Study on patients with Inflammatory bowel disease receiving Therapy with BIOsimilars (PROSIT-BIO) in patients with ulcerative colitis (UC) and Crohn’s disease (CD) has been presented at the Italian Group for the Study of IBD (IG-IBD), VII National Congress, Palermo, Italy.

7 Jan 2016

Avalon Healthcare Solutions receives additional investment from Francisco Partners

Avalon Healthcare Solutions today announced a second round of investment from Francisco Partners. The incremental capital will be used to enhance Avalon's comprehensive laboratory management technology and clinical capabilities, as well as to strengthen growth opportunities.

7 Jan 2016

New injectable agent can potentially increase surgeon's ability to remove cancerous tumor during surgery

Doctors at the Duke University School of Medicine have tested a new injectable agent that causes cancer cells in a tumor to fluoresce, potentially increasing a surgeon's ability to locate and remove all of a cancerous tumor on the first attempt. The imaging technology was developed through collaboration with scientists at Duke, the Massachusetts Institute of Technology and Lumicell Inc.

7 Jan 2016

Efficacy News and Research

New blood biomarkers could lead to better evaluation of treatment for patients with PAH

UM SOM selected to work with BARDA to develop radiologic and nuclear countermeasures

Frozen fecal transplantation effective at providing relief to C. diff patients

Scientists find new way to re-engineer body’s immune system to target cancer

New study finds efficacy of novel intravenous blood thinner in women

Large-scale clinical trial to evaluate dengue vaccine launched in Brazil

Novartis announces FDA approval of Cosentyx for treatment of adult patients with AS and PsA

Long-term use of opioids increases risk of new-onset depression

First patient enrolled in ThromboGenics' Phase II CIRCLE study of ocriplasmin in NPDR patients

AbbVie begins six global Phase 3 clinical studies to evaluate efficacy of investigational HCV regimen

Vagus nerve stimulation effective in inhibiting cortical spreading depression

Sage Analytics establishes distribution network in South America

Global supply of oral cholera vaccines expected to double with new producer

Virginia Tech scientists find potential way to influence memory formation in the immune system

NUS-led study discovers potential therapeutic approach against colorectal cancer

Patient recommendations for rheumatoid arthritis treatment: an interview with Dr Nowell

Early promise for cannabis extract treatment in epilepsy

Largest real world study to date demonstrate effectiveness of biosimilar infliximab in patients with inflammatory bowel diseases who have been switched from reference infliximab

Avalon Healthcare Solutions receives additional investment from Francisco Partners

New injectable agent can potentially increase surgeon's ability to remove cancerous tumor during surgery

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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