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RowanSOM researcher awarded NINDS grant to develop stem cell-based therapy for Canavan disease

Paola Leone, PhD, the director of the Cell and Gene Therapy Center and a professor of Cell Biology at the Rowan University School of Osteopathic Medicine, has been awarded a three-year, $477,000 grant from the National Institute of Neurological Disorders and Stroke to develop a stem cell-based therapy for Canavan disease, a rare but devastating neurological disorder in children that typically takes a child's life by age 10.

26 Feb 2015

Sleeping more than eight hours a night could increase risk of stroke

People who sleep more than eight hours a night may have an increased risk of stroke, according to a new study published in the February 25, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

26 Feb 2015

Preliminary NIBIB-funded study may improve prediction of mild traumatic brain injury

A preliminary study conducted by researchers funded by the National Institute of Biomedical Imaging and Bioengineering may improve our prediction of mild traumatic brain injury (mTBI). Every year more than 40 million people worldwide suffer from mTBI. 3.8 million concussions occur in the US each year during sports and recreation alone.

26 Feb 2015

Study points respiratory viruses as the most common cause of childhood pneumonia

Respiratory viruses, not bacterial infections, are the most commonly detected causes of community-acquired pneumonia in children, according to new research released Feb. 26 in the New England Journal of Medicine.

26 Feb 2015

New four-way collaboration aims to improve clinical decision-making in the treatment of colon cancer

EKF Diagnostics subsidiary, Selah Genomics, has announced a major, four-way collaboration with Greenville Health System, DecisionQ Corporation, and BD.

From EKF Diagnostics 26 Feb 2015

Hospira launches first biosimilar monoclonal antibody (mAb) InflectraTM (infliximab) in the UK

Inflectra is licensed for the treatment of inflammatory conditions including rheumatoid arthritis (RA), psoriatic arthritis, ankylosing spondylitis, adult and paediatric Crohn’s disease, adult and paediatric ulcerative colitis and plaque psoriasis.

26 Feb 2015

UK scientists find new approach to treat Parkinson's disease

UK scientists have developed a peptide that sticks to the protein that causes Parkinson's disease, stopping it from killing brain cells. The research highlights a potential new route for slowing the progress of this incurable disease.

26 Feb 2015

Researchers introduce the idea of using sewage to study human microbiome

A new study demonstrates that sewage is an effective means to sample the fecal bacteria from millions of people. Researchers say the information gleaned from the work provides a unique opportunity to monitor, through gut microbes, the public health of a large population without compromising the privacy of individuals.

26 Feb 2015

Frailty assessment test can accurately predict complications after major operation

Frailty has been used to predict how well a patient may recover from a major operation. Because frailty assessments are not routinely utilized in busy surgical practices, surgeons at Emory University School of Medicine in Atlanta have discovered that a short, approximately one-minute assessment can accurately determine how likely a patient is to have complications after an operation.

26 Feb 2015

TSRI study finds no evidence of increased aggressive behavior toward strangers in autism model

While aggression toward caregivers and peers is a challenge faced by many individuals and families dealing with autism, there has been much speculation in the media over the possibility of generally heightened aggression in those diagnosed with autism spectrum disorder. A new study by scientists from the Florida campus of The Scripps Research Institute found no evidence of increased aggressive behavior toward strangers in an animal model of the condition.

26 Feb 2015

Novel technology could improve diagnosis of peripheral arterial disease

Approximately 8 to 12 million people in the United States alone are suffering from peripheral arterial disease (PAD), a common vascular problem that is caused by narrowing of the arteries as a result of plaque buildup. The plaque accumulation leads to an insufficient blood flow to the body's extremities and increases a person's risk for heart attack and stroke by up to six times. PAD is also one of the most serious complications of diabetes.

26 Feb 2015

Intrinsically disordered proteins have ability to alter their configuration

Like the shape-shifting robots of "Transformers" fame, a unique class of proteins in the human body also has the ability to alter their configuration. These so-named intrinsically disordered proteins (IDPs) lack a fixed or ordered three-dimensional structure, which can be influenced by exposure to various chemicals and cellular modifications.

26 Feb 2015

Study: Plant compounds can help prevent liver damage during menopause

Women going through menopause often struggle with weight gain that results when their estrogen levels drop, and many turn to weight-loss supplements to help them shed those extra pounds. But those supplements may cause an accumulation of fat in the liver and a potentially life-threatening condition called non-alcoholic fatty liver disease.

26 Feb 2015

Scientists identify novel gene that affects brain function

U.S. and Australian scientists have found the mechanism a novel gene uses to affect brain function and elicit behavior related to neuropsychiatric disease.

26 Feb 2015

Scientists discover DNA vaccine that alleviates chronic inflammation in the body

An international team of scientists including CureLab Oncology, Inc. (Boston), University of Camerino (Italy), and Boston University have serendipitously discovered a DNA vaccine, which systemically alleviates chronic inflammation in the body. Since osteoporosis is an inflammatory disease, preventive and therapeutic effects of the new vaccine were demonstrated on mouse models with osteoporosis.

26 Feb 2015

Researchers warn doctors, parents not to give melatonin drug to control sleep problems in children

Sleep researchers at the University of Adelaide are warning doctors and parents not to provide the drug melatonin to children to help control their sleep problems.

26 Feb 2015

New medical device could revolutionise kidney disease care in the UK

A new medical device which combines nanotechnology with a pregnancy tester could help diagnose and treat the 1 million people in the UK who don’t know they have kidney disease, a new report by the Institution of Mechanical Engineers reveals today.

26 Feb 2015

Prexton closes €8.7 million in Series A financing to develop treatments for Parkinson’s disease

Prexton Therapeutics, a biopharmaceutical company developing novel therapeutic compounds for the treatment of CNS conditions including Parkinson’s disease, today announces the closing of a Series A financing of €8.7 million ($10 million) co-led by Sunstone Capital and Ysios Capital.

26 Feb 2015

Researchers reveal how malaria parasite deploys genetic trickery to escape immune system attack

Up to one million people -- mainly pregnant woman and young children -- are killed each year by the Plasmodium falciparum parasite, which causes the most devastating form of human malaria.

26 Feb 2015

Johns Hopkins-led study reveals impact of hospital setting on patient satisfaction

Contrary to previous reports, a study led by Johns Hopkins researchers found that patients’ satisfaction scores only modestly improved based on the newly remodeled design of a hospital.

26 Feb 2015

Research News and Research

RowanSOM researcher awarded NINDS grant to develop stem cell-based therapy for Canavan disease

Sleeping more than eight hours a night could increase risk of stroke

Preliminary NIBIB-funded study may improve prediction of mild traumatic brain injury

Study points respiratory viruses as the most common cause of childhood pneumonia

New four-way collaboration aims to improve clinical decision-making in the treatment of colon cancer

Hospira launches first biosimilar monoclonal antibody (mAb) InflectraTM (infliximab) in the UK

UK scientists find new approach to treat Parkinson's disease

Researchers introduce the idea of using sewage to study human microbiome

Frailty assessment test can accurately predict complications after major operation

TSRI study finds no evidence of increased aggressive behavior toward strangers in autism model

Novel technology could improve diagnosis of peripheral arterial disease

Intrinsically disordered proteins have ability to alter their configuration

Study: Plant compounds can help prevent liver damage during menopause

Scientists identify novel gene that affects brain function

Scientists discover DNA vaccine that alleviates chronic inflammation in the body

Researchers warn doctors, parents not to give melatonin drug to control sleep problems in children

New medical device could revolutionise kidney disease care in the UK

Prexton closes €8.7 million in Series A financing to develop treatments for Parkinson’s disease

Researchers reveal how malaria parasite deploys genetic trickery to escape immune system attack

Johns Hopkins-led study reveals impact of hospital setting on patient satisfaction

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