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Epigenome-wide association study helps discover genes linked to allergies and asthma

Researchers from Canada, the UK, Sweden and the US have discovered more than 30 genes that strongly affect an antibody involved in allergies and asthma. Some of the genes could provide targets for drugs to treat those conditions, according to the international team's study, published online in Nature on Feb. 18.

20 Feb 2015

Researchers review ten years of scientific studies on mitochondrial toxicity in pregnant women

Researchers from the Hospital Clinic of Barcelona (Spain) have reviewed ten years' worth of scientific studies on mitochondrial toxicity in pregnant women. Exposure to toxic agents such as viruses, certain drugs, pesticides, alcohol and tobacco cause mitochondrial diseases about which very little is known, and which are transmitted from the mother to the foetus.

20 Feb 2015

Industrial Biotechnology presents insights on cellulose nanocrystal toxicity

Novel nanomaterials derived from cellulose have many promising industrial applications, are biobased and biodegradable, and can be produced at relatively low cost. Their potential toxicity--whether ingested, inhaled, on contact with the skin, or on exposure to cells within the body--is a topic of intense discussion, and the latest evidence and insights on cellulose nanocrystal toxicity are presented in a Review article in Industrial Biotechnology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

20 Feb 2015

Research findings lay groundwork for improving treatment assessment for men with prostate cancer

UCLA researchers have found that radiation therapy is the most common treatment for men with prostate cancer regardless of the aggressiveness of the tumor, risk to the patient and overall patient prognosis. These findings lay the groundwork for improved treatment assessment by physicians and to better inform men fighting the disease.

20 Feb 2015

New planning tool helps identify patients' risks of chronic pain after surgery

There are many variables that contribute to a patient's risk of chronic pain after surgery; physicians are still exploring ways to identify those variables prior to surgery.

20 Feb 2015

Philadelphia College of Osteopathic Medicine professor explores causes, treatments of anorexia

Eating disorders are serious, debilitating conditions associated with significant morbidity and mortality, and distress. Anorexia nervosa, in particular, is associated with the highest mortality and suicide rates; compared to healthy peers, women with anorexia are up to 12 times more likely to die of any cause, and approximately 57 times more likely to die from suicide, over the same period of time.

20 Feb 2015

New partnership aims to create stem cell resource to study psychiatric disorders

The New York Stem Cell Foundation and the Stanley Center at the Broad Institute of MIT and Harvard are partnering to create a foundational stem cell resource to study psychiatric disorders through the production of induced pluripotent stem (iPS) cell lines from individuals with schizophrenia and other psychiatric disorders.

20 Feb 2015

Sensor technology has potential to improve teaching of proper CBE techniques

Sensor technology has the potential to significantly improve the teaching of proper technique for clinical breast exams (CBE), according to a new study by researchers at the University of Wisconsin School of Medicine and Public Health.

20 Feb 2015

Study compares two different methods of blood transfusion in trauma care

The University of Maryland School of Medicine is part of a new nationwide, multi-site study that may help save hundreds of lives among trauma patients with major bleeding. The study, which was published earlier this month in JAMA, compared two different methods of blood transfusion, and found that one approach gave patients a significantly better chance of survival within the first 24 hours.

20 Feb 2015

Majority of women support idea of more frequent breast screening for individuals at higher risk of cancer

Most women (85 per cent) would back the idea of more frequent breast screening if they are at higher genetic risk of developing breast cancer, according to research published today by The Breast.

20 Feb 2015

Study: Growth hormone can improve social impairment in patients with Phelan-McDermid syndrome

A growth hormone can significantly improve the social impairment associated with autism spectrum disorder (ASD) in patients with a related genetic syndrome, according to a pilot study conducted at the Icahn School of Medicine at Mount Sinai and published yesterday on Pub Med, a public database of biomedical topics maintained by the National Institutes of Health (study originally published in the December 12 issue of the journal Molecular Autism).

20 Feb 2015

New study finds that statins may not reduce risk for Parkinson's disease

The use of statins may not be associated with lowering risk for Parkinson's disease, according to a new study led by researchers at Penn State College of Medicine and National Institute of Environmental Health Sciences. The findings cast doubts on reports suggesting that the cholesterol-lowering medications may protect against this neurodegenerative brain disorder.

20 Feb 2015

Researchers demonstrate clinical efficacy of gallopamil in severe asthma patients

A team of Inserm researchers from the Cardio-Thoracic Research Centre of Bordeaux (Inserm/University of Bordeaux and Bordeaux University Hospital) has demonstrated the clinical efficacy of gallopamil in 31 patients with severe asthma. This chronic disease is characterised by remodelling of the bronchi, which exacerbates the obstruction of the airways already seen in "classic" asthma.

20 Feb 2015

IUPUI's Jason Meyer awarded $1.8 million NIH grant to explore how glaucoma develops in stem cells

Jason Meyer, Ph.D., assistant professor of biology in the School of Science at Indiana University-Purdue University Indianapolis, has received a National Institutes of Health grant to study how glaucoma develops in stem cells created from skin cells genetically predisposed to the disease.

20 Feb 2015

Unhealthy foods outpace beneficial dietary changes in middle-income nations

In a first-of-its-kind analysis of worldwide dietary patterns, a team including researchers from the Friedman School of Nutrition Science and Policy at Tufts University and the Medical Research Council Epidemiology Unit, University of Cambridge found overall diet quality worsened across the world even as consumption of healthier foods increased in many countries.

20 Feb 2015

New research finds that synthetic flame retardants can cause metabolic and liver problems

Chemicals used as synthetic flame retardants that are found in common household items such as couches, carpet padding, and electronics have been found to cause metabolic and liver problems that can lead to insulin resistance, which is a major cause of obesity, according to new research from the University of New Hampshire.

20 Feb 2015

MIT chemical engineers develop new type of self-healing hydrogel

Scientists are interested in using gels to deliver drugs because they can be molded into specific shapes and designed to release their payload over a specified time period. However, current versions aren't always practical because must be implanted surgically.

20 Feb 2015

Georgia State signs license agreement with Cisen to develop compounds for treating cancer

Georgia State University has signed a license agreement with Cisen Pharmaceutical Co. Ltd., a comprehensive pharmaceutical enterprise in China, to develop cancer-fighting compounds designed by Georgia State researcher Dr. Binghe Wang, in collaboration with Professor Muxiang Zhou of Emory University, a cancer biologist.

20 Feb 2015

Clinical study comparing effectiveness of three standard treatments for DME published in NEJM

Regeneron Pharmaceuticals, Inc. today announced that results from the National Institutes of Health-sponsored, Diabetic Retinopathy Clinical Research Network comparative effectiveness study in patients with Diabetic Macular Edema (Protocol T) were published in the New England Journal of Medicine and a corresponding slide set was posted online at DRCR.net.

20 Feb 2015

Scientists identify promising new therapeutic target for prostate cancer

Keck Medicine of the University of Southern California scientists have found a promising new therapeutic target for prostate cancer. The findings offer evidence that a newly discovered member of a family of cell surface proteins called G-protein coupled receptors (GPCRs) promotes prostate cancer cell growth. The protein, GPR158, was found while the researchers were looking for new drug targets for glaucoma.

20 Feb 2015

Research News and Research

Epigenome-wide association study helps discover genes linked to allergies and asthma

Researchers review ten years of scientific studies on mitochondrial toxicity in pregnant women

Industrial Biotechnology presents insights on cellulose nanocrystal toxicity

Research findings lay groundwork for improving treatment assessment for men with prostate cancer

New planning tool helps identify patients' risks of chronic pain after surgery

Philadelphia College of Osteopathic Medicine professor explores causes, treatments of anorexia

New partnership aims to create stem cell resource to study psychiatric disorders

Sensor technology has potential to improve teaching of proper CBE techniques

Study compares two different methods of blood transfusion in trauma care

Majority of women support idea of more frequent breast screening for individuals at higher risk of cancer

Study: Growth hormone can improve social impairment in patients with Phelan-McDermid syndrome

New study finds that statins may not reduce risk for Parkinson's disease

Researchers demonstrate clinical efficacy of gallopamil in severe asthma patients

IUPUI's Jason Meyer awarded $1.8 million NIH grant to explore how glaucoma develops in stem cells

Unhealthy foods outpace beneficial dietary changes in middle-income nations

New research finds that synthetic flame retardants can cause metabolic and liver problems

MIT chemical engineers develop new type of self-healing hydrogel

Georgia State signs license agreement with Cisen to develop compounds for treating cancer

Clinical study comparing effectiveness of three standard treatments for DME published in NEJM

Scientists identify promising new therapeutic target for prostate cancer

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