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Medication holds promise for protecting fertility and the body's defense system during chemotherapy

While targeted cancer treatments have reduced side effects and improved efficacy, chemotherapy remains the backbone of combination therapies for many forms of cancer. Unfortunately, cancer patients may suffer from several side effects from chemotherapy, including infertility and a weakened defense system that makes them susceptible to life-threatening infections.

15 Dec 2015

Social and emotional skills intervention can help young Syrian refugees heal psychological wounds

A social and emotional skills intervention developed to help children recover from the trauma of natural disasters is being adapted to help young Syrian refugees heal their psychological wounds.

15 Dec 2015

ESSA reports net loss of $11.5 million for year ended September 30, 2015

ESSA Pharma Inc. today reported financial results for the year ended September 30, 2015. Amounts, unless specified otherwise, are expressed in Canadian dollars and in accordance with International Financial Reporting Standards ("IFRS").

15 Dec 2015

$Ibrutinib ‘new standard’ for relapsed, refractory mantle cell lymphoma$

Ibrutinib ‘new standard’ for relapsed, refractory mantle cell lymphoma

Phase III trial findings suggest that patients with relapsed or refractory mantle cell lymphoma derive significantly greater benefits from ibrutinib than from temsirolimus therapy.

14 Dec 2015

BTG receives 510k clearance for LC Bead LUMI

BTG plc, a global specialist healthcare company, today announced it has received 510k clearance from the US Food and Drug Administration for LC Bead LUMI, the first commercially available radiopaque embolic bead for the embolization of hypervascular tumors and arteriovenous malformations (AVMs).

14 Dec 2015

Aural feedback can help people to clean their teeth more gently

Researchers in Japan have discovered that how effectively we clean our teeth and how satisfied we are with the brushing job we do depends a lot on the sound of the bristles scrubbing against the enamel. In trials with volunteer teeth cleaners, the team has used a tiny microphone in a modified toothbrush to 'sample' the sound being made in the mouth during brushing and to modulate it and then feed that sound back to the volunteer via headphones to see what effect it would have on cleaning efficacy and satisfaction.

13 Dec 2015

Combination treatment provides effective one-two punch against prostate cancer

Results from a long-term clinical trial conducted by cancer researchers at Houston Methodist Hospital show that combining radiation treatment with "suicide gene therapy," a technique in which prostate cancer cells are genetically modified so they signal a patient's immune system to attack them, provides a safe and effective one-two punch against the disease.

12 Dec 2015

FDA approves Vistogard (uridine triacetate) for emergency treatment of chemotherapy overdose

The U.S. Food and Drug Administration today approved Vistogard (uridine triacetate) for the emergency treatment of adults and children who receive an overdose of the cancer treatment fluorouracil or capecitabine, or who develop certain severe or life-threatening toxicities within four days of receiving these cancer treatments.

12 Dec 2015

Alecensa (alectinib) approved for treatment of people with advanced ALK-positive NSCLC

The U.S. Food and Drug Administration today approved Alecensa (alectinib) to treat people with advanced (metastatic) ALK-positive non-small cell lung cancer (NSCLC) whose disease has worsened after, or who could not tolerate treatment with, another therapy called Xalkori (crizotinib).

11 Dec 2015

Early promise for pulmonary artery denervation in PAH patients

Pulmonary artery denervation is feasible and may reduce pulmonary arterial pressure in patients with pulmonary arterial hypertension, phase II findings suggest.

11 Dec 2015

$Role for carfilzomib in relapsed, refractory multiple myeloma treatment$

Role for carfilzomib in relapsed, refractory multiple myeloma treatment

Carfilzomib significantly improves outcomes in previously treated patients with relapsed or refractory multiple myeloma, shows a head-to-head comparison with bortezomib.

11 Dec 2015

Capecitabine increases disease-free survival for HER2-negative breast cancer patients

Treatment with the chemotherapy agent capecitabine increased disease-free survival for women with HER2-negative breast cancer that was not eliminated by presurgery chemotherapy, according to results from the phase III CREATE-X clinical trial presented at the 2015 San Antonio Breast Cancer Symposium, held Dec. 8-12.

11 Dec 2015

Study reveals why anti-hormone therapy tamoxifen works better in some women than others

The anti-hormone therapy tamoxifen can reduce breast cancer recurrence by about half in women with hormone-sensitive breast cancer. But it works better in some women than others. Researchers are not sure why.

11 Dec 2015

Videregen-led TETRA consortium awarded EUR 6.8 million for pivotal Phase II trial of replacement trachea

The pan-European TETRA consortium, led by Videregen Limited, has been awarded EUR 6.8 million under the Horizon 2020 programme for a pivotal Phase II clinical trial of the company's tissue engineered replacement trachea.

10 Dec 2015

Caregiver-implemented singing beneficial in early stages of dementia

Researchers led by Dr. Teppo Särkämö at University of Helsinki, Finland have revealed that caregiver-implemented musical leisure activities, particularly singing, are cognitively and emotionally beneficial especially in the early stages of dementia. The findings could help improve dementia care and better target the use of music in different stages of dementia.

10 Dec 2015

New class of diabetes drugs differs in efficacy and safety profiles, shows new research

Once-weekly glucagon-like peptide-1 receptor agonists (GLP-1RAs) differ in their efficacy and safety profiles, according to new research by the University of Leicester.

10 Dec 2015

Boehringer Ingelheim begins SENSCIS study to investigate safety, efficacy of nintedanib in patients with SSc-ILD

Boehringer Ingelheim announced today that the first person has been enrolled in the SENSCIS (Safety and Efficacy ofNintedanib in Systemic SClerosIS) study.

10 Dec 2015

Tetra begins human Phase 1 safety trials of BPN14770

Tetra Discovery Partners today announced that the company has initiated human Phase 1 safety trials of its lead compound BPN14770, which Tetra is developing as a potential treatment to both improve memory and slow the progression of Alzheimer's disease.

9 Dec 2015

FDA clears for marketing first cooling cap to reduce chemotherapy-induced hair loss

Today, the U.S. Food and Drug Administration cleared for marketing in the United States the first cooling cap to reduce hair loss (alopecia) in female breast cancer patients undergoing chemotherapy.

9 Dec 2015

UGA researchers identify biological markers for mental disorders

A team of researchers led by faculty at the University of Georgia has identified a number of biological markers that make it possible to classify mental disorders with greater precision. Their findings, published today in the American Journal of Psychiatry, may one day lead to improved diagnostics and treatments for those suffering from mental illness.

9 Dec 2015

Efficacy News and Research

Medication holds promise for protecting fertility and the body's defense system during chemotherapy

Social and emotional skills intervention can help young Syrian refugees heal psychological wounds

ESSA reports net loss of $11.5 million for year ended September 30, 2015

Ibrutinib ‘new standard’ for relapsed, refractory mantle cell lymphoma

BTG receives 510k clearance for LC Bead LUMI

Aural feedback can help people to clean their teeth more gently

Combination treatment provides effective one-two punch against prostate cancer

FDA approves Vistogard (uridine triacetate) for emergency treatment of chemotherapy overdose

Alecensa (alectinib) approved for treatment of people with advanced ALK-positive NSCLC

Early promise for pulmonary artery denervation in PAH patients

Role for carfilzomib in relapsed, refractory multiple myeloma treatment

Capecitabine increases disease-free survival for HER2-negative breast cancer patients

Study reveals why anti-hormone therapy tamoxifen works better in some women than others

Videregen-led TETRA consortium awarded EUR 6.8 million for pivotal Phase II trial of replacement trachea

Caregiver-implemented singing beneficial in early stages of dementia

New class of diabetes drugs differs in efficacy and safety profiles, shows new research

Boehringer Ingelheim begins SENSCIS study to investigate safety, efficacy of nintedanib in patients with SSc-ILD

Tetra begins human Phase 1 safety trials of BPN14770

FDA clears for marketing first cooling cap to reduce chemotherapy-induced hair loss

UGA researchers identify biological markers for mental disorders

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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