Cell Death News and Research

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Zentalis contributes $1 million to SU2C Catalyst program for research into targeted cancer therapeutics

Stand Up To Cancer and Zentalis Pharmaceuticals, Inc. today announced that Zentalis will contribute $1 million to the SU2C Catalyst program to support research that investigates the use of certain small molecule inhibitors for treating a variety of cancer types.

15 Mar 2022

Malaria drug could help treat chemotherapy-resistant head and neck cancers

A new study suggests that the malaria drug hydroxychloroquine inhibits pathways that drive resistance to the chemotherapy agent cisplatin in head and neck cancers and restores tumor-killing effects of cisplatin in animal models.

14 Mar 2022

Long-lasting immune activity in the airways may be the cause of persistent post-COVID-19 breathlessness

Long-lasting immune activity in the airways might be the cause of persistent breathlessness following COVID-19.

10 Mar 2022

'Post-apoptotic pro-metastatic cells' appear to be potential metastasis prevention targets

Researchers at UNIGE show that the experience of impending cell death within a primary tumor can lead to the development of pro-metastatic cells.

10 Mar 2022

Cedars-Sinai scientists identify potential new therapy for COVID-19

Investigators at Cedars-Sinai have identified a potential new therapy for COVID-19: a biologic substance created by reengineered human skin cells.

9 Mar 2022

Mechanical stress of confined migration makes cancer cells more aggressive

Squeezing through tight spaces makes cancer cells more aggressive and helps them evade cell death, shows a study published today in eLife.

9 Mar 2022

Low SARS-CoV-2 diabetogenicity found in infected human pancreatic cells in vitro

Researchers assessed the diabetogenic potential of SARS-CoV-2 in a single cell in vitro analysis on the pancreatic islet cells.

9 Mar 2022

New, highly promising strategy to overcome a key cause of cancer deaths

A research team led by scientists at Albert Einstein College of Medicine has devised a novel and highly promising strategy for overcoming a key cause of cancer deaths: the ability of cancer cells to thrive in the face of chemotherapy drugs designed to destroy them.

7 Mar 2022

Biologists reveal structure of newly discovered speargun-like molecular injection systems in bacteria

Biologists from ETH Zurich have discovered speargun-like molecular injection systems in two types of bacteria and have described their structure for the first time.

7 Mar 2022

Study uncovers new clues about the cellular processes that can lead to androgen deficiency

A laboratory study at the Miller School of Medicine's Desai Sethi Urology Institute has uncovered new clues about the cellular processes that can lead to deficiencies of androgens (male hormones) such as testosterone.

4 Mar 2022

T-cell cytokine and fatty acid work together to trigger a type of cell death

Researchers at the University of Michigan Rogel Cancer Center found that a cytokine, a category of protein that acts as messengers in the body, and a fatty acid can work together to trigger a type of cell death previously defined by studies with synthetic molecules.

4 Mar 2022

New micro-protein supports cell division and proliferation during nutrient scarcity

Researchers from the University of Eastern Finland and the University of Montreal (Canada) have discovered that a micro-protein, which they named Nrs1, supports cell division and proliferation when nutrients are scarce.

4 Mar 2022

Triple drug regimen proven effective against non-structural protein-1 of SARS-CoV-2

Researchers evaluated the synergistic activity of drugs acting against non-structural protein 1 of SARS-CoV-2 to decrease the viral infectivity.

2 Mar 2022

Study explores signature gut microbiome connection with immune checkpoint inhibitor response in advanced melanomas

Researchers from different countries performed a meta-analysis of real-world cross-cohorts and provided an association of the gut microbiome with immune checkpoint inhibitors response in patients with advanced melanomas.

2 Mar 2022

Targeting necroptosis using a necroptosis inhibitor lessens myositis-induced muscle weakness

A new study has suggested that treatment to target necroptosis in muscle fibers using a necroptosis inhibitor lessens myositis-induced muscle weakness as well as muscle cell death and inflammation in the muscles. This has been shown to be a promising strategy for treating polymyositis.

2 Mar 2022

Microorganisms hindering cancer therapy have more influence than the beneficial ones, study says

Melanoma patients receiving therapy that helps their immune system kill cancer cells respond to treatment differently depending on the types of microbes in their gut, and new research suggests the microorganisms hindering therapy have more influence than the beneficial ones.

28 Feb 2022

Advanced gene therapy may prevent severe loss of muscle mass in elderly people

Researchers at NTNU have managed to restore muscle function in older mice with muscle loss using advanced gene therapy. The hope is that this method might eventually be used on humans to prevent severe loss of muscle mass.

24 Feb 2022

Genetic analysis reveals eosinophilic colitis as a unique disease

A condition called eosinophilic colitis is distinct from other, similar eosinophilic gastrointestinal diseases and inflammatory bowel disease, according to a genetic analysis published in Gastroenterology.

24 Feb 2022

Study shows how certain RNA molecules control the repair of damaged DNA in cancer cells

A new study from Karolinska Institutet in Sweden shows how certain RNA molecules control the repair of damaged DNA in cancer cells, a discovery that could eventually give rise to better cancer treatments. The study is published today in the journal Nature Communications.

23 Feb 2022

Photoinactivating effect of visible light on viruses

The current literature study focused on visible light inactivation investigations of viruses.

23 Feb 2022

Cell Death News and Research

Zentalis contributes $1 million to SU2C Catalyst program for research into targeted cancer therapeutics

Malaria drug could help treat chemotherapy-resistant head and neck cancers

Long-lasting immune activity in the airways may be the cause of persistent post-COVID-19 breathlessness

'Post-apoptotic pro-metastatic cells' appear to be potential metastasis prevention targets

Cedars-Sinai scientists identify potential new therapy for COVID-19

Mechanical stress of confined migration makes cancer cells more aggressive

Low SARS-CoV-2 diabetogenicity found in infected human pancreatic cells in vitro

New, highly promising strategy to overcome a key cause of cancer deaths

Biologists reveal structure of newly discovered speargun-like molecular injection systems in bacteria

Study uncovers new clues about the cellular processes that can lead to androgen deficiency

T-cell cytokine and fatty acid work together to trigger a type of cell death

New micro-protein supports cell division and proliferation during nutrient scarcity

Triple drug regimen proven effective against non-structural protein-1 of SARS-CoV-2

Study explores signature gut microbiome connection with immune checkpoint inhibitor response in advanced melanomas

Targeting necroptosis using a necroptosis inhibitor lessens myositis-induced muscle weakness

Microorganisms hindering cancer therapy have more influence than the beneficial ones, study says

Advanced gene therapy may prevent severe loss of muscle mass in elderly people

Genetic analysis reveals eosinophilic colitis as a unique disease

Study shows how certain RNA molecules control the repair of damaged DNA in cancer cells

Photoinactivating effect of visible light on viruses

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

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