DNA Sequencing News and Research

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U-M ranks sixth among all medical schools in NIH funding

Research at the University of Michigan Medical School brought hundreds of millions of dollars into the state of Michigan in the last year - and could have a total economic impact of nearly $1.2 billion, new data show.

22 Nov 2011

Researchers discover more about function of muscle stem cells

An international team of researchers from Leeds, London and Berlin has discovered more about the function of muscle stem cells, thanks to next-generation DNA sequencing techniques.

20 Nov 2011

Budding yeast helps make useful predictions about the biology of individuals

It now only costs a few thousand Euros to sequence the genome of an individual human. However, for most of us, knowing our genome sequence would not be useful. Each human has more than 20 000 genes, and in each of us several thousand of these genes carry mutations.

16 Nov 2011

Leading alcohol researchers to discuss latest genetic findings at Loyola meeting

Leading alcohol researchers from the United States and Canada will discuss their latest findings at an all-day meeting Nov. 18 at Loyola University Chicago Stritch School of Medicine.

16 Nov 2011

New method to stack synthetic DNA and carbon nanotubes onto biosensor electrode

Purdue University scientists have developed a method for stacking synthetic DNA and carbon nanotubes onto a biosensor electrode, a development that may lead to more accurate measurements for research related to diabetes and other diseases.

16 Nov 2011

Mutations make Staph more resistant to antibiotics

Infectious diseases specialists from Austin Health are working closely with Microbiologists from the University of Melbourne to understand how Staph is becoming resistant to all antibiotic therapies.

11 Nov 2011

Genetic sequencing key to fundamentally understanding diseases

What started back in 2004 as a three-person start-up may well be on its way to becoming a multi-million euro success story. Advanced by a team of young Dutch scientists pushing disruptive biotech innovations onto the market, the SME FlexGen is attracting the attention of some key investors and demonstrating the added value that public support can offer to innovative SMES, with the Eurostars funding programme leading the way.

9 Nov 2011

Novel mathematical method reveals genetic distinction between individuals

At a time when profound gaps remain in our understanding of how one person's genes differ from another person's, developing accurate methods to interpret the human genome is essential to uncover population history, population relationships and the genetic basis of some of the most common diseases affecting society.

9 Nov 2011

Prefrontal cortex neurons from individuals with autism show changes in chromatin structures

Neurons in the prefrontal cortex of individuals with autism show changes at numerous sites across the genome, according to a study being published Online First by the Archives of General Psychiatry, one of the JAMA/Archives journals.

8 Nov 2011

Epigenetic alterations may play an important role in autism

Scientists at the University of Massachusetts Medical School are the first to map epigenetic changes in neurons from the brains of individuals with autism, providing empirical evidence that epigenetic alterations-changes in gene expression caused by mechanisms other than changes in the underlying DNA sequence-may play an important role in the disease.

8 Nov 2011

Vampire-like bacteria has potential to serve as living antibiotic

A vampire-like bacteria that leeches onto specific other bacteria - including certain human pathogens - has the potential to serve as a living antibiotic for a range of infectious diseases, a new study indicates.

1 Nov 2011

First report on how patterns of 5-hmC's distribution change in mouse brain during development

In 2009, the DNA alphabet expanded. Scientists discovered that an extra letter or "sixth nucleotide" was surprisingly abundant in DNA from stem cells and brain cells.

31 Oct 2011

Scientists discover Leishmania parasite with juggling chromosomes

Scientists found a deadly parasite with some of its chromosomes in duplicate, others in triplicate, while still others are present four or even five times. Moreover, the copy number varies between individuals. Such a bizarre occurrence has never before been found in nature, in any organism. As a rule, chromosomes should come in couples. The scientists, from the Institute of Tropical Medicine (ITG) and the Wellcome Trust Sanger Institute, made the striking discovery while deciphering the genetic code of a series of Leishmania-parasites.

29 Oct 2011

New discoveries on drug resistance in Leishmania

Two remarkable discoveries were today revealed by researchers into genome analysis of Leishmania parasites. These results uncovered a surprising level of variation at the genome structure level.

28 Oct 2011

New rapid method for detection of BRAF V600E gene in thyroid tissue

During surgical removal of thyroid tissue suspicious for cancer, fast, reliable, and cost-effective techniques are needed to analyze the resected tissue for biomarkers—including BRAF V600E, is a molecular biomarker for papillary thyroid cancer (PTC)—that can confirm the presence and type of cancer cells. Researchers have developed a new, rapid method for direct detection of the BRAF V600E gene in thyroid tissue without the need to purify DNA from tumor cells—high resolution melting analysis.

28 Oct 2011

BGI, UC Davis partner to create new sequencing facility in Sacramento

The University of California, Davis, and BGI, the world's largest genomic institute, based in China, have signed a historic agreement that will change the landscape of genomic sciences in California and the Western states, and foster critical breakthroughs in the areas of food security and human, animal and environmental health.

27 Oct 2011

NIST, CU develop novel low-power transport microchip

Researchers from the National Institute of Standards and Technology (NIST) and University of Colorado Boulder (CU) have developed a low-power microchip that uses a combination of microfluidics and magnetic switches to trap and transport magnetic beads. The novel transport chip may have applications in biotechnology and medical diagnostics.

20 Oct 2011

New sequencing method can identify genetic variants linked to ASD

Geneticists at Emory University School of Medicine have demonstrated a method that enables the routine amplification of all the genes on the X chromosome. The technology allows the rapid and highly accurate sequencing and identification of novel genetic variants affecting X chromosome genes.

19 Oct 2011

Scientists discover a way to accurately map typhoid outbreaks in the city

In the mid-nineteenth century, John Snow mapped cases of cholera in Soho, London, and traced the source of the outbreak to a contaminated water pump. Now, in a twenty-first century equivalent, scientists funded by the Wellcome Trust working in Kathmandu, Nepal, have combined the latest in gene sequencing technology and global positioning system (GPS) case localisation to map the spread of typhoid and trace its source.

18 Oct 2011

AzTE, Roche sign license agreement to develop revolutionary DNA sequencing system

Roche and Arizona Technology Enterprises (AzTE) announced today an agreement to license several technologies developed by Dr. Stuart Lindsay at the Biodesign Institute- at Arizona State University and Dr. Colin Nuckolls of the Columbia University Nanoscience Center for the development of a revolutionary DNA sequencing system.

12 Oct 2011