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AI trained on 9 trillion DNA letters predicts harmful mutations and designs new genomes

Scientists developed Evo 2, a large biological foundation model trained on about 9 trillion DNA base pairs that can analyse genomic sequences across bacteria, plants, and humans. The model predicts functional effects of genetic variants and can generate genome-scale DNA sequences, enabling new approaches to studying and designing biological systems.

5 Mar 2026

Targeted mRNA delivery restores sperm production and fertility in infertile mice

Researchers have found that targeted delivery of messenger RNA (mRNA) can restore sperm production and fertility in genetically infertile male mice.

5 Mar 2026

New AstroID database integrates clinical and genetic data for large-scale cancer studies

Researchers from the Johns Hopkins Kimmel Cancer Center and The Johns Hopkins University have created a novel database structure that allows investigators anywhere to more easily study multiple types of cancer data - including laboratory results, genetic sequencing and imaging data - in one setting.

5 Mar 2026

Researchers find novel path to treat Rett syndrome

A team of researchers at Texas Children's Duncan Neurological Research Institute (NRI) and Baylor College of Medicine report in Science Translational Medicine a potential new approach to treat Rett syndrome – offering early promise for a rare neurodevelopmental disorder that currently has no cure.

5 Mar 2026

As ICE moved in, Minnesotans set up a shadow medical system. It’s a lesson for other cities.

Gabi has big brown eyes, pigtails, and a genetic condition that makes her bones brittle. They fracture easily, leaving the 2-year-old in such pain that her mother quit her job cleaning offices to stay home and cradle her in the one-bedroom apartment they share with six relatives.

5 Mar 2026

Environmental swabs reveal hidden avian viral diversity

Scientists at Duke-NUS Medical School have found that viruses circulating in live poultry markets can be detected more effectively by sampling the surrounding environment than by testing individual birds. The study, published in Nature Communications, shows that environmental sampling can uncover a broader range of poultry viruses-including highly pathogenic avian influenza strains that traditional surveillance may miss.

5 Mar 2026

Experimental therapy dramatically reduces seizures in children with Dravet syndrome

A new experimental treatment for children with a hard-to-treat form of epilepsy is safe and can reduce seizures dramatically, helping them lead much healthier and happier lives, the findings of a UCL and Great Ormond Street Hospital-led international clinical trial show.

4 Mar 2026

Enhancing myelination may help sustain therapeutic effects of psychedelic-assisted PTSD treatment

Post-traumatic stress disorder (PTSD) is not only characterized by strongly encoded traumatic memories, but also by disrupted coordination across brain networks.

4 Mar 2026

Study offers new insight into the earliest steps of cataract formation

Cataracts are a leading cause of blindness worldwide and are considered a priority disease by the World Health Organization.

4 Mar 2026

Study sheds light on potential therapeutic strategies for post-traumatic osteoarthritis

Post-traumatic osteoarthritis often affects younger, active individuals and progresses quickly following ligament or cartilage injury.

4 Mar 2026

Nonadherence to COPD medication increases hospital admissions and mortality

Medication nonadherence among people with chronic obstructive pulmonary disease (COPD) is a result of affordability and lack of knowledge about medications, among other factors, and leads to increased exacerbations and faster lung function decline, according to two new studies.

4 Mar 2026

Microbial taxa more likely to be found in people with dyslipidemia

Before the onset of cardiovascular disease symptoms, people often develop dyslipidemia, or abnormal levels of lipids in the blood.

4 Mar 2026

Study uncovers a biological cause for persistent taste loss after COVID-19

Some individuals have experienced a loss of taste long after a COVID-19 infection has subsided. Researchers from the Swedish University of Agricultural Sciences, Uppsala University and the University of Colorado have now shown that this may be due to a disruption in taste cells that would otherwise give rise to experiences of sweet, bitter or umami.

4 Mar 2026

New HIV-seq tool advances understanding of persistent viral reservoirs

For people living with human immunodeficiency virus (HIV), life-saving antiretroviral therapy keeps their HIV-infected immune cells from making new copies of the virus, preventing illness and transmission.

3 Mar 2026

New strategy targets Porphyromonas gingivalis without harming healthy microbes

For years, treating gum disease has meant scraping away plaque, cutting out damaged tissue or turning to antibiotics that kill bacteria indiscriminately.

3 Mar 2026

Are socially isolated people more likely to develop cancer? Study of 350,000 adults explores the risk

A large UK Biobank study of more than 350,000 adults found that social isolation, but not loneliness alone, was associated with a modest increase in overall cancer risk during over 11 years of follow-up. The association was stronger in women and appeared partly linked to socioeconomic disadvantage, unhealthy behaviors, and inflammatory processes.

3 Mar 2026

New collaboration explores familial inflammatory bowel disease in Saudi Arabia

Mount Sinai and King Saud University Medical City in Riyadh, Saudi Arabia, today announced a three-year collaboration aimed at better understanding why inflammatory bowel disease (IBD) runs in some Saudi families, and how that knowledge can lead to risk ascertainment, earlier diagnosis and more personalized treatment options.

3 Mar 2026

Puberty reshapes DNA to worsen or reverse insulin resistance

This study uncovers epigenetic changes during puberty that correlate with insulin resistance, offering insights into childhood obesity and metabolic risk.

3 Mar 2026

New research on two million people quantifies how genetic risks overlap across diagnoses

A sweeping new peer-reviewed study published in Genomic Psychiatry has introduced a concept that could reshape how psychiatrists and geneticists think about mental illness: genetic specificity.

3 Mar 2026

Mandated cCMV screening improves early identification of infant hearing loss

A new retrospective cohort study examining the impact of Minnesota's first-in-the-nation mandated universal newborn screening for congenital cytomegalovirus (cCMV) shows that universal screening significantly decreased the age at first audiology visit and increased identification of mild hearing loss in infants.

2 Mar 2026

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Genetic News and Research

AI trained on 9 trillion DNA letters predicts harmful mutations and designs new genomes

Targeted mRNA delivery restores sperm production and fertility in infertile mice

New AstroID database integrates clinical and genetic data for large-scale cancer studies

Researchers find novel path to treat Rett syndrome

As ICE moved in, Minnesotans set up a shadow medical system. It’s a lesson for other cities.

Environmental swabs reveal hidden avian viral diversity

Experimental therapy dramatically reduces seizures in children with Dravet syndrome

Enhancing myelination may help sustain therapeutic effects of psychedelic-assisted PTSD treatment

Study offers new insight into the earliest steps of cataract formation

Study sheds light on potential therapeutic strategies for post-traumatic osteoarthritis

Nonadherence to COPD medication increases hospital admissions and mortality

Microbial taxa more likely to be found in people with dyslipidemia

Study uncovers a biological cause for persistent taste loss after COVID-19

New HIV-seq tool advances understanding of persistent viral reservoirs

New strategy targets Porphyromonas gingivalis without harming healthy microbes

Are socially isolated people more likely to develop cancer? Study of 350,000 adults explores the risk

New collaboration explores familial inflammatory bowel disease in Saudi Arabia

Puberty reshapes DNA to worsen or reverse insulin resistance

New research on two million people quantifies how genetic risks overlap across diagnoses

Mandated cCMV screening improves early identification of infant hearing loss

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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