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New mechanism may explain neurons shrinking in Huntington's disease

A hallmark of neurodegenerative diseases like Huntington's is the progressive death of nerve cells in the brain. The cells don't die quickly, though. They first start to disconnect from each other because their neurites -- long finger-like extensions that make connections all through the brain -- become smaller.

25 Dec 2018

New vaccine shows promise against chikungunya virus

A live vaccine genetically engineered from a common measles vaccine promises to be effective against the chikungunya virus. Such is the central finding of a recently completed Phase II trial now published in the prestigious journal "The Lancet".

21 Dec 2018

New genetically modified common houseplant purifies air around it

We like to keep the air in our homes as clean as possible, and sometimes we use HEPA air filters to keep offending allergens and dust particles at bay.

20 Dec 2018

Genetically modified houseplant can efficiently detoxify indoor air

Our homes are supposed to be safe havens from the outside world. However, studies have shown that household air is more polluted than either office or school air, exposing children and home workers to higher levels of carcinogens than the general population.

19 Dec 2018

Gut microbiome plays role in immune system regulation, study finds

Scientist have long known that bacteria in the intestines, also known as the microbiome, perform a variety of useful functions for their hosts, such as breaking down dietary fiber in the digestive process and making vitamins K and B7.

19 Dec 2018

Mouse study uncovers how marijuana may damage some adolescent brains

In a study of adolescent mice with a version of a gene linked to serious human mental illnesses, Johns Hopkins Medicine researchers say they have uncovered a possible explanation for how marijuana may damage the brains of some human teens.

18 Dec 2018

Russian scientists identify molecular 'switch' that could be target for treatment of allergic asthma

A team of Russian scientists identified the role of the interleukin-6 molecule in the development of allergic asthma. Now it can be a new target for the treatment of this disease. The results are published in Frontiers in Immunology.

17 Dec 2018

Experimental HIV vaccine strategy works in non-human primates, research shows

For more than 20 years, scientists at Scripps Research have chipped away at the challenges of designing an HIV vaccine. Now new research, published in Immunity, shows that their experimental vaccine strategy works in non-human primates.

14 Dec 2018

Exercise-induced hormone activates cells critical for bone remodeling in mice

Exercise has been touted to build bone mass, but exactly how it actually accomplishes this is a matter of debate. Now, researchers show that an exercise-induced hormone activates cells that are critical for bone remodeling in mice.

14 Dec 2018

Diets containing GM maize have no harmful effects on health or metabolism of rats

For six months, rats were fed a diet containing either GM maize (MON 810 or NK603) or non-GM maize, in varying concentrations.

14 Dec 2018

Genetically modified pigs could limit replication of classical swine fever virus, study shows

Researchers have developed genetically modified pigs that are protected from classical swine fever virus, according to a study published December 13 in the open-access journal PLOS Pathogens by Hongsheng Ouyang of Jilin University, and colleagues.

14 Dec 2018

Johns Hopkins researchers identify molecular causes of necrotizing enterocolitis in preemies

Using a mouse model of necrotizing enterocolitis -- a potentially fatal condition that causes a premature infant's gut to suddenly die -- researchers at Johns Hopkins say they have uncovered the molecular causes of the condition and its associated brain injury.

14 Dec 2018

Alzheimer's could possibly be spread via contaminated neurosurgery

Researchers have found that surgical instruments used for neurosurgery could get contaminated by the altered brain proteins that are seen in Alzheimer’s disease. These instruments are capable of spreading the condition if not treated or decontaminated properly before reuse. The study results were published in the latest issue of the journal Nature.

14 Dec 2018

Study provides new insights into molecular mechanisms underlying role of amyloid in Alzheimer's disease

A UCL-led study has confirmed that some vials of a hormone used in discontinued medical treatments contained seeds of a protein implicated in Alzheimer's disease, and are able to seed amyloid pathology in mice.s

14 Dec 2018

New discovery will improve the safety and predictability of CRISPR

Scientists have discovered a simple set of rules that can be used to precisely predict how DNA will be modified by the CRISPR gene editing technique.

13 Dec 2018

Study: Loss of tight junction barrier protein results in gastric cancer development

Tight junctions are multi-protein complexes that serve as barriers in epithelial tissues such as the skin or lining of the gut. Loss of a specific tight junction barrier protein, claudin 18, occurs in the majority of gastric cancer patients and is correlated with poor prognosis in patients with advanced gastric cancer.

13 Dec 2018

New method to visualize small-molecule interactions inside cells

Like people in a large company, proteins in cells constantly interact with each other to perform various jobs. To develop new disease therapies, researchers are trying to control these interactions with small-molecule drugs that cause specific proteins to associate more or less with their "coworkers."

13 Dec 2018

Targeting biochemical pathway may lead to new therapies for alleviating symptoms of anxiety disorders

According to some estimates, up to one in three people around the world may experience severe anxiety in their lifetime.

12 Dec 2018

SLU researchers explore how fetal exposure to inflammation can alter immunity in newborns

Saint Louis University researchers are studying how fetal exposure to inflammation can alter immune responses after birth.

12 Dec 2018

Researchers develop biotechnological tool to produce antifungal proteins in plants

Researchers from the Spanish Research Council at the Centre for Research in Agricultural Genomics and the Institute for Plant Molecular and Cellular Biology, in collaboration with the IATA, have developed a biotechnological tool to produce, in a very efficient manner, antifungal proteins in plants.

10 Dec 2018

Genetic Engineering News and Research

New mechanism may explain neurons shrinking in Huntington's disease

New vaccine shows promise against chikungunya virus

New genetically modified common houseplant purifies air around it

Genetically modified houseplant can efficiently detoxify indoor air

Gut microbiome plays role in immune system regulation, study finds

Mouse study uncovers how marijuana may damage some adolescent brains

Russian scientists identify molecular 'switch' that could be target for treatment of allergic asthma

Experimental HIV vaccine strategy works in non-human primates, research shows

Exercise-induced hormone activates cells critical for bone remodeling in mice

Diets containing GM maize have no harmful effects on health or metabolism of rats

Genetically modified pigs could limit replication of classical swine fever virus, study shows

Johns Hopkins researchers identify molecular causes of necrotizing enterocolitis in preemies

Alzheimer's could possibly be spread via contaminated neurosurgery

Study provides new insights into molecular mechanisms underlying role of amyloid in Alzheimer's disease

New discovery will improve the safety and predictability of CRISPR

Study: Loss of tight junction barrier protein results in gastric cancer development

New method to visualize small-molecule interactions inside cells

Targeting biochemical pathway may lead to new therapies for alleviating symptoms of anxiety disorders

SLU researchers explore how fetal exposure to inflammation can alter immunity in newborns

Researchers develop biotechnological tool to produce antifungal proteins in plants

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