Lymph Nodes News and Research

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Study: Recurrence of SCCOP may differ in HPV-positive and HPV-negative patients

Patients with HPV-positive squamous cell carcinoma of the oropharynx (SCCOP) had a longer time to development of distant metastasis (DM) after initial treatment, and had more metastatic sites in more atypical locations compared to HPV-negative patients, according to research presented today at the 2014 Multidisciplinary Head and Neck Cancer Symposium.

21 Feb 2014

Reduction of RT to IB lymph nodes may result in better salivary function in head, neck cancer patients

For head and neck cancer patients undergoing radiation therapy, a reduction in the amount of radiation treatment volume to the submandibular (level IB) lymph nodes resulted in better patient-reported salivary function, according to research presented today at the 2014 Multidisciplinary Head and Neck Cancer Symposium.

21 Feb 2014

New approach for delivering vaccines and for stimulating body's immune system to attack tumors

Many vaccines, including those for influenza, polio, and measles, consist of a killed or disabled version of a virus. However, for certain diseases, this type of vaccine is ineffective, or just too risky.

18 Feb 2014

Study affirms new standard for detecting melanoma metastasis to the lymph nodes

Long-term research that was initiated at UCLA's Jonsson Comprehensive Cancer Center on lymphatic mapping and sentinel-node biopsy, techniques for detecting the earliest spread (metastasis) of melanoma, the deadliest form of skin cancer, has confirmed that these techniques significantly prolong patients' disease-free and melanoma-specific survival over the traditional observational "watch and wait" techniques.

14 Feb 2014

Elusive progenitor cells that give rise to ILCs identified in fetal liver and bone marrow of mice

The elusive progenitor cells that give rise to innate lymphoid cells-a recently discovered group of infection-fighting white blood cells-have been identified in fetal liver and adult bone marrow of mice, researchers from the University of Chicago report early online in the journal Nature.

14 Feb 2014

Cook Medical introduces first endobronchial ultrasound needle in the U.S

Cook Medical is introducing the first endobronchial ultrasound (EBUS) needle in the U.S. that can acquire histological samples. The EchoTip ProCore Endobronchial Ultrasound Needle gives physicians the ability to retrieve both cell and tissue samples from lymph nodes or tumors in the pulmonary area.

From COOK MEDICAL INC. 12 Feb 2014

Research: SSeCKS/AKAP12 gene key inhibitor of prostate cancer metastasis

New evidence reported by researchers at Roswell Park Cancer Institute (RPCI) lends support to the hypothesis that the SSeCKS/AKAP12 gene is a key inhibitor of prostate cancer metastasis.

4 Feb 2014

Findings could improve clinical management of patients with breast tissue abnormalities

Contrary to existing understanding, long-term follow-up of patients with two types of breast tissue abnormalities suggests that both types of abnormalities have the same potential to progress to breast cancer, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research. Findings from this study could improve clinical management of patients with breast tissue abnormalities.

30 Jan 2014

Professor receives ALSF grant to develop cancer vaccine technology that help children to have healthy life

In 2004, a form of cancer known as neuroblastoma claimed the life of Alexandra (Alex) Scott, a little girl who gained national attention for using her lemonade stand to raise money for cancer research.

8 Jan 2014

Perioperative analgesia may improve prostate cancer outcomes

Neuraxial analgesia added to general anesthesia for radical retropubic prostatectomy may lead to improved oncologic outcomes in prostate cancer, US researchers have found.

6 Jan 2014

FDA grants orphan drug designation for DiaVacs' type 1 diabetes mellitus therapy

DiaVacs, Inc. announced today that the Office of Orphan Products Development of the Food and Drug Administration has granted orphan drug designation for the company's type 1 diabetes mellitus (T1DM) therapy.

6 Jan 2014

Navidea seeks FDA approval for marketing Lymphoseek Injection for SLN detection

Navidea Biopharmaceuticals, Inc., a biopharmaceutical company focused on precision diagnostic radiopharmaceuticals, announced today that it has submitted a Supplemental New Drug Application with the U.S. Food and Drug Administration seeking approval for the marketing and sale of Lymphoseek (technetium 99m tilmanocept) Injection for sentinel lymph node detection in patients with head and neck cancer, an indication for which Lymphoseek was also granted Fast Track designation earlier this month.

17 Dec 2013

Adding drug to presurgery chemotherapy improves results for women with triple-negative breast cancer

The I-SPY 2 trial, an innovative, multidrug, phase II breast cancer trial, has yielded positive results with the first drug to complete testing in the trial. Adding the chemotherapy carboplatin and the molecularly targeted drug veliparib to standard presurgery chemotherapy improved outcomes for women with triple-negative breast cancer, according to results from the I-SPY 2 trial presented here at the 2013 San Antonio Breast Cancer Symposium, held Dec. 10-14.

16 Dec 2013

Bisphosphonate zoledronate treatment not effective in women with chemoresistant breast cancer

Treatment with the bisphosphonate zoledronate did not improve outcomes for women with chemoresistant breast cancer, according to initial results of a phase III clinical trial presented here at the 2013 San Antonio Breast Cancer Symposium, held Dec. 10-14.

14 Dec 2013

Protein in Salmonella inactivates mast cells that fight against bacteria

A protein in Salmonella inactivates mast cells -- critical players in the body's fight against bacteria and other pathogens -- rendering them unable to protect against bacterial spread in the body, according to researchers at Duke Medicine and Duke-National University of Singapore (Duke-NUS).

13 Dec 2013

New treatment needed for women with HER2- and hormone receptor-positive breast cancer with PIK3CA mutation

Women with breast cancer characterized by high levels of the protein HER2 and hormone receptors gained much less benefit from presurgery treatment with chemotherapy and HER2-targeted therapies if their cancer had one or more mutations in the PIK3CA gene, according to results presented here at the 2013 San Antonio Breast Cancer Symposium, held Dec. 10-14.

12 Dec 2013

Results from NeoALTTO trial to be presented at 2013 San Antonio Breast Cancer Symposium

Results from the initial analysis of event-free and overall survival for patients enrolled in the randomized, phase III Neoadjuvant Lapatinib and/or Trastuzumab Treatment Optimization trial are to be presented here at the 2013 San Antonio Breast Cancer Symposium, held Dec. 10-14.

12 Dec 2013

Study: Taxol and Herceptin highly effective for lower-risk breast cancer patients

A remarkable 98.7 percent of certain lower-risk breast cancer patients were cancer free for at least three years after taking a combination of the drugs Herceptin and Taxol, a study has found.

12 Dec 2013

Tumor-infiltrating lymphocytes may be good biomarker of response to trastuzumab in breast cancer

Women with HER2-positive breast cancer who had the highest levels of immune cells in their tumors gained the most benefit from presurgery treatment with chemotherapy and trastuzumab, according to results presented here at the 2013 San Antonio Breast Cancer Symposium, held Dec. 10-14.

12 Dec 2013

Women with HER2+ breast tumors who receive combination therapy unlikely to have cancer recur

In a new study, women with relatively small, HER2-positive breast tumors who received a combination of lower-intensity chemotherapy and a targeted therapy following surgery or radiation therapy were very unlikely to have the cancer recur within a few years of treatment, investigators at Dana-Farber Cancer Institute and other research centers will report at the 2013 San Antonio Breast Cancer Symposium.

12 Dec 2013

Lymph Nodes News and Research

Study: Recurrence of SCCOP may differ in HPV-positive and HPV-negative patients

Reduction of RT to IB lymph nodes may result in better salivary function in head, neck cancer patients

New approach for delivering vaccines and for stimulating body's immune system to attack tumors

Study affirms new standard for detecting melanoma metastasis to the lymph nodes

Elusive progenitor cells that give rise to ILCs identified in fetal liver and bone marrow of mice

Cook Medical introduces first endobronchial ultrasound needle in the U.S

Research: SSeCKS/AKAP12 gene key inhibitor of prostate cancer metastasis

Findings could improve clinical management of patients with breast tissue abnormalities

Professor receives ALSF grant to develop cancer vaccine technology that help children to have healthy life

Perioperative analgesia may improve prostate cancer outcomes

FDA grants orphan drug designation for DiaVacs' type 1 diabetes mellitus therapy

Navidea seeks FDA approval for marketing Lymphoseek Injection for SLN detection

Adding drug to presurgery chemotherapy improves results for women with triple-negative breast cancer

Bisphosphonate zoledronate treatment not effective in women with chemoresistant breast cancer

Protein in Salmonella inactivates mast cells that fight against bacteria

New treatment needed for women with HER2- and hormone receptor-positive breast cancer with PIK3CA mutation

Results from NeoALTTO trial to be presented at 2013 San Antonio Breast Cancer Symposium

Study: Taxol and Herceptin highly effective for lower-risk breast cancer patients

Tumor-infiltrating lymphocytes may be good biomarker of response to trastuzumab in breast cancer

Women with HER2+ breast tumors who receive combination therapy unlikely to have cancer recur

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