Mouse Model News and Research

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Study suggests SARS-CoV-2 is likely to only infect placental mammals

Researchers perform ontological and taxonomical analysis of human coronavirus hosts.

9 Feb 2023

Researchers find possible genetic basis and mouse model for nonalcoholic steatohepatitis

A mutant or damaged gene may be a cause of a severe, mysterious form of nonalcoholic fatty liver disease, University of Illinois Urbana-Champaign researchers have found.

9 Feb 2023

Inhalable powder could protect lungs and airways from viral invasion

Researchers have developed an inhalable powder that could protect lungs and airways from viral invasion by reinforcing the body's own mucosal layer.

9 Feb 2023

Researchers find a way to block anaphylaxis caused by peanut allergies

Researchers from Indiana University School of Medicine have found a way to block anaphylaxis caused by peanut allergies.

9 Feb 2023

New strategies to beat rare tumors of the adrenal gland

Only one in 100,000 people suffer from a pheochromocytoma, a tumor of the adrenal gland. If the tumor has already metastasized, a radioactive compound can be used to detect malignant cells that have spread to other parts of the body, and to irradiate them from the inside.

9 Feb 2023

High-fat diet allows the immune system to eliminate a parasitic worm from the intestine

Scientists have discovered that a high-fat diet allows the immune system to eliminate a parasitic worm which is a major cause of death and illness in the developing world.

7 Feb 2023

Researchers identify a new genetic risk factor for age-related macular degeneration

Researchers at Tel Aviv University identified a new genetic risk factor for the complex eye disease AMD (Age-related Macular Degeneration), a leading cause for loss of eyesight at an advanced age.

6 Feb 2023

Study reveals a vulnerability of macrophages that contributes to chronic inflammatory diseases

Macrophages are cells of the immune system that, in addition to playing an essential role in the early response to microbial infection, also regulate tissue function and inflammation.

3 Feb 2023

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

A research team from LKS Faculty of Medicine, the University of Hong Kong (HKUMed) discovered that somatic deletion of a tumor suppressor gene AKTIP promotes luminal breast cancer development and resistance to endocrine therapy.

3 Feb 2023

The human body develops strategies to prevent the immune response from overshooting its mark

The signaling molecules of the immune system should trigger a response only where necessary. To prevent a life-threatening spread to the rest of the body, connective tissue can absorb these molecules like a sponge.

3 Feb 2023

U of A researcher one step closer to demonstrating the potential of brain molecule to halt MS

A University of Alberta researcher is one step closer to demonstrating the potential of a brain molecule called fractalkine to halt and even reverse the effects of multiple sclerosis and other neurodegenerative diseases.

1 Feb 2023

Focused-ultrasound-mediated liquid biopsy improves detection of neurodegeneration biomarkers

Several progressive neurodegenerative disorders, including Alzheimer's disease, are defined by having tau proteins in the brain.

31 Jan 2023

New research changes the paradigm of how people think about graft-versus-host disease

New research challenges the prevailing hypothesis for how donor stem cell grafts cause graft-versus-host disease, or GVHD, and offers an alternative model that could guide development of novel therapies.

30 Jan 2023

Scientists Develop a Cancer Vaccine to Simultaneously Kill and Prevent Brain Cancer

Dual-action cell therapy engineered to eliminate established tumors and train the immune system to eradicate primary tumor and prevent cancer’s recurrence.

30 Jan 2023

Study reveals the inevitability of Zika virus dumbbell-1 structure for viral pathogenesis

In a recent study posted to the bioRxiv* preprint server, researchers designed two dumbbell-1 (DB-1) mutant Zika virus (ZIKV) infectious clones termed ZIKV-TL.PK and ZIKV-p.2.5’.

26 Jan 2023

Altered gut microbiome plays a major role in the progression of endometriosis in animal model

About 196 million women worldwide suffer from endometriosis, a condition that typically causes pelvic pain and infertility.

25 Jan 2023

Researchers discover the gene responsible for radiation resistance in mutant IDH1 glioma

It's a good news, bad news story. Patients whose brain tumors have a mutated enzyme called IDH1 typically live longer than those without the mutation.

24 Jan 2023

Modulating the lipid composition to treat bronchial asthma

Bronchial asthma, a chronic inflammatory disease of the airways that is reversible in certain cases, usually presents with cough, difficulty of breathing, and wheezing.

24 Jan 2023

Aston University scientists team up with Isterian Biotech to develop novel drugs to treat fibrotic diseases

Aston University scientists are working with start-up company, Isterian Biotech, part of Cambrian BioPharma, to develop novel drugs to treat fibrotic diseases such as lung disease.

23 Jan 2023

Study analyzes how immunological memory gets generated and maintained

Scientists have long sought to better understand the human body's immune responses that occur during various diseases, including cancer and inflammatory diseases.

23 Jan 2023

Mouse Model News and Research

Study suggests SARS-CoV-2 is likely to only infect placental mammals

Researchers find possible genetic basis and mouse model for nonalcoholic steatohepatitis

Inhalable powder could protect lungs and airways from viral invasion

Researchers find a way to block anaphylaxis caused by peanut allergies

New strategies to beat rare tumors of the adrenal gland

High-fat diet allows the immune system to eliminate a parasitic worm from the intestine

Researchers identify a new genetic risk factor for age-related macular degeneration

Study reveals a vulnerability of macrophages that contributes to chronic inflammatory diseases

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

The human body develops strategies to prevent the immune response from overshooting its mark

U of A researcher one step closer to demonstrating the potential of brain molecule to halt MS

Focused-ultrasound-mediated liquid biopsy improves detection of neurodegeneration biomarkers

New research changes the paradigm of how people think about graft-versus-host disease

Scientists Develop a Cancer Vaccine to Simultaneously Kill and Prevent Brain Cancer

Study reveals the inevitability of Zika virus dumbbell-1 structure for viral pathogenesis

Altered gut microbiome plays a major role in the progression of endometriosis in animal model

Researchers discover the gene responsible for radiation resistance in mutant IDH1 glioma

Modulating the lipid composition to treat bronchial asthma

Aston University scientists team up with Isterian Biotech to develop novel drugs to treat fibrotic diseases

Study analyzes how immunological memory gets generated and maintained

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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