Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Study documents the first case of Down syndrome in Neandertals

A new study published by an international multidisciplinary team of researchers including faculty at Binghamton University, State University of New York, documents the first case of Down syndrome in Neandertals and reveals that they were capable of providing altruistic care and support for a vulnerable member of their social group.

26 Jun 2024

Nonhuman primate model reveals early-stage Alzheimer’s disease progression

Research in nonhuman primates is opening the possibility of testing treatments for the early stages of Alzheimer’s and similar diseases, before extensive brain cell death and dementia set in.

26 Jun 2024

Human milk banks improve infant health but can't fully replace mother's milk

Scientists investigate human milk banks and their impact on infant health, highlighting differences between donated and maternal milk in gut microbiota and development.

25 Jun 2024

Weill Cornell Medicine receives $1.5M grant to predict prostate cancer bone metastasis

Weill Cornell Medicine received a $1.5 million grant from the U.S. Department of Defense Prostate Cancer Research Program to develop new approaches for predicting the spread of cancer cells to the bone in men with prostate cancer, using tumor samples taken at early stages of the disease.

25 Jun 2024

Single-image 3D modeling of the colon can enable rapid disease diagnosis

Using just a single image taken by a capsule endoscopy camera, scientists have succeeded in creating a three-dimensional model of the colon. This new method provides much better images and can help specialists detect disease more rapidly.

25 Jun 2024

Open-source platform enables high-definition spatial transcriptomics

An open-source platform developed by researchers in Nikolaus Rajewsky's lab at the Max Delbrück Center creates molecular maps from patient tissue samples with subcellular precision, enabling detailed study and potentially enhancing routine clinical pathology. The study was published in "Cell."

25 Jun 2024

Beyond genes, new research explores mechanics and calcium signaling

Using animals to study heart disease doesn't always translate well to human health outcomes, and human heart cells available for research don't work outside the human body.

25 Jun 2024

WEHI study reveals new methods in detecting necroptosis

Fully automated diagnostic techniques, including liquid handling robots, are poised to improve the lives of millions of people living with inflammatory diseases worldwide.

24 Jun 2024

New study in rhesus macaques offers early intervention window for Alzheimer's

Research in nonhuman primates is opening the possibility of testing treatments for the early stages of Alzheimer's and similar diseases, before extensive brain cell death and dementia set in.

24 Jun 2024

Researchers win $2.78 million grant to harness AI for precision treatment in rectal cancer

With a new five-year, $2.78 million grant from the National Institutes of Health and National Cancer Institute, researchers at Case Western Reserve University(CWRU), Cleveland Clinic and University Hospitals (UH) will use artificial intelligence (AI) to better treat rectal cancer patients.

24 Jun 2024

Study reveals metabolic syndrome's impact on brain volume and cognitive function

Associations between metabolic syndrome (MetS) and cognitive and neuroimaging outcomes in dementia-free adults.

24 Jun 2024

JAK inhibitor ruxolitinib enhances immunotherapy in Hodgkin lymphoma patients

Checkpoint inhibitor therapies can be thought of as the molecular "brake release" for the immune system.

20 Jun 2024

One copy of the Christchurch variant may confer protection against familial Alzheimer's disease

A scientific story that began with a discovery in just one extraordinary patient is now panning out. In 2019, an international team that included researchers from two Mass General Brigham hospitals - Mass Eye and Ear and Massachusetts General Hospital (MGH) - reported on the case of a patient who did not develop cognitive impairment until her late 70s, despite being part of a family at extremely high genetic risk for developing early-onset Alzheimer's disease.

20 Jun 2024

Study shows effectiveness of treating pancreatic cancer patients with chemotherapy before surgery

A new study published today in JAMA Network Open by an international cohort of researchers provides the latest data on the effectiveness of treating pancreatic cancer patients with chemotherapy (with or without radiation therapy) before surgery to remove a tumor.

19 Jun 2024

NTU Singapore study reveals high trust in AI among gastroenterologists

Artificial intelligence (AI) has permeated many aspects of medicine, with promises of accurate diagnoses, better management decisions, and improved outcomes for both patients and the healthcare system.

18 Jun 2024

Discovery of mobile regulatory T cells could revolutionize disease treatment

Scientists at the University of Cambridge have discovered that a type of white blood cell - called a regulatory T cell - exists as a single large population of cells that constantly move throughout the body looking for, and repairing, damaged tissue.

18 Jun 2024

Blood test identifies specific pathologies in frontotemporal dementia, ALS, and PSP

In a study with 991 adults, scientists at DZNE show that the most common forms of frontotemporal dementia (FTD) as well as the neurological diseases amyotrophic lateral sclerosis (ALS) and progressive supranuclear palsy (PSP) can be recognized by blood testing.

18 Jun 2024