B Cell News and Research

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Autoantibody found to cause schizophrenia-like behaviors in mice

Schizophrenia is a disorder that affects how people act, think, and perceive reality. It is often very difficult to treat because it has many different causes and symptoms.

6 Jun 2022

Three-drug therapy with autologous stem cell transplant improves progression-free survival for multiple myeloma patients

Patients with multiple myeloma who have been treated with a three-drug combination therapy have a growing number of choices for subsequent treatment. Results of a new study led by researchers at Dana-Farber Cancer Institute can help patients and their physicians weigh benefits and risks of each option.

6 Jun 2022

New nanoparticles may pave the way for development of clinical sepsis therapy

Sepsis, the body's overreaction to an infection, affects more than 1.5 million people and kills at least 270,000 every year in the U.S. alone.

6 Jun 2022

MIT researchers identify components of mucus that can inhibit fungal infections

Candida albicans is a yeast that often lives in the human digestive tract and mouth, as well as urinary and reproductive organs.

6 Jun 2022

Curia Adopts the Berkeley Lights Platform to Expand its Antibody Discovery Capabilities

Berkeley Lights, Inc. (Nasdaq: BLI), a leader in digital cell biology, and Curia, formerly AMRI, a leading contract research, development and manufacturing organization (CDMO), today announced Curia’s adoption of The Beacon® Optofluidic system and workflows from Berkeley Lights to accelerate and expand its antibody-based drug discovery capabilities.

From Bruker Cellular Analysis 6 Jun 2022

Persistence of viral RNA following acute infection

Professor Diane Griffin from the Johns Hopkins Bloomberg School of Public Health, USA, has recently explained the persistence mechanism of viral RNA in the human body after clinical recovery from acute infection.

6 Jun 2022

Study confirms the benefits of 'bridge therapy' for some children with high-risk neuroblastoma

Approximately half of children with neuroblastoma - a childhood cancer that develops from immature nerve cells - have a form that indicates a high likelihood of recurrence.

6 Jun 2022

New trial examines the effectiveness of combination immunotherapy for platinum-resistant ovarian cancer

A new clinical trial studying the effectiveness of a combination of immunotherapy treatments could be more effective for patients with ovarian cancer who are resistant to traditional interventions.

6 Jun 2022

Trial of peptide-centered SARS-CoV-2 T-cell activator in B-cell deficient individuals

A recent phase 1/2 study under review at the Nature Portfolio journal and posted to the Research Square* preprint server demonstrated that a peptide-centered severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) T-cell activator, CoVac-1, was efficient in B-cell deficient people.

6 Jun 2022

Taking everolimus post-surgery can improve outcomes in patients with high-risk renal cell carcinoma

In a study of patients with high-risk renal cell carcinoma, those who took the drug everolimus daily for up to one year after surgery lived longer without their disease returning (recurrence-free survival, or RFS) than those who did not take everolimus, although the results narrowly missed the clinical trial's prespecified level for statistical significance.

4 Jun 2022

Using DNA droplets for early disease detection

Aqueous droplet formation by liquid-liquid phase separation (or coacervation) in macromolecules is a hot topic in life sciences research.

3 Jun 2022

Researchers identify predictive biomarkers to fight against non-small cell lung cancer

In a recent study, researchers at the University of Missouri are identifying new minimally invasive biomarkers to develop a blood test for early detection of non-small cell lung cancer (NSCLC), one of two main types of lung cancer.

3 Jun 2022

$New combination of drugs increases survival time for some patients with refractory lung cancer$

New combination of drugs increases survival time for some patients with refractory lung cancer

A combination of the drugs ramucirumab and pembrolizumab reduced risk of death by 31% compared with the standard of care in patients with advanced non-small cell lung cancer that had progressed on prior immunotherapy.

3 Jun 2022

Study: Nearly 43% of patients with KRAS-mutated lung cancer respond to experimental drug adagrasib

Nearly 43% of patients with non-small cell lung cancer (NSCLC) whose lung cancers harbored a specific KRAS mutation responded to the experimental drug adagrasib, and the targeted agent also showed activity against lesions in the brain that metastasized from the lung tumors, according to results of a study led by Dana-Farber Cancer Institute investigators.

3 Jun 2022

Combinations of multiple genetic factors play a role in the broad spectrum of autism

Autism Spectrum Disorder (ASD) is referred to as a "spectrum" because clinical features of ASD range from mild social impairments in some people to severe intellectual disability or epilepsy in others.

3 Jun 2022

Computer vision tool effectively distinguishes rheumatoid arthritis from osteoarthritis in joint tissue

A new study led by Hospital for Special Surgery investigators in New York City has found that their computer vision tool effectively distinguishes rheumatoid arthritis (RA) from osteoarthritis (OA) in joint tissue taken from patients who underwent total knee replacement (TKR).

3 Jun 2022

Epidemiology and the public health response of monkeypox

Monkeypox is a zoonotic disease, i.e. it can be transmitted between animals and humans via direct or indirect contacts.

3 Jun 2022

Steady-state DNA motion allows cells to conduct housekeeping tasks under similar nuclear environments

Researchers in Japan have discovered that the local DNA motion inside of human cells remains steady throughout interphase, where the cell grows and replicates its DNA for cell division.

3 Jun 2022

Ibrutinib plus chemoimmunotherapy prolonged progression-free survival in previously untreated mantle cell lymphoma patients

Combination chemoimmunotherapy with the Bruton's tyrosine kinase (BTK) inhibitor ibrutinib demonstrated improved progression-free survival over standard chemoimmunotherapy for previously untreated mantle cell lymphoma (MCL) in patients 65 and over, researchers from The University of Texas MD Anderson Cancer Center reported today at the 2022 American Society of Clinical Oncology Annual Meeting.

3 Jun 2022

Easily Acquire Expert-Quality Images with the APEXVIEW™ APX100 All-in-One Microscope

Built with renowned Olympus optics, intuitive software, a powerful AI and a suite of smart features, the APX100 system combines the ease of use of an all-in-one microscope with publication-quality images to make life science research more efficient.

From Evident Corporation - Life Sciences 3 Jun 2022

B Cell News and Research

Autoantibody found to cause schizophrenia-like behaviors in mice

Three-drug therapy with autologous stem cell transplant improves progression-free survival for multiple myeloma patients

New nanoparticles may pave the way for development of clinical sepsis therapy

MIT researchers identify components of mucus that can inhibit fungal infections

Curia Adopts the Berkeley Lights Platform to Expand its Antibody Discovery Capabilities

Persistence of viral RNA following acute infection

Study confirms the benefits of 'bridge therapy' for some children with high-risk neuroblastoma

New trial examines the effectiveness of combination immunotherapy for platinum-resistant ovarian cancer

Trial of peptide-centered SARS-CoV-2 T-cell activator in B-cell deficient individuals

Taking everolimus post-surgery can improve outcomes in patients with high-risk renal cell carcinoma

Using DNA droplets for early disease detection

Researchers identify predictive biomarkers to fight against non-small cell lung cancer

New combination of drugs increases survival time for some patients with refractory lung cancer

Study: Nearly 43% of patients with KRAS-mutated lung cancer respond to experimental drug adagrasib

Combinations of multiple genetic factors play a role in the broad spectrum of autism

Computer vision tool effectively distinguishes rheumatoid arthritis from osteoarthritis in joint tissue

Epidemiology and the public health response of monkeypox

Steady-state DNA motion allows cells to conduct housekeeping tasks under similar nuclear environments

Ibrutinib plus chemoimmunotherapy prolonged progression-free survival in previously untreated mantle cell lymphoma patients

Easily Acquire Expert-Quality Images with the APEXVIEW™ APX100 All-in-One Microscope

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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