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New study suggests broad neutralizing antibody could provide three years of COVID protection

In a recent article published in the journal Science Translational Medicine, researchers showed that a novel, lab-engineered monoclonal antibody (mAb), adintrevimab conferred up to 50% protection against symptomatic coronavirus disease 2019 (COVID-19). Furthermore, it demonstrated this exceptional efficacy in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–naïve individuals even at titers as low as 1:30.

27 Mar 2023

Researchers receive NCI grant to advance new treatment approach for pancreatic cancer

Cosimo Commisso, Ph.D., and Susanne Heynen-Genel, Ph.D., have received a grant from the National Cancer Institute to advance a new treatment approach for pancreatic cancer.

27 Mar 2023

Epigenome reprogramming after SARS-CoV-2 infection

Researchers performed a 3D evaluation of SARS-CoV-2 infected human cells.

27 Mar 2023

Dormant cone photoreceptors in the degenerating retina may retain visual function, research suggests

New UCLA research in mice suggests that "dormant" cone photoreceptors in the degenerating retina are not dormant at all, but continue to function, producing responses to light and driving retinal activity for vision.

27 Mar 2023

Combination treatment for advanced endometrial cancer significantly reduces disease growth

In a study published in the March 27, 2023, online edition of the New England Journal of Medicine, researchers at the University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health found the combination of immunotherapy (pembrolizumab) and chemotherapy in patients with advanced or recurrent/advanced endometrial cancer resulted in a significant reduction in disease growth when compared with chemotherapy alone.

27 Mar 2023

Developers of gene therapies can utilize FDA guidance to prepare ODD or RPDD applications

Providing an overview of the submissions process and examples of U.S. Food and Drug Administration (FDA) applications for Orphan Drug Designation (ODD) and Rare Pediatric Disease Designation (RPDD), a new article can help developers of gene therapies for rare genetic diseases.

27 Mar 2023

Chronological and biological age may be important determinants of vaccine-preventable outcomes

A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 5, entitled, "Parsing chronological and biological age effects on vaccine responses."

27 Mar 2023

Myeloid cells can harbor HIV in people taking antiretroviral therapy

A subset of white blood cells, known as myeloid cells, can harbor HIV in people who have been virally suppressed for years on antiretroviral therapy, according to findings from a small study supported by the National Institutes of Health.

27 Mar 2023

Researchers discover a new role for one of the genes linked to hereditary spastic paraplegia

Researchers from the University of Seville and the Seville Institute of Biomedicine (IBiS), in collaboration with the University of Cambridge, have identified a new role for one of the genes related to hereditary spastic paraplegia.

27 Mar 2023

Breast tumors of women from different racial groups have diverse cellular, microbial and genomic features

The breast tumors of Asian, Black and white women have very different cellular, microbial and genomic features that could potentially be used to personalize care or predict disease progression, according to new research by investigators at the Johns Hopkins Kimmel Cancer Center.

27 Mar 2023

Targeting the STING pathway with a combination strategy promotes antitumor activity

Immunotherapies have greatly improved the outcomes of many patients with melanoma. But there is still a need for new approaches for the subset of patients who do not respond well to this type of therapy.

27 Mar 2023

New statement suggests next steps to interpret incidentally identified gene variants related to heart disease

Increasing use of genetic testing means people may discover they have a gene variant associated with some types of cardiovascular disease (CVD).

27 Mar 2023

Human cells help scientists to better understand squid skin cells

Squids and octopuses are masters of camouflage, blending into their environment to evade predators or surprise prey.

27 Mar 2023

Discovery enables a clear diagnosis for more patients with androgen insensitivity syndrome

Steroid hormones, to which belong sex hormones like estrogen or testosterone, are important signaling molecules and are responsible among other things for controlling female and male phenotypic sex differentiation.

27 Mar 2023

Forward genetic screening reveals important pathways for sleep regulation in C. elegans

Although the regulation of sleep—how much, when, and how sleep occurs—is mainly considered to be controlled by the brain, sleep deprivation also affects the body, and signals from the body can affect sleep.

27 Mar 2023

Understanding Mtb's nitrogen metabolism could pave the way for more effective TB treatments

Development of new drugs to effectively target the bacterium that causes tuberculosis (TB) could be one step closer following an important discovery from the University of Surrey.

27 Mar 2023

New study aims to help physically disabled people gain better access to cervical screening

A team of researchers led by Keele University - comprising psychologists, GPs, and nurses - are leading a new study funded by the National Institute for Health and Care Research to help physically disabled women and people with a cervix gain better access to cervical screening, in a bid to reduce cervical cancer.

27 Mar 2023

Light therapy may benefit heart health and longevity

Light therapy has demonstrated its usefulness in treating a variety of diseases. But can it delay the occurrence of age-related disease?

27 Mar 2023

New technology can rapidly analyze the metabolic state of lipids in cells

Professor Itaru Hamachi, Lecturer Tomonori Tamura, and Assistant Professor Masaki Tsuchiya of Kyoto University have developed a new technology called O-ClickFC (Organelle-selective click labeling with flow cytometry), which can, at a very high speed, analyze the metabolic state of lipids in cells.

27 Mar 2023

Enhancing the effectiveness of immunization against certain cancers

In addition to an antigen, many vaccines also contain substances, called adjuvants, which stimulate the immune system.

27 Mar 2023

Cell News and Research

New study suggests broad neutralizing antibody could provide three years of COVID protection

Researchers receive NCI grant to advance new treatment approach for pancreatic cancer

Epigenome reprogramming after SARS-CoV-2 infection

Dormant cone photoreceptors in the degenerating retina may retain visual function, research suggests

Combination treatment for advanced endometrial cancer significantly reduces disease growth

Developers of gene therapies can utilize FDA guidance to prepare ODD or RPDD applications

Chronological and biological age may be important determinants of vaccine-preventable outcomes

Myeloid cells can harbor HIV in people taking antiretroviral therapy

Researchers discover a new role for one of the genes linked to hereditary spastic paraplegia

Breast tumors of women from different racial groups have diverse cellular, microbial and genomic features

Targeting the STING pathway with a combination strategy promotes antitumor activity

New statement suggests next steps to interpret incidentally identified gene variants related to heart disease

Human cells help scientists to better understand squid skin cells

Discovery enables a clear diagnosis for more patients with androgen insensitivity syndrome

Forward genetic screening reveals important pathways for sleep regulation in C. elegans

Understanding Mtb's nitrogen metabolism could pave the way for more effective TB treatments

New study aims to help physically disabled people gain better access to cervical screening

Light therapy may benefit heart health and longevity

New technology can rapidly analyze the metabolic state of lipids in cells

Enhancing the effectiveness of immunization against certain cancers

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