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Compound isolated from Moroccan fungus shows promise to fight triple negative breast cancer

A compound isolated from a fungus growing on the roots of a flowering plant in Morocco shows promise as a powerful opponent of aggressive triple negative breast cancer, scientists say.

4 Mar 2021

Smoking cessation drug shows potential to treat Parkinson's disease in females

Texas A&M University College of Medicine ressearchers have recently discovered that cytisine -- a smoking cessation drug commonly used in Europe -- reduces the loss of dopamine neurons in females. These findings provide potential evidence for the use of the drug to treat Parkinson's disease or stop its progression in women.

4 Mar 2021

Digital health solution helps reduce key symptoms of chronic pain

For the first time, an app has been shown to reduce key symptoms of chronic pain. A UHN-led study evaluated the impact of Manage My Pain (MMP), a digital health solution developed by ManagingLife, on patients seen at the Iroquois Falls Family Health Team, and the Toronto Western and Toronto General Hospitals.

4 Mar 2021

Cell surface marker CD47 may allow early diagnosis of severe COVID-19

A new study reports the potential of the cell surface marker, CD47, as a biomarker for hyperinflammation, a characteristic feature of severe COVID-19.

4 Mar 2021

Intrapericardial injection provides a less invasive means of treating cardiac injury

Injecting hydrogels containing stem cell or exosome therapeutics directly into the pericardial cavity could be a less invasive, less costly, and more effective means of treating cardiac injury, according to new research from North Carolina State University and the University of North Carolina at Chapel Hill.

4 Mar 2021

Health information from trusted sources can reduce depressive symptoms in teens

Depression can be a common problem for teens and adolescents, and while many treatments exist, they don't always work for everyone. A new study found that feeling more informed about their health may help teens take better care of themselves, leading to less depressive symptoms.

4 Mar 2021

COVID-19 pandemic had major impacts on childhood cancer care, shows survey

The COVID-19 pandemic has had major impacts on childhood cancer care worldwide, according to a survey of more than 300 clinicians from 200 hospitals worldwide published in The Lancet Child & Adolescent Health journal.

3 Mar 2021

Newly identified biomarker could predict response to immune checkpoint inhibitors

A team of Roswell Park Comprehensive Cancer Center researchers has identified a new biomarker that could predict response to immune checkpoint inhibitors (ICI) shortly after patients with non-small cell lung cancer (NSCLC) initiate therapy.

3 Mar 2021

Using two different viruses to tackle tumors

An international research group led by the University of Basel has developed a promising strategy for therapeutic cancer vaccines.

3 Mar 2021

PICI awards $3 million to support early career cancer researchers

From improving immunotherapy response in childhood cancer patients, to better understanding how cancer's spread to the liver affects the body's immune system, to helping T cells stay energized to fight cancer, The Parker Institute for Cancer Immunotherapy (PICI)'s 2021 class of early career researchers award recipients are pursuing ideas that have the potential to change the face of oncology.

3 Mar 2021

New substance suppresses the growth of harmful bacteria that cause periodontitis

Targeted, efficient and with few side effects: A new method for combating periodontitis could render the use of broad-spectrum antibiotics superfluous.

3 Mar 2021

Combination of therapies may benefit patients with mitochondrial respiratory chain disorders

Researchers from the Mitochondrial Medicine Frontier Program at Children's Hospital of Philadelphia (CHOP) have demonstrated how one combination of therapies may be beneficial for patients with mitochondrial respiratory chain disorders.

3 Mar 2021

Cognitive behavioral therapy can reduce stress, improve mood in pregnant women

Perinatal depression has soared during the pandemic. But many mental health professionals are overwhelmed and can't take on new clients.

3 Mar 2021

Study suggests a new way to detect heart disease through non-invasive tool

In a new study from Shiley Eye Institute at UC San Diego Health, researchers have identified a potential new marker that shows cardiovascular disease may be present in a patient using an optical coherence tomography (OCT) scan -- a non-invasive diagnostic tool commonly used in ophthalmology and optometry clinics to create images of the retina.

3 Mar 2021

Early antibody response predicts COVID-19 outcome

To address this gap, researchers from the U.S. evaluated the timing of antibody production against SARS-CoV-2 in hospitalized patients. They used a highly sensitive multiplexed bead-based immunoassay that allows for early detection of anti-SARS-CoV-2 antibodies. The study is published on the preprint server medRxiv.

2 Mar 2021

Sequential administration of immunotherapy and targeted therapy prolongs anti-tumor responses

Advanced melanoma is one of the deadliest types of cancer, with a 5-year survival rate of only 27% for patients with distant metastases.

2 Mar 2021

Study evaluates the effectiveness of methoxyflurane versus standard care for pain management in the ED

Initial management with inhaled methoxyflurane in the emergency department did not achieve the prespecified substantial reduction in pain, but was associated with clinically significant lower pain scores compared to standard therapy.

2 Mar 2021

Researchers develop a genetic patch to prevent hereditary deafness

They can hear well up to about forty years old, but then suddenly deafness strikes people with DFNA9. The cells of the inner ear can no longer reverse the damage caused by a genetic defect in their DNA.

2 Mar 2021

New drug could prevent Alzheimer's by modulating key enzyme involved in amyloid plaque formation

Amyloid plaques are pathological hallmarks of Alzheimer's disease (AD) -- clumps of misfolded proteins that accumulate in the brain, disrupting and killing neurons and resulting in the progressive cognitive impairment that is characteristic of the widespread neurological disorder.

2 Mar 2021

Experimental therapy delays viral rebound in SHIV-infected macaques

A recent preclinical study by U.S. Military HIV Research Program (MHRP) researchers showed that an experimental therapy combining a TLR7 agonist and two broadly neutralizing antibodies delayed viral rebound in SHIV-infected macaques after antiretroviral therapy (ART) interruption.

2 Mar 2021

Therapy News and Research

Compound isolated from Moroccan fungus shows promise to fight triple negative breast cancer

Smoking cessation drug shows potential to treat Parkinson's disease in females

Digital health solution helps reduce key symptoms of chronic pain

Cell surface marker CD47 may allow early diagnosis of severe COVID-19

Intrapericardial injection provides a less invasive means of treating cardiac injury

Health information from trusted sources can reduce depressive symptoms in teens

COVID-19 pandemic had major impacts on childhood cancer care, shows survey

Newly identified biomarker could predict response to immune checkpoint inhibitors

Using two different viruses to tackle tumors

PICI awards $3 million to support early career cancer researchers

New substance suppresses the growth of harmful bacteria that cause periodontitis

Combination of therapies may benefit patients with mitochondrial respiratory chain disorders

Cognitive behavioral therapy can reduce stress, improve mood in pregnant women

Study suggests a new way to detect heart disease through non-invasive tool

Early antibody response predicts COVID-19 outcome

Sequential administration of immunotherapy and targeted therapy prolongs anti-tumor responses

Study evaluates the effectiveness of methoxyflurane versus standard care for pain management in the ED

Researchers develop a genetic patch to prevent hereditary deafness

New drug could prevent Alzheimer's by modulating key enzyme involved in amyloid plaque formation

Experimental therapy delays viral rebound in SHIV-infected macaques

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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