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Potential role of chitinase 3-like-1 in severity of COVID-19

Now, an intriguing preprint research paper on the bioRxiv server reports the identification of an enzyme called chitinase 3-like-1 (CHI3L1) that mediates this age-dependent impact of the virus and could serve as a powerful therapeutic approach in mitigating the severity of COVID-19 in this high-risk group.

7 Jan 2021

Mount Sinai launches new center for psychedelics research

The Icahn School of Medicine at Mount Sinai has launched a new center for psychedelics research.

7 Jan 2021

Study explores women's interest in long-acting injectable antiretroviral therapy

A study led by Columbia University Mailman School of Public Health researchers examines attitudes toward long-acting injectable (LAI) HIV therapies, among women with a history of injection--including medical purposes and substance use. The findings appear in the journal AIDS Patient Care and STDs.

7 Jan 2021

Study addresses how to mitigate the mental health impact of Covid-19 lockdown

The Covid-19 pandemic is impacting people's mental health. But what helps and hinders people in getting through a lockdown? A new study led by researchers at the University of Basel addressed this question using data from 78 countries across the world.

7 Jan 2021

Common gene expression changes at target tissues of four autoimmune diseases found

Autoimmune diseases are diseases of "mistaken identity", where the immune system - which is supposed to protect us against infectious diseases and neoplasias - mistakenly attacks and destroys components of our own body.

7 Jan 2021

Researchers develop new sequencing-based approach for pathogen discovery

A sequencing-based solution can be utilized to determine infection clearance and microbiota recovery. Next, the researchers will apply the technique to investigate the coronavirus disease.

7 Jan 2021

Researchers examine effective treatments for victims struggling with chronic pain and PTSD

Post-traumatic stress disorder, or PTSD, affects many people who are exposed to extreme situations, such as torture. Recent research suggests that chronic pain may make it more difficult to treat trauma

7 Jan 2021

Main bioactive compound of ginger root may protect against autoimmune disease progression

Naturopathic medicine, or herbal medicine, is all the rage, especially among young people. But how much of this is supported by science?

6 Jan 2021

RedHill Biopharma: RHB-204 receives FDA Fast Track designation for treatment of NTM disease

RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced that RHB-204 has been granted Fast Track designation by the U.S. Food and Drug Administration for its development as a potential first-line, stand-alone, oral treatment of pulmonary nontuberculous mycobacteria (NTM) disease caused by Mycobacterium avium Complex (MAC) - a rare disease for which there is no FDA-approved first-line therapy.

6 Jan 2021

Study identifies determinants that affect woman's risk of sexual dysfunction

Sexual dysfunction often accompanies the menopause transition. Yet, not all women experience it the same.

6 Jan 2021

Using a blood test to predict Alzheimer's disease risk during symptom-free stage

Using a blood test, a German-Dutch research team has predicted the risk of Alzheimer's disease in people who were clinically diagnosed as not having Alzheimer's disease but who perceived themselves as cognitively impaired (Subjective Cognitive Declined, SCD).

6 Jan 2021

Huntington’s disease mutant gene affects brain and body growth in childhood

There is growing evidence to support the hypothesis that there is a neurodevelopmental component to the late-onset neurodegeneration occurring in the brain of huntingtin gene (HTT gene) mutation carriers, and that this increased susceptibility to brain cell death begins during childhood.

6 Jan 2021

NIAID set to conduct large monoclonal SARS-CoV-2 antibody clinical trial

A large clinical trial, known as the Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV-2), is set to take place, which aims to test monoclonal antibody efficacy and safety in people who have mild or moderate COVID-19.

6 Jan 2021

Gut microbe may play a role in the development of breast cancers

A microbe found in the colon and commonly associated with the development of colitis and colon cancer also may play a role in the development of some breast cancers, according to new research from investigators with the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

6 Jan 2021

Are SARS-CoV-2 antibodies associated with disease enhancement?

As SARS-CoV-2 continues to wreak its havoc, antibodies that neutralize the virus and protect against infection have become an important focus of research. However, there is a concern as to whether these antibodies can actually enhance the disease.

6 Jan 2021

Children’s hospitals grapple with wave of mental illness

Krissy Williams, 15, had attempted suicide before, but never with pills.

6 Jan 2021

Mindfulness-based cognitive therapy may protect patients against depressive relapse

Findings from a recent study of individuals with depression suggest that Mindfulness-Based Cognitive Therapy (MBCT) can improve how patients feel about themselves in difficult situations in ways that may help protect against relapse of depressive symptoms.

6 Jan 2021

Study: Decreased activation of LEF1 gene disrupts ordinary neuronal function

Lithium is considered the gold standard for treating bipolar disorder (BD), but nearly 70 percent of people with BD don't respond to it.

5 Jan 2021

Researchers identify natural products with potential to disrupt viral spread

Researchers at Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California San Diego have broken down the genomic and life history traits of three classes of viruses that have caused endemic and global pandemics in the past and identify natural products - compounds produced in nature - with the potential to disrupt their spread.

5 Jan 2021

One-third of COVID-19 survivors manifest neurological problems

In a longitudinal study recently published on the preprint server medRxiv*, Andrea Pilotto et al. find that one-third of COVID-19 infection survivors have long-term neurological manifestations after hospitalization.

5 Jan 2021