B Cell News and Research

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New research may open a window to treating aggressive form of B-cell acute lymphoblastic leukemia

Survival has improved greatly in children with acute lymphocytic leukemia (ALL). But a certain form of ALL that occurs mostly in babies is still very lethal, with a survival rate below 50 percent: B-cell acute lymphoblastic leukemia with rearrangements of the mixed lineage leukemia gene, or MLL B-ALL.

1 Jun 2022

Surprising outcomes trigger release of noradrenaline in the brain, MIT study finds

When your brain needs you to pay attention to something important, one way it can do that is to send out a burst of noradrenaline, according to a new MIT study.

1 Jun 2022

Scientists unlock the cellular secrets of aging process

New research has uncovered how genetic changes that accumulate slowly in blood stem cells throughout life are likely to be responsible for the dramatic change in blood production after the age of 70.

1 Jun 2022

Membrane lipid stops stress reactions and inhibits cell death

Programmed cell death is an important tool that an organism uses to keep itself healthy. When a cell does not function as it should, various stress reactions are activated. The goal of these reactions is to restore the original cell function.

1 Jun 2022

Genetically modified herpes virus can be used in the fight against cancer

Viruses can make animals and humans sick - or healthy: Researchers at the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB have succeeded in genetically modifying the herpes simplex virus type 1, which triggers painful cold sores, in such a way that it can be used in the fight against cancer in the future.

1 Jun 2022

Neuroscientists study the formation of fear memories in the brain's emotional hub

Experiencing a frightening event is likely something you'll never forget. But why does it stay with you when other kinds of occurrences become increasingly difficult to recall with the passage of time?

1 Jun 2022

Highly sensitive blood test could give doctors a new tool to quickly identify and treat tuberculosis

Researchers at Tulane University School of Medicine have developed a new highly sensitive blood test for tuberculosis (TB) that screens for DNA fragments of the Mycobacterium tuberculosis bacteria that causes the deadly disease.

1 Jun 2022

Study finds a link between aging and cancer metastases

Spreading cancer cells that escape a primary tumor site can seed in tissues distant from the tumor, but may take several years or decades to grow into full metastatic cancers.

1 Jun 2022

Researchers identify chemical compound that may short-circuit brain cell death in Parkinson's disease

In studies in mice, Johns Hopkins Medicine researchers say they have identified a chemical compound that stops the final events in the pathway linked to the death of brain cells in Parkinson's disease.

1 Jun 2022

New findings reveal potential mechanisms for cellular defects in human laminopathies

A Northwestern Medicine study has uncovered distinct roles for major nuclear lamin isoforms in maintaining intracellular interactions and cellular mechanics, according to findings published in the Proceedings of the National Academy of Sciences.

1 Jun 2022

Combination bNAb therapy may offer a future alternative to daily ART for people living with HIV

Individuals with HIV who began taking antiretroviral therapy (ART) in the early stages of infection achieved a lengthy period of HIV suppression without ART after receiving two broadly neutralizing anti-HIV antibodies (bNAbs), according to a small study published today in the journal Nature.

1 Jun 2022

Study shows the SARS-CoV-2 accessory protein ORF7a inhibits HLA-I surface expression levels in human cells

Researchers identified a single viral gene product, the accessory factor ORF7a, facilitating SARS-CoV-2 immune evasion by downregulating the surface expression of MHC class I molecules.

1 Jun 2022

seqWell and Element Biosciences partner to demonstrate sequencing performance of multiplexed plexWell technology with the AVITI System

seqWell today announced a partnership with Element Biosciences Inc., developer of the Element AVITI™ System.

From Element Biosciences 1 Jun 2022

UCI-led study identifies sex-specific circuits of muscle signaling to other tissues

A new University of California, Irvine-led study identifies sex-specific circuits of muscle signaling to other tissues and that the organs and processes muscle impacts are markedly different between males and females.

31 May 2022

Researchers identify molecular characteristics linked to increased likelihood of post-vaccination fatigue

Despite their strong effectiveness against SARS-CoV-2, mRNA-based COVID-19 vaccines are associated with adverse post-vaccination effects, such as fatigue; how can this be avoided? In a new study publishing May 31st in the open-access journal PLOS Biology, Ayesa Syenina of the Duke–NUS Medical School in Singapore and colleagues report that a new analysis of blood samples from people vaccinated for COVID-19 has identified distinct molecular characteristics linked to an increased likelihood of post-vaccination fatigue.

31 May 2022

Aging does not influence liver renewal, research shows

The liver has a unique ability to regenerate after damage. However, it was unknown whether this ability decreases as we age.

31 May 2022

Exposure to traffic-related air pollutants linked with pregnancy complications

A new study in mice by UCLA scientists reveals how exposure to traffic-related air pollutants causes cellular changes in the placenta that can lead to pregnancy complications and affect the health of both mother and offspring.

31 May 2022

UCLA researchers identify a method to make tumors susceptible to immune attack

One powerful way cancer cells defend against tumor-killing immune cells is to load up their cell surface with a protein known as PD-L1. Now a team of UCLA Jonsson Comprehensive Cancer Center researchers led by Roger S. Lo, MD, PhD, has identified a method to degrade tumor cell-surface PD-L1, thereby making tumors susceptible to immune attack.

31 May 2022

Study highlights the positive effects of Humanin G in reducing inflammation in AMD

A new research paper was published in Aging (Aging-US) on the cover of Volume 14, Issue 10, entitled, "Effect of Humanin G (HNG) on inflammation in age-related macular degeneration (AMD)."

31 May 2022

New class of antibiotics found to be highly effective against drug-resistant tuberculosis

Infection by Mycobacterium tuberculosis kills 1.5 million people worldwide every year. Antibiotics to treat TB exist, but in recent years, multi-drug resistant (MDR), extensively drug-resistant (XDR) and totally drug-resistant (TDR) strains of the bacterium have developed.

31 May 2022

B Cell News and Research

New research may open a window to treating aggressive form of B-cell acute lymphoblastic leukemia

Surprising outcomes trigger release of noradrenaline in the brain, MIT study finds

Scientists unlock the cellular secrets of aging process

Membrane lipid stops stress reactions and inhibits cell death

Genetically modified herpes virus can be used in the fight against cancer

Neuroscientists study the formation of fear memories in the brain's emotional hub

Highly sensitive blood test could give doctors a new tool to quickly identify and treat tuberculosis

Study finds a link between aging and cancer metastases

Researchers identify chemical compound that may short-circuit brain cell death in Parkinson's disease

New findings reveal potential mechanisms for cellular defects in human laminopathies

Combination bNAb therapy may offer a future alternative to daily ART for people living with HIV

Study shows the SARS-CoV-2 accessory protein ORF7a inhibits HLA-I surface expression levels in human cells

seqWell and Element Biosciences partner to demonstrate sequencing performance of multiplexed plexWell technology with the AVITI System

UCI-led study identifies sex-specific circuits of muscle signaling to other tissues

Researchers identify molecular characteristics linked to increased likelihood of post-vaccination fatigue

Aging does not influence liver renewal, research shows

Exposure to traffic-related air pollutants linked with pregnancy complications

UCLA researchers identify a method to make tumors susceptible to immune attack

Study highlights the positive effects of Humanin G in reducing inflammation in AMD

New class of antibiotics found to be highly effective against drug-resistant tuberculosis

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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