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VGX International, Inovio partner to co-develop SynCon vaccines for hepatitis B and C infections

Inovio Pharmaceuticals, Inc., a leader in the development of synthetic vaccines against cancers and infectious diseases, announced today that it has entered into a product development collaboration agreement with its affiliate, VGX International Inc., to co-develop Inovio's SynCon therapeutic vaccines for hepatitis B and C infections.

10 Oct 2011

Researchers examine effects of antirejection drugs in kidney transplant patients

Modern medicine's ability to save lives through organ transplantation has been revolutionized by the development of drugs that prevent the human body from rejecting the transplanted organ.

10 Oct 2011

New siRNA treatment reduces damaging inflammation in animals models of several disorders

Massachusetts General Hospital (MGH) researchers - along with collaborators from Massachusetts Institute of Technology (MIT) and Alnylam Pharmaceuticals - have found a way to block, in an animal model, the damaging inflammation that contributes to many disease conditions.

10 Oct 2011

First successful quantification of membrane lipids in a living cell

Could controlling cell-membrane fat play a key role in turning off disease? Researchers at the University of Illinois at Chicago think so, and a biosensor they've created that measures membrane lipid levels may open up new pathways to disease treatment.

10 Oct 2011

Advocates prepare for battle on PSA testing; insurers review options

A day after a government panel said that healthy men should no longer get screened for prostate cancer, some doctors' groups and cancer patients' advocates began a campaign to convince the nation that the advice was misguided. Their hope is to copy the success of women's groups that successfully persuaded much of the country two years ago that it was a mistake for the same panel, the United States Preventive Services Task Force, to recommend against routine mammograms for women in their 40s.

10 Oct 2011

Researchers identify cellular pathway to potentially block disease-inducing inflammation

Researchers have discovered a cellular pathway that promotes inflammation in diseases like asthma, rheumatoid arthritis, psoriasis, inflammatory bowel disease, and multiple sclerosis. Understanding the details of this pathway may provide opportunities for tailored treatments of inflammatory and autoimmune diseases.

10 Oct 2011

Preventive task force panel will urge men to skip prostate screening, reports say

The U.S. Preventive Services Task Force is scheduled to issue this recommendation on Tuesday, but advance press reports indicate the expert panel will urge the federal government to change its current position to recommend that men under age 75 forgo this widely used test.

7 Oct 2011

Nutrition tips for long-distance runners

With marathon trainees about to take to the streets of Chicago this Sunday, Loyola University Health System registered dietitian Brooke Schantz offers the top 10 nutrition tips runners can follow to help them cross the finish line.

7 Oct 2011

USPTO awards HistoRx two patents for methods of standardization of digital microscopy instruments

HistoRx, the leader in quantitative immunohistochemistry, advances its proprietary position in digital pathology through the recent issuance of US patents covering key features necessary for achievement of reproducible, standardized image analysis results.

7 Oct 2011

Calcium supplementation does not benefit pregnant women, except for hypertension

Most physicians instruct pregnant women to increase their calcium intake, but a new evidence review of potential benefits of calcium supplementation for mom and baby found none, except for the prevention of pregnancy-related hypertension.

7 Oct 2011

Scientists discover two HIV variants in cerebrospinal fluid of HAD patients

When the virus that causes AIDS infects the central nervous system, it can lead to the development of a severe neurological disease called HIV- associated dementia.

7 Oct 2011

NCKU research team discovers potential target to treat osteoporosis

A National Cheng Kung University (NCKU) research team has discovered that a protein called interleukin (IL)-20 is a key to treating osteoporosis, a disease that lowers a person's bone density.

7 Oct 2011

Hysterectomy increases brain iron levels in both men and women

The human body has a love-hate relationship with iron. Just the right amount is needed for proper cell function, yet too much is associated with brain diseases like Alzheimer's and Parkinson's.

7 Oct 2011

Scientists discover new metabolic pathway which makes gliomas more aggressive

A research alliance of Heidelberg University Hospital and the German Cancer Research Center, jointly with colleagues of the Helmholtz Center for Environmental Research in Leipzig, have discovered a new metabolic pathway which makes malignant brain tumors (gliomas) more aggressive and weakens patients' immune systems.

7 Oct 2011

JCO publishes data from Celgene's ABRAXANE Phase II combination trial on pancreatic cancer

Celgene International Sàrl today announced that results from a clinical study of ABRAXANE in combination with gemcitabine in 67 patients with previously untreated advanced pancreatic cancer were published in an online article by the Journal of Clinical Oncology ahead of print.

7 Oct 2011

Herceptin chemo combination could mean longer survival and lower side effects in breast cancer patients: Study

A new study released this Wednesday revealed that breast cancer that is highly aggressive but caught early could be best treated with a combination of Herceptin and chemotherapy.

6 Oct 2011

X-BODY, TRL enter collaboration to identify therapeutic target epitopes

X-BODY, Inc., a developer of monoclonal antibody therapeutics, today announced a partnership with Tanabe Research Laboratories U.S.A., Inc. (TRL). The companies will collaborate to identify therapeutic target epitopes and develop monospecific and/or bispecific antibodies to the identified therapeutic targets.

4 Oct 2011

Muscle cannot be functionally reactivated if you're too late

When a motor nerve is severely damaged, people rarely recover full muscle strength and function. Neuroscientists from Children's Hospital Boston, combining patient data with observations in a mouse model, now show why. It's not that motor nerve fibers don't regrow – they can – but they don't grow fast enough. By the time they get to the muscle fibers, they can no longer communicate with them.

4 Oct 2011

Virus DNA uncoated with aid of host cell

They have been around since the dawn of time and are a model of evolutionary success: viruses. Viruses are extremely adaptable but they have a problem: They cannot reproduce, so they smuggle their genes into suitable host cells. In the case of some viruses, the viral DNA has to enter the cell nucleus to reproduce. This has been known for almost 50 years.

4 Oct 2011

Lipomannan on TB bacterium's outer cell surface can block TNF production

The bacterium that causes tuberculosis has a unique molecule on its outer cell surface that blocks a key part of the body's defense. New research suggests this represents a novel mechanism in the microbe's evolving efforts to remain hidden from the human immune system.

4 Oct 2011

G Protein News and Research

VGX International, Inovio partner to co-develop SynCon vaccines for hepatitis B and C infections

Researchers examine effects of antirejection drugs in kidney transplant patients

New siRNA treatment reduces damaging inflammation in animals models of several disorders

First successful quantification of membrane lipids in a living cell

Advocates prepare for battle on PSA testing; insurers review options

Researchers identify cellular pathway to potentially block disease-inducing inflammation

Preventive task force panel will urge men to skip prostate screening, reports say

Nutrition tips for long-distance runners

USPTO awards HistoRx two patents for methods of standardization of digital microscopy instruments

Calcium supplementation does not benefit pregnant women, except for hypertension

Scientists discover two HIV variants in cerebrospinal fluid of HAD patients

NCKU research team discovers potential target to treat osteoporosis

Hysterectomy increases brain iron levels in both men and women

Scientists discover new metabolic pathway which makes gliomas more aggressive

JCO publishes data from Celgene's ABRAXANE Phase II combination trial on pancreatic cancer

Herceptin chemo combination could mean longer survival and lower side effects in breast cancer patients: Study

X-BODY, TRL enter collaboration to identify therapeutic target epitopes

Muscle cannot be functionally reactivated if you're too late

Virus DNA uncoated with aid of host cell

Lipomannan on TB bacterium's outer cell surface can block TNF production

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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