Genetic News and Research

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SARS-CoV-2 antibodies and COVID symptoms can last at least 3 months

Recent research published as a preprint on the medRxiv preprint server, Elizabeth T. Cirulli et al., studies the self-reported short and long-term symptoms in a large general adult population cohort.

13 Oct 2020

Study reveals why immobilization after injury helps in healing

By far, the most common injuries seen in emergency rooms in the United States are those affecting extremities. Immobilization is the most common treatment, and yet, until recently, it was unknown exactly why this technique worked to advance healing.

12 Oct 2020

Study provides a new depth of resolution to understand single gene disorders

Traditionally, geneticists divide disorders into "simple," where a single gene mutation causes disease, or complex, where mutations in many genes contribute modest amounts. A new study suggests that the truth is somewhere in between.

12 Oct 2020

Study elucidates the role of ERβ in growth of skeletal muscle in female mice

Researchers at Kumamoto University, Japan generated mice lacking the estrogen receptor beta (ERβ) gene, both fiber-specific and muscle stem cell-specific, which resulted in abnormalities in the growth and regeneration of skeletal muscle in female mice.

12 Oct 2020

Gene variations that regulate dopamine levels in the brain may influence mobility of elderly, frail adults

Variations in a gene that regulates dopamine levels in the brain may influence the mobility of elderly and frail adults, according to new research from the University of Pittsburgh Graduate School of Public Health.

12 Oct 2020

Study highlights ongoing disparity in inflammatory breast cancer

Women with inflammatory breast cancer - a rare, highly aggressive form of the disease - are living about twice as long after diagnosis than their counterparts in the mid-to-late 1970s, according to a new University of Michigan Rogel Cancer Center study.

12 Oct 2020

Researchers examine the cooperative effects of genes in suppressing neuroendocrine tumors in mice

Volume 11, Issue 28 of Oncotarget features "Genetic analysis of the cooperative tumorigenic effects of targeted deletions of tumor suppressors Rb1, Trp53, Men1, and Pten in neuroendocrine tumors in mice" by Xu et, al. which reported that the authors examined whether the TSGs Rb1, Trp53, Pten, and Men1 have cooperative effects in suppressing neuroendocrine tumors in mice.

12 Oct 2020

New study may lead to more effective, personalized cancer immunotherapies

Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies.

12 Oct 2020

CWRU and UH secure $4 million to establish research center focused on lung cancer in East Africa

Researchers with the Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center have secured $4 million in funding from the National Institutes of Health (NIH)/National Cancer Institute to establish an HIV-associated Malignancy Research Center (HAMRC) focused on lung cancer in East Africa.

9 Oct 2020

New initiative identifies key parameters underlying effective anti-tumor immunity

Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies.

9 Oct 2020

NIH provides $9.3 million grant to create new Center for Precision Animal Modeling at UAB

A new Center for Precision Animal Modeling, or C-PAM, has been created at the University of Alabama at Birmingham, supported by a five-year, $9.3 million grant from the National Institutes of Health's Office of Research Infrastructure Programs.

9 Oct 2020

Researchers participate in nationwide study to discover new forms of diabetes

Indiana University School of Medicine researchers are participating in the Rare and Atypical Diabetes Network (RADIANT), a nationwide study funded by the National Institutes of Health. The study seeks to discover new forms of diabetes, identify their causes, and understand how they differ from more common types of diabetes.

9 Oct 2020

Findings could bring hope for novel therapeutic strategies against malaria

The Plasmodium parasite, which transmits malaria to humans through infected mosquitos, triggers changes in human genes that alter the body's adaptive immune response to malarial infections, according to a team of researchers at NYU Abu Dhabi (NYUAD).

9 Oct 2020

UroCAD assay is better than urine cytology in detecting bladder cancer

Analysis of DNA copy number variants (CNVs) in the cells exfoliated in urine showed better sensitivity and similar specificity in detecting urothelial carcinoma compared with urine cytology.

9 Oct 2020

New quality control system in protein production assembly can shed light on neurogenerative disease

Recent work led by Carnegie's Kamena Kostova revealed a new quality control system in the protein production assembly line with possible implications for understanding neurogenerative disease.

9 Oct 2020

Neurobiologists decode central mechanism of degenerative processes in brains of mouse models

Heidelberg neurobiologists decode central mechanism of degenerative processes in the brains of mouse models and develop new principle for therapeutic agents

9 Oct 2020

Study reveals how ovaries maintain a female's fertility

Recently published work from Carnegie's Allan Spradling and Wanbao Niu revealed in unprecedented detail the genetic instructions immature egg cells go through step by step as they mature into functionality.

9 Oct 2020

Transplantation of pig hearts may solve chronic shortage of donor organs

The goal of harvesting hearts from pigs to solve the chronic shortage of these donor organs appears to be in reach, according to a new scientific review by researchers at Massachusetts General Hospital (MGH).

9 Oct 2020

New model can simulate and analyze large number of viral infections

It is only 120 millionths of a millimetre in size but can bring entire countries to a standstill: the Corona virus. Even if it were to disappear one day, viral infections will still be among the most frequent and difficult-to-treat diseases in humans.

9 Oct 2020

Scientists recreate initial steps of HIV infection in a test tube

Accomplishing a feat that had been a pipe dream for decades, scientists have recreated in a test tube the first steps of infection by HIV (human immunodeficiency virus), the virus that causes AIDS (acquired immunodeficiency syndrome).

9 Oct 2020