Immune System News and Research

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LaVision BioTec reports on use of light sheet and 2-photon microscopy for brain injury research

LaVision BioTec, developers of advanced microscopy solutions for the life sciences, report on the work of Ali Ertürk, a Group Leader at the Institute for Stroke and Dementia Research (part of the Klinikum der Universität München) at the Ludwig Maximilians University in Munich, Germany.

12 May 2016

Brazilian strain of Zika virus can cause severe birth defects

Researchers at University of California San Diego School of Medicine, with colleagues in Brazil and Senegal, have described the first "direct experimental proof" that the Brazilian strain of Zika virus can actually cause severe birth defects. The findings are published in the May 11 online issue of Nature.

12 May 2016

Human gut model HuMiX represents actual conditions, processes that occur within intestines

One of the most complex human organs is the digestive tract: Here, the body comes into contact with all manner of diet-derived compounds and with countless bacteria.

11 May 2016

Patient-specific immunotherapeutic vaccines may improve overall survival of melanoma patients

Two patients with melanoma that had spread to the liver survived for at least 8.5 and 12 years after resection of the hepatic tumor and treatment with patient-specific immunotherapeutic vaccines.

11 May 2016

Griffith researchers closer to identifying cause of Chronic Fatigue Syndrome

New findings regarding the pathology of Chronic Fatigue Syndrome (CFS) are bringing Griffith University researchers closer to identifying the cause of this disabling illness.

11 May 2016

Titanium dioxide nanoparticles can have low-level effects on oxidative stress genes

A nanoparticle commonly used in food, cosmetics, sunscreen and other products can have subtle effects on the activity of genes expressing enzymes that address oxidative stress inside two types of cells.

11 May 2016

University of Glasgow-led study could lead to improved treatments for lymphoma, other cancers

A study by scientists at the University of Glasgow, which reveals the critical role a common cancer-associated gene plays in lymphoma development, could lead to improved treatments for a range of cancers.

11 May 2016

Simultaneous DNA, RNA and protein analysis to enhance cancer immunology studies: an interview with Dr Joseph Beechem

Cancer immunology is all about how your immune cells are going to fight and kill your tumor cells. If you look at the pure genetic code of a T-cell that's going to kill your tumor compared to the same cell that has been “put-to-sleep” (by the tumor), the pure genetic DNA content of those two cells are identical.

From NanoString Technologies 11 May 2016

Celiac disease more common among Americans with Punjabi ancestry, study shows

About 1.8 million Americans have celiac disease, an immune-based condition brought on by the consumption of gluten in genetically susceptible patients. Among patients diagnosed with celiac disease by small intestinal biopsy in the U.S., those from the Punjab region of India have the highest rates of disease, according to new research published in Clinical Gastroenterology and Hepatology,1 the official clinical practice journal of the American Gastroenterological Association.

10 May 2016

lncRNA in placenta may help protect unborn baby from invading pathogens

The human placenta is an organ unlike any other. During the course of nine months it is formed by the embryo, sustains life and then is shed.

10 May 2016

Pathogen-selective approach to antibiotic development less disruptive to gut microbiome

St. Jude Children's Research Hospital scientists report the first evidence that a pathogen-specific antibiotic was less disruptive to the gut microbiome than broad-spectrum antibiotics.

10 May 2016

Study links lower concentration of heat-shock proteins to recurrence of thymic tumors

In most cases, tumors of the thymus gland are removed by surgical resection. However, they recur after a few years in up to one third of patients. A research team headed up by thoracic surgeon Bernhard Moser of the Thoracic Surgery Department at MedUni Vienna has successfully demonstrated that these tumors form heat-shock proteins. The lower the concentration of these proteins, the more quickly tumors recur. The study has been published in the leading journal Scientific Reports.

10 May 2016

Caltech researchers discover new potential cause for Crohn's disease

The community of beneficial bacteria that live in our intestines, known as the gut microbiome, are important for the development and function of the immune system. There has been growing evidence that certain probiotics--therapies that introduce beneficial bacteria into the gut--may help alleviate some of the symptoms of intestinal disorders such as Crohn's disease.

10 May 2016

Research shows spleen MZ B cells produce signaling proteins involved in inflammatory responses

The inability to adequately respond to infection can cause a whole-body state of inflammation known as sepsis. This can eventually lead to systemic inflammatory response syndrome (SIRS), and even death.

9 May 2016

Study hints at new therapeutic approach to mitigate effects of prenatal Zika virus infection

The U.S. Centers for Disease Control and Prevention recently concluded that Zika virus infection in pregnant women can stunt neonatal brain development, leading to babies born with abnormally small heads, a condition known as microcephaly. Now, for the first time, researchers at University of California San Diego School of Medicine have determined one way Zika infection can damage developing brain cells.

9 May 2016

Researchers find way to selectively deliver drugs to placenta without harming fetus

Nearly 10 percent of babies born in the United States are born premature, according to the March of Dimes. The underlying cause of many complications during pregnancy is often a poorly functioning placenta, the organ that nourishes and maintains the fetus.

9 May 2016

New antibody-based therapy may provide better strategy for long-term control of HIV

The development of antiretroviral therapy, a combination of drugs that slows the replication of HIV in the body, has transformed the treatment of this infection. What was once a certain death sentence is now a chronic condition that people can live with for decades.

9 May 2016

Study provides vital information regarding four diagnostic PD-L1 assays

A pre-competitive consortia of pharmaceutical companies, diagnostic companies, and academic associations, including the International Association for the Study of Lung Cancer, announced phase I results of the "BLUEPRINT PD-L1 IHC ASSAY COMPARISON PROJECT" at the Annual Meeting of the American Association for Cancer Research on April 19.

6 May 2016

Genetic variations that prevent beneficial gut bacteria from working may lead to Crohn's disease

A major type of inflammatory bowel disease (IBD) may be caused in part by genetic variants that prevent beneficial bacteria in the gut from doing their job, according to a new study published today in the journal Science.

6 May 2016

T cell gives precise mechanical tugs to detect friends and foes

T cells, the security guards of the immune system, use a kind of mechanical "handshake" to test whether a cell they encounter is a friend or foe, a new study finds.

6 May 2016

Immune System News and Research

LaVision BioTec reports on use of light sheet and 2-photon microscopy for brain injury research

Brazilian strain of Zika virus can cause severe birth defects

Human gut model HuMiX represents actual conditions, processes that occur within intestines

Patient-specific immunotherapeutic vaccines may improve overall survival of melanoma patients

Griffith researchers closer to identifying cause of Chronic Fatigue Syndrome

Titanium dioxide nanoparticles can have low-level effects on oxidative stress genes

University of Glasgow-led study could lead to improved treatments for lymphoma, other cancers

Simultaneous DNA, RNA and protein analysis to enhance cancer immunology studies: an interview with Dr Joseph Beechem

Celiac disease more common among Americans with Punjabi ancestry, study shows

lncRNA in placenta may help protect unborn baby from invading pathogens

Pathogen-selective approach to antibiotic development less disruptive to gut microbiome

Study links lower concentration of heat-shock proteins to recurrence of thymic tumors

Caltech researchers discover new potential cause for Crohn's disease

Research shows spleen MZ B cells produce signaling proteins involved in inflammatory responses

Study hints at new therapeutic approach to mitigate effects of prenatal Zika virus infection

Researchers find way to selectively deliver drugs to placenta without harming fetus

New antibody-based therapy may provide better strategy for long-term control of HIV

Study provides vital information regarding four diagnostic PD-L1 assays

Genetic variations that prevent beneficial gut bacteria from working may lead to Crohn's disease

T cell gives precise mechanical tugs to detect friends and foes

Understanding the DNA Damage Response in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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