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Researchers identify 'programmed cell death' pathway in parasitic worms

Researchers from the Walter and Eliza Hall Institute have for the first time identified a 'programmed cell death' pathway in parasitic worms that could one day lead to new treatments for one of the world's most serious and prevalent diseases.

29 Sep 2011

Researchers discover kibra protein controls sculpting of brain circuitry

Researchers working with adult mice have discovered that learning and memory were profoundly affected when they altered the amounts of a certain protein in specific parts of the mammals' brains.

29 Sep 2011

Researchers use patient's own stem cells to correct genetic alteration that causes SCD

Using a patient's own stem cells, researchers at Johns Hopkins have corrected the genetic alteration that causes sickle cell disease (SCD), a painful, disabling inherited blood disorder that affects mostly African-Americans. The corrected stem cells were coaxed into immature red blood cells in a test tube that then turned on a normal version of the gene.

29 Sep 2011

FOX06 protein contributes to liver overproduction of glucose in diabetes

Researchers at the John G. Rangos Sr. Research Center at Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine have identified a powerful molecular pathway that regulates the liver's management of insulin and new glucose production, which could lead to new therapies for diabetes.

29 Sep 2011

Older women destined to develop AD have high blood levels of pregnancy protein

In an advance toward a much-needed early diagnostic test for Alzheimer's disease (AD), scientists have discovered that older women destined to develop AD have high blood levels of a protein linked to pregnancy years before showing symptoms.

29 Sep 2011

Enrollment complete in Rexahn's Archexin Phase II trial for metastatic pancreatic cancer

Rexahn Pharmaceuticals, Inc., a clinical stage pharmaceutical company commercializing potential best in class oncology and CNS therapeutics, today announced that it has completed enrollment for its Phase II clinical trial of Archexin in metastatic pancreatic cancer.

29 Sep 2011

Phase I clinical trials reveal MVA-B preventive vaccine's immune efficiency against HIV

Phase I clinical trials developed by Spanish Superior Scientific Research Council (CSIC) together with Gregorio Mara--n Hospital in Madrid and Cl-nic Hospital in Barcelona, reveals MVA-B preventive vaccine's immune efficiency against Human's immunodeficiency virus (HIV).

28 Sep 2011

Yale researchers use AB SCIEX's QTRAP technology to synthesize phosphoproteins

AB SCIEX, a global leader in life science analytical technologies, today announced that Yale University researchers used QTRAP technology to prove the validity of a new approach to synthesize phosphoproteins.

28 Sep 2011

Peru hopes to continue fight against child malnutrition under new government

Despite a seven percent annual growth rate over the past five years and a prediction from former President Alan Garcia that Peru will meet the millennium development goals (MDGs), "chronic infant malnutrition has been difficult to stamp out, particularly in rural areas," the Guardian's "Poverty Matters Blog" reports.

28 Sep 2011

Applied Biomics adds iTRAQ service to its proteomics line

Applied Biomics, Inc., a leading Proteomics service provider, is pleased to announce the addition of iTRAQ service (Isobaric Tags for Relative and Absolute Quantitation) to its proteomics line.

28 Sep 2011

Researchers validate two parasite enzymes as potential anti-malarial drug targets

Researchers at the Perelman School of Medicine at the University of Pennsylvania, Monash University, and Virginia Tech have used a set of novel inhibitors to analyze how the malaria parasite, Plasmodium falciparum, uses enzymes to chew up human hemoglobin from host red blood cells as a food source.

28 Sep 2011

Scientists identify proteasome phosphatase that appears to regulate removal of damaged proteins

A study by scientists at the University of California, San Diego and UC Irvine has identified an enzyme called a proteasome phosphatase that appears to regulate removal of damaged proteins from a cell. The understanding of how this process works could have important implications for numerous diseases, including cancer and Parkinson's disease.

28 Sep 2011

CCG announces new version of protein structure database and visualization system

Chemical Computing Group (CCG) today announces a new version of its structure database and visualization system, PSILO, featuring new analytical tools and enhanced search capabilities.

27 Sep 2011

Lead compound activates infection-fighting REDD1 protein and kills flu strain

A compound tested by UT Southwestern Medical Center investigators destroys several viruses, including the deadly Spanish flu that killed an estimated 30 million people in the worldwide pandemic of 1918.

27 Sep 2011

Scientists uncover how methylation changes can influence blood stem cell's fate

Scientists at Cold Spring Harbor Laboratory (CSHL) and the University of Southern California (USC) have uncovered intriguing new evidence helping to explain one of the ways in which a stem cell's fate can be determined.

27 Sep 2011

Weill Cornell receives NIH's T-R01 Award for spina bifida research

The National Institutes of Health (NIH) has awarded a five-year, $5.5 million Transformative Research Project (T-R01) Award to fund research into risk factors for spina bifida and related congenital defects in which an area of the affected baby's spine or brain is not fully enclosed.

27 Sep 2011

Prenatal exercise improves brain plasticity and prevents Alzheimer's in offspring

If you are pregnant, here's another reason to work out: you will reduce the chances of your new baby developing neurodegenerative diseases, such as Alzheimer's, later in life.

27 Sep 2011

Synta announces results of ganetespib, docetaxel Phase 1 combination study on solid tumors

Synta Pharmaceuticals Corp. announced that results of a Phase 1 study of ganetespib in combination with docetaxel in solid tumors were presented at the Annual Meeting of the European Society of Medical Oncology in Stockholm, Sweden.

27 Sep 2011

MSU creates new malaria vaccine with immune-stimulating gene

Continuing a global effort to prevent malaria infections, Michigan State University researchers have created a new malaria vaccine - one that combines the use of a disabled cold virus with an immune system-stimulating gene - that appears to increase the immune response against the parasite that causes the deadly disease.

27 Sep 2011

Communication breakdown between nerves and muscles in SMA mouse model

Researchers at the University of Missouri have identified a communication breakdown between nerves and muscles in mice that may provide new insight into the debilitating and fatal human disease known as spinal muscular atrophy.

27 Sep 2011

G Protein News and Research

Researchers identify 'programmed cell death' pathway in parasitic worms

Researchers discover kibra protein controls sculpting of brain circuitry

Researchers use patient's own stem cells to correct genetic alteration that causes SCD

FOX06 protein contributes to liver overproduction of glucose in diabetes

Older women destined to develop AD have high blood levels of pregnancy protein

Enrollment complete in Rexahn's Archexin Phase II trial for metastatic pancreatic cancer

Phase I clinical trials reveal MVA-B preventive vaccine's immune efficiency against HIV

Yale researchers use AB SCIEX's QTRAP technology to synthesize phosphoproteins

Peru hopes to continue fight against child malnutrition under new government

Applied Biomics adds iTRAQ service to its proteomics line

Researchers validate two parasite enzymes as potential anti-malarial drug targets

Scientists identify proteasome phosphatase that appears to regulate removal of damaged proteins

CCG announces new version of protein structure database and visualization system

Lead compound activates infection-fighting REDD1 protein and kills flu strain

Scientists uncover how methylation changes can influence blood stem cell's fate

Weill Cornell receives NIH's T-R01 Award for spina bifida research

Prenatal exercise improves brain plasticity and prevents Alzheimer's in offspring

Synta announces results of ganetespib, docetaxel Phase 1 combination study on solid tumors

MSU creates new malaria vaccine with immune-stimulating gene

Communication breakdown between nerves and muscles in SMA mouse model

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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