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NIH awards $13.8 million to conduct studies on pre-dementia and Alzheimer's disease

Joe Verghese, M.B.B.S., M.S., , an international leader in aging and cognition research at Albert Einstein College of Medicine and Montefiore Health System, has received two grants from the National Institutes of Health totaling $13.8 million to conduct studies on pre-dementia and Alzheimer's disease.

5 Oct 2020

Midges and mosquitoes unlikely to spread SARS-CoV-2

A recent study published on the preprint server bioRxiv* in September 2020 looked to see if biting insects pose a risk for transmission of SARS-CoV-2 to humans or animals following a SARS-CoV-2 infected blood meal.

5 Oct 2020

Supporting Coronavirus Research with Liquid Chromatography

The RNA in viruses such as SARS-CoV-2 are an ideal research target. RNA purification with liquid chromatography is essential in the fight against SARS-CoV-2.

From KNAUER Wissenschaftliche Geräte GmbH 5 Oct 2020

Higher prevalence of SARS-CoV-2 with D614G mutation in Washington State

The study findings also indicate that the 614G viral variant is associated with higher viral load, but not with disease severity. The study is currently available on the medRxiv preprint server.

4 Oct 2020

A comprehensive clinical and genetic model for predicting severe COVID-19 risk

While determining the risk of severe COVID-19, age, and gender are usually the only considerations. A recent preprint paper published in medRxiv, discusses how researchers from Genetic Technologies Limited, Australia, used the UK Biobank data to develop a comprehensive model that can predict severe COVID-19 risk by incorporating comorbidity risk factors, demographic information, and a set of genetic markers.

4 Oct 2020

Rapid detection of SARS-CoV-2 with portable CRISPR-based mobile phone diagnostic test

A large group of researchers from the United States reported developing an amplification-free CRISPR-based mobile phone assay for direct detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from nasal swabs. Their state-of-the-art paper is currently available on the medRxiv* preprint server.

4 Oct 2020

Identifying cardiopulmonary processes involved in severe COVID-19

Researchers in the United States have identified cardiopulmonary processes that may partly explain why some individuals with coronavirus disease 2019 (COVID-19) develop respiratory failure.

4 Oct 2020

Modeling viral clades improves prediction of COVID-19 growth rates

A new study conducted by researchers at the University of Connecticut has revealed a correlation between the prevalence of particular clades of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the growth rate of the associated illness coronavirus disease 2019 (COVID-19).

4 Oct 2020

Shedding light on origin, transmission, spread of COVID-19 in Norfolk

Researchers in the UK have conducted a large-scale whole-genome sequencing study of clinical samples positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the Norfolk area to shed light on the origins, genetic variation, transmission, and spread of the virus in the region.

4 Oct 2020

New, rare genetic form of dementia discovered

A new, rare genetic form of dementia has been discovered by a team of Penn Medicine researchers. This discovery also sheds light on a new pathway that leads to protein build up in the brain -- which causes this newly discovered disease, as well as related neurodegenerative diseases like Alzheimer's Disease -- that could be targeted for new therapies.

1 Oct 2020

Study offers explanation for why people's responses to the same drug vary widely

Scientists at Scripps Research have comprehensively mapped how a key class of proteins within cells regulates signals coming in from cell surface receptors.

1 Oct 2020

Scientists map genetic networks that control the biology of regulatory T cells

Unlike most T cells, which launch immune responses against foreign molecules, regulatory T cells are the peacekeepers of the human immune system, damping down inflammatory reactions when they're not needed.

1 Oct 2020

Compounds repurposed from malaria treatment can kill diarrheal pathogen

A class of compounds used for malaria treatment also kill the intestinal parasite Cryptosporidium, a leading cause of diarrheal disease and death in children that has no cure, a multi-institution collaboration of researchers found in a new study.

1 Oct 2020

In-depth analysis of coronavirus genome sequence in Norfolk identifies hidden outbreaks

An in-depth analysis of the genome sequence of coronavirus circulating in Norfolk, UK by researchers at the Quadram Institute and University of East Anglia has mapped the spread of the virus, identified hidden outbreaks and provided insights into the effectiveness of interventions to stop its spread.

1 Oct 2020

Study shows how cancer cells gain access to nerve signal to enter the bloodstream

Tumors come in many shapes and forms--curable or deadly, solid or liquid, lodged inside the brain, bone, or other tissues. One thing they all have in common, however, is a knack for molecular deceit.

1 Oct 2020

Immunotherapy drug improves survival over standard chemotherapy for lung cancer patients

The immunotherapy drug atezolizumab improves survival over standard chemotherapy for many patients with newly diagnosed non-small cell lung cancer (NSCLC), according to a new study led by Yale Cancer Center (YCC) researchers.

1 Oct 2020

Researchers use single-cell sequencing to identify cell types that occur in pancreatic tumors

Led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, and by HonorHealth Research and Innovation Institute, an international team of researchers have described in detail the individual cells that comprise the pancreatic cancer microenvironment, a critical step in devising new treatment options for patients with this aggressive and difficult-to-treat disease.

1 Oct 2020

Patients with invasive lobular carcinoma could benefit from additional adjuvant therapy

New results presented at the 12th European Breast Cancer Conference show that a test, which looks at the activity of 70 genes in breast cancer tissue, is possible to use in the clinic to identify patients with invasive lobular carcinoma (ILC) that is at high risk of recurring and progressing.

1 Oct 2020

Researchers unravel new mechanism of cell survival in chronic lymphocytic leukemia

Researchers at The Wistar Institute unraveled a mechanism employed by chronic lymphocytic leukemia (CLL) cells for their survival.

30 Sep 2020

Study links poorer cognitive performance with greater risk for impaired daily life activities

Subtle differences in cognition may help identify individuals at risk for becoming dependent years later upon others to complete daily activities, such as managing medications or finances and other essential activities.

30 Sep 2020

Genetic News and Research

NIH awards $13.8 million to conduct studies on pre-dementia and Alzheimer's disease

Midges and mosquitoes unlikely to spread SARS-CoV-2

Supporting Coronavirus Research with Liquid Chromatography

Higher prevalence of SARS-CoV-2 with D614G mutation in Washington State

A comprehensive clinical and genetic model for predicting severe COVID-19 risk

Rapid detection of SARS-CoV-2 with portable CRISPR-based mobile phone diagnostic test

Identifying cardiopulmonary processes involved in severe COVID-19

Modeling viral clades improves prediction of COVID-19 growth rates

Shedding light on origin, transmission, spread of COVID-19 in Norfolk

New, rare genetic form of dementia discovered

Study offers explanation for why people's responses to the same drug vary widely

Scientists map genetic networks that control the biology of regulatory T cells

Compounds repurposed from malaria treatment can kill diarrheal pathogen

In-depth analysis of coronavirus genome sequence in Norfolk identifies hidden outbreaks

Study shows how cancer cells gain access to nerve signal to enter the bloodstream

Immunotherapy drug improves survival over standard chemotherapy for lung cancer patients

Researchers use single-cell sequencing to identify cell types that occur in pancreatic tumors

Patients with invasive lobular carcinoma could benefit from additional adjuvant therapy

Researchers unravel new mechanism of cell survival in chronic lymphocytic leukemia

Study links poorer cognitive performance with greater risk for impaired daily life activities

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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