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Mixing COVID vaccines generates a comparable immune response

The validity and safety of mixing first and second doses of different types are explored in a paper recently uploaded to the preprint server medRxiv* by Rose et al. (July 13th, 2021), finding that robust antibody response is induced, comparable to, and perhaps even exceed that generated by homologous dosing.

16 Jul 2021

Water-soluble vitamin E compounds directly inhibit SARS-CoV-2 replication and synergize with remdesivir

Researchers in the United States have shown that water-soluble derivatives of vitamin E (α-tocopherol) exhibit potent antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

15 Jul 2021

New live cell models lay the groundwork for studies into mitochondrial diseases

The mitochondrion has garnered quite the reputation for its role as the "powerhouse of the cell." These tiny, but mighty organelles play various life-sustaining roles, from powering our own cells and organs to fueling chemical and biological processes.

15 Jul 2021

COVID-19 vaccine candidate that can be produced in yeast proves effective in macaques

Researchers in the United States have designed a modular protein subunit vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that elicited a strong immune response in macaques and prevented the animals from developing coronavirus disease 2019 (COVID-19).

15 Jul 2021

Imaging technology may be able to treat life-threatening blood clotting condition

Penn State College of Engineering researchers set out to develop technology capable of localizing and imaging blood clots in deep veins. Turns out their work may not only identify blood clots, but it may also be able to treat them.

15 Jul 2021

COVID-19 researchers review 184 drug repurposing candidates

New research describes the use of integrative bioinformatics analyses of transcriptomic profiles for COVID-19 therapeutics.

15 Jul 2021

Autophagy disruption may be at the root of early cognitive changes in Huntington’s disease

Huntington's Disease (HD) is a progressive neurodegenerative condition characterized by motor, cognitive, and psychiatric symptoms, and motor symptoms are often preceded by cognitive changes.

15 Jul 2021

A rapid, highly accurate test to detect antibodies against SARS-CoV-2 in human serum

Scientists have developed a rapid, highly accurate test to detect antibodies against the spike protein of SARS-CoV-2 in human serum, opening a new avenue for understanding the full extent of the pandemic and evaluating the effectiveness of vaccines.

15 Jul 2021

Researchers study the role of subnuclear NSrp70 in T cell-mediated adaptive immunity

T cells are components of the body’s immune system. The ability of T cells to recognize diverse pathogens and mount a defense against them stems from the way proteins are spliced during their development and maturation.

15 Jul 2021

Potential compounds targeting SARS-COV-2 main protease (in vivo)

Now, new research published in the journal Hippokratia focuses on assisting the ongoing COVID-19 therapeutic research by developing a new method to identify active compounds that have the potential to fight against COVID-19 infection.

15 Jul 2021

Short chain fatty acids have potential therapeutic applications against COVID-19, study suggests

SARS-CoV-2, the virus responsible for the COVID-19 pandemic, is highly transmissible, with nasal passages being the target of original infection.

15 Jul 2021

Research sheds light on a new mechanism for inhibitory synapse specificity in the cortex

Researchers at the Max Planck Florida Institute for Neuroscience have discovered that the cell adhesion protein IgSF11 determines the layer-specific synaptic connectivity of a distinct class of cortical interneurons.

15 Jul 2021

Rapid COVID-19 antibody detection with time‐resolved fluorescence immunoassay

A new study published in the journal Biotechnology and Applied Biochemistry deals with the development of a time-resolved fluorescence immunoassay (TRFIA) for the detection of total COVID-19 antibodies in humans.

15 Jul 2021

A small molecule inhibitor shows promise to reduce the growth of uveal melanoma

Uveal melanoma, or UM, is a rare and deadly cancer of the eye, and the mortality rate has remained unimproved for 40 years. Half of the melanomas spread to other organs of the body, causing death in less than a year, so new treatments to preserve vision and prevent death are an urgent need.

15 Jul 2021

Protein C News and Research

Mixing COVID vaccines generates a comparable immune response

Water-soluble vitamin E compounds directly inhibit SARS-CoV-2 replication and synergize with remdesivir

New live cell models lay the groundwork for studies into mitochondrial diseases

COVID-19 vaccine candidate that can be produced in yeast proves effective in macaques

Imaging technology may be able to treat life-threatening blood clotting condition

COVID-19 researchers review 184 drug repurposing candidates

Autophagy disruption may be at the root of early cognitive changes in Huntington’s disease

A rapid, highly accurate test to detect antibodies against SARS-CoV-2 in human serum

Researchers study the role of subnuclear NSrp70 in T cell-mediated adaptive immunity

Potential compounds targeting SARS-COV-2 main protease (in vivo)

Short chain fatty acids have potential therapeutic applications against COVID-19, study suggests

Research sheds light on a new mechanism for inhibitory synapse specificity in the cortex

Rapid COVID-19 antibody detection with time‐resolved fluorescence immunoassay

A small molecule inhibitor shows promise to reduce the growth of uveal melanoma

Study finds clear association between hemoglobin levels and key cardiovascular traits

Should we be concerned about the SARS-CoV-2 Lambda variant?

A pencil graphite biosensor that detects SARS-CoV-2

Aggressive type of cancer provides clues to how metastases form

New OMV-based COVID-19 vaccine candidate proves effective in mice

Metal-based molecule inhibits the build-up of Alzheimer's peptides in lab tests

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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