B Cell News and Research

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Study expands understanding of the eye's immune response to viral infections

The cornea - the transparent protective outer layer of the eye critical to helping us see – produces a delicate and limited immune response to fight infections without damaging our vision, according to a ground-breaking new study from the Peter Doherty Institute for Infection and Immunity (Doherty Institute).

24 May 2022

Computational modeling fine tunes RBD-1C aptamer against SARS-CoV-2 S protein

Researchers used the SARS-CoV-2 sequence against aptamers to perform the in silico selection of an aptamer against the SARS-CoV-2 S protein.

24 May 2022

UH experts in cloning and stem cell science take the first step toward unraveling cystic fibrosis

Two nationally recognized experts in cloning and stem cell science from the University of Houston are taking the first step toward limiting the consequences of chronic inflammation in cystic fibrosis (CF) by identifying the source of this persistent and enigmatic inflammation in CF lungs.

24 May 2022

Study identifies a gene that plays an important role in embryo development

A new study co-led by a Cedars-Sinai investigator identified a gene that plays an important role in a biological pathway involved in embryo development.

24 May 2022

Study reveals how processes in the human body could turn harmless immune cells into ruthless killers

Processes in the human body could turn groups of harmless immune cells into ruthless killers, capable of attacking other cells infected with viruses or parasites, and potentially tumor cells, a new study reveals.

24 May 2022

Research provides insight into genetic mechanisms of Wilms tumor

New research from Ann & Robert H. Lurie Children's Hospital of Chicago and collaborators from other institutions provides insights into some of the genetic characteristics resulting in the development of relapse in patients with Wilms tumor (nephroblastoma), the most common type of pediatric cancer of the kidney.

24 May 2022

Researcher from The University of Colorado Anschutz Medical Campus to receive DeNovix Platinum Edition CellDrop

DeNovix Inc. is pleased to announce the winner of the Platinum Edition CellDrop Giveaway: Dr. Christina Roark from The University of Colorado Anschutz Medical Campus, USA! Selected at random from thousands of entries from scientists worldwide, the CellDrop will be housed in Dr. Roark’s lab in the Allergy and Clinical Immunology Division in the Department of Medicine.

From DeNovix Inc. 24 May 2022

The impact of SARS-CoV-2 nucleocapsid protein mutations on the performance of rapid antigen tests

The study findings showed that the rapid antigen tests with the DMS approach could accurately identify antibody escape mutations in the SARS-CoV-2 N protein.

24 May 2022

Vaccinated individuals with SARS-CoV-2 infection develop virus-specific T cells inside their noses

In a recent study posted to the medRxiv* preprint server, investigators in Singapore showed that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) breakthrough infection elicited broadly specific virus-selective nasal resident CD8 and CD4 T cells.

24 May 2022

Omicron vaccine breakthrough infections induce potent cross-reactive antibodies

In a recent study published in the journal Cell, researchers demonstrated that antibodies generated due to breakthrough infection (BTI) by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) new variant of concern (VOC) Omicron in vaccinated individuals could neutralize all VOCs.

24 May 2022

Biologic medications used by IBD patients boost COVID-19 vaccine response

Getting the COVID-19 vaccination strengthened one type of immune response to the SARS-CoV-2 virus in inflammatory bowel disease (IBD) patients even though they were taking immunosuppressant medication, according to investigators at Cedars-Sinai.

23 May 2022

BNT162b2 vaccine induces robust SARS-CoV-2 immunity in children

In a recent study posted to the medRxiv* pre-print server, researchers evaluated coronavirus disease 2019 (COVID-19) vaccine-induced humoral immune response in five to 11-year-old children.

23 May 2022

Study sheds light on the molecular biology behind genetic epilepsy

Sometimes, even the alteration of a single nucleotide in a gene can cause serious disease. In a young boy with epilepsy, this kind of mutation has not just affected the functioning of the protein in question – it could also curb the functioning of several closely related proteins.

23 May 2022

ATLAS assay reveals SARS-CoV-2 variant T-cell responses

Researchers utilize the ATLAS screening assay to reveal the antigen response profiles of T-cells to different SARS-CoV-2 variants.

23 May 2022

Using microfluidics and magnets to isolate rare, allergen-reactive white blood cells

Across the world, food allergies are on the rise. One of the most important cells in studying this ailment are basophils, which activate inflammation and other responses to allergens such as rashes, and sometimes, anaphylaxis.

23 May 2022

Penn Medicine and CHOP announce plans with Costa Rica's CCSS for CAR T research

Penn Medicine and Children's Hospital of Philadelphia, who together pioneered the research and development of the world's first personalized cellular therapy for cancer - also known as CAR T cell therapy - have announced plans with Costa Rica's CCSS, or the Caja Costarricense de Seguro Social (Social Security Program), to facilitate CAR T research in Costa Rica.

23 May 2022

Novel genetic test enables earlier, more accurate diagnosis of primary immunodeficiency disorders

Primary immunodeficiency disorders (PID) can result in chronic and sometimes life-threatening infections. More than 450 PIDs have been described, but timely and accurate diagnoses remain a challenge.

23 May 2022

SARS-CoV-2 mRNA vaccines do not stimulate interferon stimulatory gene expression in Aicardi Goutières Syndrome patients

A new study aimed to evaluate the immunostimulatory potential of mRNA vaccines in AGS patients.

23 May 2022

Novel AI algorithm developed for assessing digital pathology data

Digital pathology is an emerging field which deals with mainly microscopy images that are derived from patient biopsies.

23 May 2022

Gabapentin treatment may enhance recovery of movement after a stroke

The drug gabapentin, currently prescribed to control seizures and reduce nerve pain, may enhance recovery of movement after a stroke by helping neurons on the undamaged side of the brain take up the signaling work of lost cells, new research in mice suggests.

23 May 2022

B Cell News and Research

Study expands understanding of the eye's immune response to viral infections

Computational modeling fine tunes RBD-1C aptamer against SARS-CoV-2 S protein

UH experts in cloning and stem cell science take the first step toward unraveling cystic fibrosis

Study identifies a gene that plays an important role in embryo development

Study reveals how processes in the human body could turn harmless immune cells into ruthless killers

Research provides insight into genetic mechanisms of Wilms tumor

Researcher from The University of Colorado Anschutz Medical Campus to receive DeNovix Platinum Edition CellDrop

The impact of SARS-CoV-2 nucleocapsid protein mutations on the performance of rapid antigen tests

Vaccinated individuals with SARS-CoV-2 infection develop virus-specific T cells inside their noses

Omicron vaccine breakthrough infections induce potent cross-reactive antibodies

Biologic medications used by IBD patients boost COVID-19 vaccine response

BNT162b2 vaccine induces robust SARS-CoV-2 immunity in children

Study sheds light on the molecular biology behind genetic epilepsy

ATLAS assay reveals SARS-CoV-2 variant T-cell responses

Using microfluidics and magnets to isolate rare, allergen-reactive white blood cells

Penn Medicine and CHOP announce plans with Costa Rica's CCSS for CAR T research

Novel genetic test enables earlier, more accurate diagnosis of primary immunodeficiency disorders

SARS-CoV-2 mRNA vaccines do not stimulate interferon stimulatory gene expression in Aicardi Goutières Syndrome patients

Novel AI algorithm developed for assessing digital pathology data

Gabapentin treatment may enhance recovery of movement after a stroke

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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