Immune System News and Research

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NLRX1 protein could be new biomarker for colorectal cancer, find UNC Lineberger researchers

UNC Lineberger Comprehensive Cancer Center researchers have discovered that a deficiency in a key protein that regulates immune system warning signals could be a new biomarker for colorectal cancer, the second largest cancer killer in the United States. They believe the marker could be used to gauge response to a potential new treatment for the disease.

11 Mar 2016

Springing forward one hour may lead to increased heart attack risk

Many people may groan about losing an hour of sleep March 13, but there may be a more serious reason to be mindful of daylight saving time.

11 Mar 2016

STING agonists developed to induce cellular death in B cell malignancies

In almost every mammalian cell, you will find the endoplasmic reticulum, a network of continuous membranes responsible for controlling metabolism as well as the folding, assembly and secretion of proteins.

11 Mar 2016

Maternal bacterial infections affect fetal brain anatomy and cognitive functioning after birth

St. Jude Children's Research Hospital scientists have discovered how pieces of bacterial cell wall cross the placenta and enter developing neurons, altering fetal brain anatomy and cognitive functioning after birth. The study appears today in the scientific journal Cell Host & Microbe.

10 Mar 2016

New procedure allows kidney transplants from incompatible donors

Researchers have found a way to stop patients rejecting kidneys that have come from incompatible donors, potentially slashing the waiting time for thousands of people in desperate need of the procedure.

10 Mar 2016

Popular kidney cancer drugs do not reduce incidence of recurrence

Two widely used targeted therapy drugs approved by the FDA for the treatment of metastatic kidney cancer—sorafenib and sunitinib—are no more effective than a placebo in preventing return of the disease to increase life spans of patients suffering from advanced kidney cancer after surgery, according to a new multi-institutional study in the Lancet led by a researcher at the Abramson Cancer Center (ACC) of the University of Pennsylvania.

10 Mar 2016

BioLineRx announces year end 2015 financial results, provides operational update

BioLineRx Ltd., a clinical-stage biopharmaceutical company dedicated to identifying, in-licensing and developing promising therapeutic candidates, today reported its financial results for the year ended December 31, 2015.

10 Mar 2016

Low cost, easy-to-use test could help reduce TB death rate of HIV patients in sub-Saharan Africa

A low cost, easy to use, urine test to diagnose tuberculosis (TB) among patients with HIV could help reduce the TB death rate of HIV-positive patients in hospital, according to a new study published in The Lancet today.

10 Mar 2016

CWRU researcher to customize tobacco mosaic virus to treat human cancers

A Case Western Reserve University researcher has been awarded more than $3 million in federal and foundation grants to turn common plant viruses into cancer sleuths and search-and-destroy emissaries.

10 Mar 2016

New, regenerative medicine approach developed to remove congenital cataracts in infants

Researchers at University of California, San Diego School of Medicine and Shiley Eye Institute, with colleagues in China, have developed a new, regenerative medicine approach to remove congenital cataracts in infants, permitting remaining stem cells to regrow functional lenses.

10 Mar 2016

VIGH study seeks to eliminate mother-to-child transmission of HIV in Africa

Mother-to-child transmission of the human immunodeficiency virus (HIV), which causes AIDS, is still a major problem in resource-limited, rural areas of the world where health care providers are scarce.

10 Mar 2016

Vanderbilt investigators isolate human antibodies against H7 bird flu

Researchers at Vanderbilt University Medical Center have isolated human antibodies against a type of bird flu that has killed more than 200 people in China since 2012 and which may pose a worldwide pandemic threat.

10 Mar 2016

Study reveals direct regulatory role of serotonin in rheumatoid arthritis

For the first time, serotonin (5-hydroxytryptamine, 5-HT) has been directly implicated in the pathophysiology of rheumatoid arthritis (RA). Although 5-HT is predominantly known as a neurotransmitter within the central nervous system, new evidence points to additional important functions for serotonin in the periphery.

10 Mar 2016

Regulatory immune cells compromised in PAH

Research suggests that regulatory T cells may play a part in all subtypes of pulmonary arterial hypertension.

10 Mar 2016

HIV-positive individuals in Africa with certain genetic variant have lower chance of developing TB

In the first known discovery of its kind, a Case Western Reserve University School of Medicine-led team has found that HIV patients in Africa with a certain genetic variant have a 63-percent lower chance of developing tuberculosis than HIV patients without the genetic variant.

10 Mar 2016

Hematopoietic reprogramming can lead to differentiated blood products for cell-replacement therapy

Building upon previous work, researchers at the Icahn School of Medicine at Mount Sinai identified cells in the embryos of mice that are precursors to blood stem cells or hematopoietic stem/progenitor cells.

9 Mar 2016

Nociceptin could help to reduce effects of asthma attacks

An international team of researchers from the Universities of Leicester and Naples has examined the role of a receptor in the body that could help to prevent or reduce the effects of asthma attacks.

9 Mar 2016

Metabolic syndrome treatment benefits MS patients

Oral antidiabetic medications have beneficial anti-inflammatory effects in patients with multiple sclerosis and metabolic syndrome, providing support for a link between metabolism and autoimmunity, researchers report.

9 Mar 2016

Changes in gut bacteria strongly associated with PCOS-related obesity

Modifying gut bacteria could be a treatment option for some of the symptoms associated with the widespread disease polycystic ovary syndrome (PCOS), according to a recent study by San Diego State University researchers in collaboration with investigators from the University of California, San Diego.

8 Mar 2016

Research findings may provide highly effective therapeutic strategy for treatment of Alzheimer's, AMD

For the first time, researchers at LSU Health New Orleans have shown that a protein critical to the body's ability to remove waste products from the brain and retina is diminished in age-related macular degeneration, after first making the discovery in an Alzheimer's disease brain. The research team, led by Walter Lukiw, PhD, Professor of Neurology, Neuroscience and Ophthalmology at LSU Health New Orleans Neuroscience Center, also discovered a key reason, identifying a new treatment target.

8 Mar 2016

Immune System News and Research

NLRX1 protein could be new biomarker for colorectal cancer, find UNC Lineberger researchers

Springing forward one hour may lead to increased heart attack risk

STING agonists developed to induce cellular death in B cell malignancies

Maternal bacterial infections affect fetal brain anatomy and cognitive functioning after birth

New procedure allows kidney transplants from incompatible donors

Popular kidney cancer drugs do not reduce incidence of recurrence

BioLineRx announces year end 2015 financial results, provides operational update

Low cost, easy-to-use test could help reduce TB death rate of HIV patients in sub-Saharan Africa

CWRU researcher to customize tobacco mosaic virus to treat human cancers

New, regenerative medicine approach developed to remove congenital cataracts in infants

VIGH study seeks to eliminate mother-to-child transmission of HIV in Africa

Vanderbilt investigators isolate human antibodies against H7 bird flu

Study reveals direct regulatory role of serotonin in rheumatoid arthritis

Regulatory immune cells compromised in PAH

HIV-positive individuals in Africa with certain genetic variant have lower chance of developing TB

Hematopoietic reprogramming can lead to differentiated blood products for cell-replacement therapy

Nociceptin could help to reduce effects of asthma attacks

Metabolic syndrome treatment benefits MS patients

Changes in gut bacteria strongly associated with PCOS-related obesity

Research findings may provide highly effective therapeutic strategy for treatment of Alzheimer's, AMD

Understanding the DNA Damage Response in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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