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Pig kidney transplant breakthrough uncovers immune rejection secrets

Researchers have uncovered and then overcome an obstacle that has led to the failure of pioneering efforts in xenotransplantation, in which an animal kidney is transplanted into a human.

13 Nov 2025

Innovative research reveals FGD3 as a key player in breast cancer cell death

A naturally occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the effectiveness of some anticancer agents, including doxorubicin, one of the most widely used chemotherapies, and a preclinical drug known as ErSO, researchers report.

13 Nov 2025

Study links common Epstein-Barr virus to autoimmune lupus

One of humanity's most ubiquitous infectious pathogens bears the blame for the chronic autoimmune condition called systemic lupus erythematosus or, colloquially, lupus, Stanford Medicine investigators and their colleagues have found.

12 Nov 2025

Stanford scientists discover unexpected cancer resistance in aged mice

Old laboratory mice develop substantially fewer and less-aggressive lung tumors than younger animals in a new study led by Stanford University researchers.

12 Nov 2025

Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory

Replacing APOE4 with APOE2 in adult mice rapidly reshapes brain lipids and gene expression, even after development is complete. This switch, especially when targeted to astrocytes, reduces amyloid burden, dampens gliosis, and improves associative memory despite E2-like peripheral lipid risks.

12 Nov 2025

Study: Biological underpinnings of autism and ADHD may transcend traditional diagnostic boundaries

A new study published in Molecular Psychiatry reveals that the biological underpinnings of autism and ADHD may transcend traditional diagnostic boundaries.

12 Nov 2025

Shift Bioscience publishes improved metric calibration framework for robust genetic perturbation modeling using AI Virtual Cells

Shift Bioscience (Shift), a biotechnology company uncovering the biology of cell rejuvenation to end the morbidity and mortality of aging, today announced the release of new research detailing an improved framework for evaluating benchmark metric calibration in virtual cell models. U

From Shift Bioscience 11 Nov 2025

AI chat box helps investigate complex biology in English language

Using sophisticated RNA sequencing technology, biomedical researchers can measure the activity of our genes across millions of single cells, creating detailed maps of tissues, organs, and diseases.

11 Nov 2025

Long non-coding RNA MALAT1 linked to progression and spread of triple-negative breast cancer

When researchers look for potential cancer therapy targets, they typically go after protein-coding genes that participate in disease progression. Disrupt them and negate whatever role they play in cancer's development or spread.

11 Nov 2025

Shared genetic roots connect neurological and psychiatric disorders

In a groundbreaking study, researchers from the Centre for Precision Psychiatry at the University of Oslo and Oslo University Hospital have discovered extensive genetic links between neurological disorders like migraine, stroke and epilepsy, and psychiatric illnesses such as schizophrenia and depression.

11 Nov 2025

Nanoparticle vaccine eliminates HPV-induced tumors in animal model

A nanoparticle vaccine designed to fight cancers induced by human papillomavirus (HPV) eradicated tumors in an animal model of late-stage metastatic disease, UT Southwestern Medical Center scientists report in a new study published in the Proceedings of the National Academy of Sciences (PNAS).

11 Nov 2025

Targeting RNA splicing errors protects against tau-induced neurodegeneration

Alzheimer's Disease (AD), the leading cause of dementia, affects nearly 40 million individuals globally, resulting in a gradual loss of memory and independence. Despite extensive research over the past decades, no treatments have been found that can halt or reverse the progression of this devastating disease.

11 Nov 2025

Study advances the possibility of age-based pancreatic cancer treatment

While some risk factors for cancer can be mitigated through lifestyle choices such as diet or exercise, aging is not one of them. In the case of pancreatic cancer, it also can limit treatment options if a patient is too frail to be safely treated with surgery or other alternatives.

10 Nov 2025

One-time CRISPR therapy safely lowers cholesterol and triglycerides in early trial

In a 15-patient, Phase 1 one, first-in-human trial, a one-time, CRISPR-Cas9 gene-editing therapy safely reduced LDL cholesterol and triglycerides in people with difficult-to-treat lipid disorders, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

Weill Cornell scientists discover early step in fat cell inflammation leading to diabetes

Weill Cornell Medicine investigators have identified an early step in a cellular process that leads to inflammation in fat cells and may result in type 2 diabetes in people with obesity.

10 Nov 2025

New diagnostic approach identifies dementia stages based on neurovascular and metabolic changes

Researchers from the Indiana University School of Medicine have developed a highly sensitive diagnostic that predicts a person's stage of dementia based on neurovascular and metabolic changes.

10 Nov 2025

Exploring cost-effective approaches to detecting familial hypercholesterolemia in children

In the United States, one in every 250 people has inherited a genetic variant that leads to dangerously high cholesterol levels from birth.

10 Nov 2025

Maternal type 1 diabetes may protect children from developing the disease

Findings suggest maternal T1D exposure leads to protective epigenetic alterations in children, influencing immune response and type 1 diabetes susceptibility.

10 Nov 2025

Drinking orange juice daily may fine-tune genes tied to cardiovascular wellness

Regular orange juice consumption reprograms immune-cell gene activity linked to blood pressure, lipid metabolism, and inflammation in healthy adults. The molecular effects differ by body weight, suggesting BMI-tailored benefits from this everyday beverage.

9 Nov 2025

Studies uncover two novel, critical strategies for bacterial surface movement

New studies from Arizona State University reveal surprising ways bacteria can move without their flagella - the slender, whip-like propellers that usually drive them forward.

8 Nov 2025

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Genes News and Research

Pig kidney transplant breakthrough uncovers immune rejection secrets

Innovative research reveals FGD3 as a key player in breast cancer cell death

Study links common Epstein-Barr virus to autoimmune lupus

Stanford scientists discover unexpected cancer resistance in aged mice

Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory

Study: Biological underpinnings of autism and ADHD may transcend traditional diagnostic boundaries

Shift Bioscience publishes improved metric calibration framework for robust genetic perturbation modeling using AI Virtual Cells

AI chat box helps investigate complex biology in English language

Long non-coding RNA MALAT1 linked to progression and spread of triple-negative breast cancer

Shared genetic roots connect neurological and psychiatric disorders

Nanoparticle vaccine eliminates HPV-induced tumors in animal model

Targeting RNA splicing errors protects against tau-induced neurodegeneration

Study advances the possibility of age-based pancreatic cancer treatment

One-time CRISPR therapy safely lowers cholesterol and triglycerides in early trial

Weill Cornell scientists discover early step in fat cell inflammation leading to diabetes

New diagnostic approach identifies dementia stages based on neurovascular and metabolic changes

Exploring cost-effective approaches to detecting familial hypercholesterolemia in children

Maternal type 1 diabetes may protect children from developing the disease

Drinking orange juice daily may fine-tune genes tied to cardiovascular wellness

Studies uncover two novel, critical strategies for bacterial surface movement

eBook: Using iPSCs models for human disease research and drug discovery eBook

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