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Global breast cancer burden rising fastest in low-income countries

Despite recent advancements in breast cancer treatments, new breast cancer cases in women are predicted to rise by a third globally from 2.3 million in 2023 to more than 3.5 million in 2050.

2 Mar 2026

Experts identify safest and most effective diets for IBS management

This review in Nutrients evaluates the scientific evidence, clinical effectiveness, and safety of major dietary strategies for irritable bowel syndrome, including traditional advice, low-FODMAP, gluten-free, Mediterranean, and starch- and sucrose-reduced diets. It concludes that while the low-FODMAP diet has the strongest short-term evidence, no single approach fits all patients, and dietitian-led personalization is essential.

2 Mar 2026

Study reveals cellular and metabolic landscape of lymph node metastasis in breast cancer

A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast cancer reveals novel mechanisms of the metabolic-immune interaction that drive the spread of breast cancer.

2 Mar 2026

Experts call for rapid improvements in diagnosis, treatment of bile duct cancer

The international group of experts, including Professor John Bridgewater (UCL Cancer Institute), is calling for rapid improvements in diagnosis, treatment and research for cholangiocarcinoma, also known as bile duct cancer.

2 Mar 2026

NLRP3 inflammasome plays dual, time-dependent roles during acute wound healing

Wound healing is a multistep biological process involving inflammation, tissue formation, and remodeling.

2 Mar 2026

Accelerating rare disease diagnosis with Mondo

Coryssa Barnes, of Henderson, N.C., welcomed her first child, Ezra, in 2020. At four months old, he was unable to sit without support. As time went on, he failed to reach other developmental milestones, prompting his worried parents to consult several medical experts.

2 Mar 2026

Wisdom Bioscience establishes Scientific Advisory Board to advance oral cancer diagnostics and screening

Wisdom Bioscience, Inc., a biotechnology company pioneering non-invasive oral cancer diagnostics, today announced the formation of its Scientific Advisory Board (SAB) following the close of an initial funding round.

2 Mar 2026

Forecasting disease intensity through genomic risk

Approximately 60,000 Danes live with chronic inflammatory bowel disease. Some experience limited discomfort, while others go through a debilitating disease course involving surgery and a stoma. Add to this the fear of leaving home due to urgent toilet needs.

2 Mar 2026

Higher tyrosine levels linked to shorter lifespan in major UK Biobank analysis

Researchers analyzed over 272,000 UK Biobank participants and used Mendelian randomization to investigate whether circulating phenylalanine and tyrosine influence lifespan. Genetically predicted higher tyrosine levels were linked to shorter lifespan, particularly in men, while phenylalanine showed no independent effect after adjustment.

1 Mar 2026

Mendelian randomization study reveals opposing roles for IL6 and IL6R in long-term mortality

A new research paper was published in Volume 18 of Aging-US on February 6, 2026, titled "Causal effects of inflammation on long-term mortality: a Mendelian randomization study."

27 Feb 2026

Genomic landscape and clinicopathologic significance of POLE mutant colorectal carcinoma

DNA polymerase epsilon catalytic subunit A (POLE) gene plays a crucial role in DNA repair and chromosomal replication.

27 Feb 2026

New biomarkers for targeted gastric therapy

HER2-positive gastric cancer accounts for a substantial proportion of advanced cases and has long been treated with HER2-targeted therapies. While trastuzumab deruxtecan has shown superior activity compared with earlier agents, most patients either fail to respond initially or eventually develop resistance.

26 Feb 2026

Serial liquid biopsies reveal evolution in advanced prostate cancer

A new study using serial liquid biopsies to track how metastatic prostate cancer evolves under treatment pressure showed that androgen receptor (AR) alterations consistently emerged and were linked to poorer outcomes across therapies.

26 Feb 2026

Extra copies of chromosome 1q may play key role in the earliest stages of pancreatic cancer

Researchers at the Johns Hopkins Kimmel Cancer Center and its Ludwig Center uncovered new evidence that extra copies of a specific chromosome segment - chromosome 1q - may play a key role in the earliest stages of pancreatic cancer development.

26 Feb 2026

Smoking triggers epigenetic damage linked to macular degeneration

Through a series of experiments supported by the National Institutes of Health, Johns Hopkins Medicine (JHM) researchers say they have advanced understanding of how smoking damages the eye and contributes to the development of age-related macular degeneration (AMD), the leading worldwide cause of visual impairment and blindness among people 50 and older.

26 Feb 2026

New method clarifies whether NOTCH1 variants cause congenital heart defects

One to two out of every 100 newborn babies are born with a Congenital Heart Defect (CHD), yet the exact cause remains unclear.

26 Feb 2026

Genetic switch MafB enables macrophages to reach full maturity and preserve organ health

Researchers at the University of Liège have identified a key genetic regulator that enables macrophages to reach full maturity and preserve the health of our organs.

26 Feb 2026

New laser technique ensures integrity of mRNA therapeutics

Messenger RNA (mRNA) technology is transforming medicine by providing our cells with genetic instructions to produce proteins that help the immune system prevent or fight a wide range of diseases, including cancer and other rare disorders.

26 Feb 2026

Neanderthal DNA loss tied to ancient interbreeding dynamics

The human genome is a rich, complex record of migration, encounters, and inheritance written over thousands of millennia.

26 Feb 2026

Jumping DNA fragments found to destabilize cancer genome

A study published today in the journal Science reveals how jumping fragments of human DNA, a type of genetic parasite, destabilise the cancer genome. Unstable genomes are a fertile playground for cancer evolution, giving malignant cells more opportunities to grow, adapt and evade treatment.

26 Feb 2026