Mitochondria News and Research

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Early marker of cardiac damage triggered by cancer treatment identified

Every year, 4 million new cases of cancer are diagnosed in Europe. Advances in cancer treatment sometimes come at the cost of major adverse effects, and one of the most prominent is cardiotoxicity. Myocardial toxicity affects as many as 25% of patients undergoing treatment with commonly used anticancer drugs.

19 Feb 2019

Activating gene that helps excite neurons reverses depression in male mice

Directly activating a gene important to exciting our excitatory neurons and associated with major depression may help turn around classic symptoms like social isolation and loss of interest, at least for males, scientists report.

18 Feb 2019

Low-calorie meals have protective effect against some diseases, reveals research

The number of calories a person eats directly influences the performance of different cells. A group of researchers from the University of São Paulo has shown that low-calorie meals have a protective effect against some diseases.

13 Feb 2019

Newly discovered genetic disorder opens way for future diabetes drugs

Knowledge of a newly discovered genetic disorder, which means that a person cannot produce the protein TXNIP (thioredoxin interacting protein) in their cells, can open for the development of new diabetes drugs.

12 Feb 2019

Study reveals how one mutation causes the most common inherited intellectual disability

Research published today (Feb. 11, 2019) reveals how one mutation causes fragile X, the most common inherited intellectual disability.

12 Feb 2019

New 'WormJam model' could provide valuable insights into human aging

What can worms tell us about human aging? A lot more than you'd think; as research led by the Babraham Institute but involving researchers from multiple disciplines drawn together from across the world has shown.

7 Feb 2019

Rare stem cell may be the root of all metastatic cancers

Researchers have discovered a rogue stem cell that could be the cause of all metastatic cancers. The breakthrough could affect all future research projects.

6 Feb 2019

Researchers find 'origin' of cancer spread

The discovery of the cell, which they are calling 'the cell of origin' sheds new light on what fuels cancer growth and how to potentially stop it.

4 Feb 2019

Tumor-fighting protein also promotes cancer growth, shows study

Search for a description of "p53" and it becomes clear that this human protein is widely known for its cancer-fighting benefits, leading to its renown as "the guardian of the genome."

1 Feb 2019

Researchers unlock key process in human cells that contributes to cancer, neurodegenerative diseases, and aging

Monash researchers have unlocked a key process in all human cells that contributes to diseases like cancer and neurodegenerative diseases as well as ageing.

24 Jan 2019

Synthetic compound from flaxseed can improve heart function in mice with sepsis

Sepsis is a life-threatening systemic inflammatory condition that develops in response to infection. One of its major complications is cardiovascular dysfunction, in which deterioration of the heart muscle, driven by decreased energy production resulting from reduced oxygen and nutrient supplies, frequently ends in organ failure.

23 Jan 2019

Placenta adapts and compensates when pregnant mothers have poor diets or low oxygen

Cambridge researchers have discovered the placenta regulates how much oxygen and nutrients it transports to babies during challenging pregnancies in a study using mice to model conditions in the womb.

21 Jan 2019

Newly discovered regulatory mechanism helps control fat metabolism

A newly discovered regulatory mechanism helps the body control the rate of fat metabolism, according to a new study publishing on January 17 in the open-access journal PLOS Biology by Ligong Chen of Tsinghua University in Beijing and colleagues.

18 Jan 2019

Researchers describe new behavior in energy metabolism that refutes existing evidence

Researchers from the Catalonian Institute of Bioengineering and the Seville Chemical Research Institute have described a new method for the transmission of electrons between proteins that refutes the evidence from experiments until now.

17 Jan 2019

Pre-injury exercise reduces damage to both muscles and nerves, study finds

Exercise can protect both muscle and nerves from damage caused by the restoration of blood flow after injury or surgery, new research from the University of Virginia School of Medicine shows.

17 Jan 2019

Research finds decline in ketone body utilization when coronary circulation is reduced

Ketone bodies are metabolites that can be used as energy sources like glucose and fatty acids. They can be converted into acetyl-CoA, which produces energy via the Krebs cycle in the mitochondria, and are typically used as an alternative energy source during starvation, fasting, or periods of high-intensity exercise.

17 Jan 2019