Next generation sequencing NGS News and Research

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Caliper Life Sciences third quarter GAAP revenue decreases 8% to $29.7 million

Caliper Life Sciences, Inc., today reported results for its third quarter ended September 30, 2010. Third quarter GAAP revenue decreased 8% to $29.7 million from $32.2 million in the same period in 2009 as a result of divestitures in 2010 and 2009. Revenue from on-going business increased 10% on a reported basis and 11% on an organic basis.

28 Oct 2010

1000 Genomes Project publishes comprehensive map of genetic variations in Nature journal

Small genetic differences between individuals help explain why some people have a higher risk than others for developing illnesses such as diabetes or cancer. Today in the journal Nature, the 1000 Genomes Project, an international public-private consortium, published the most comprehensive map of these genetic differences, called variations, estimated to contain approximately 95 percent of the genetic variation of any person on Earth.

28 Oct 2010

Study: lncRNA are involved in host response to viral infection

Scientists have demonstrated for the first time that a certain class of RNA (known as long non-protein-coding RNA [lncRNA]) are involved in the host response to viral infection. These findings, published today in the online journal mBio-, could greatly change the way scientists look at the body's response to viral infection.

27 Oct 2010

Addition of ECC probe to SOLiD System's chemistry achieves greater than 99.99% single-read accuracy

Life Technologies Corporation a provider of innovative life science solutions, today announced that it has established a new standard in accuracy for next generation sequencing. By adding an Exact Call Chemistry (ECC) proprietary probe to its market leading ligation chemistry, the company has demonstrated greater than 99.99% average single-read accuracy.

27 Oct 2010

Golden Helix accelerates copy number variation detection methodology

Golden Helix, Inc., today announced the incorporation of technologies that will greatly accelerate genetic research. By enabling the company's SNP & Variation Suite software to run on off-the-shelf video graphics cards, or GPUs, operations that took hours or days can now be completed in a fraction of the time - and without the need for expensive compute clusters or resorting to cloud-based computing. This novel ability will dramatically accelerate many forms of computationally expensive genetic analyses, including that of next generation sequencing data.

27 Oct 2010

Long non-protein coding RNAs respond to SARS virus infection, says study

For the first time, scientists have discovered that a poorly understood class of RNA produced in a mammal's cells during a respiratory virus attack may affect the outcome of the infection. Their findings are reported today in mBio, a journal of the American Society for Microbiology.

27 Oct 2010

Helicos names Illumina and Life Technologies as additional defendants in lawsuit against Pacific Biosciences

Helicos BioSciences Corporation announced today that it has amended its lawsuit against Pacific Biosciences of California, Inc. for patent infringement by naming Illumina, Inc. and Life Technologies Corporation as additional defendants.

From Illumina, Inc. 25 Oct 2010

New mechanism controlling transmission of abnormal signal at origin of several cancers identified

Researchers at the Institute for Research in Immunology and Cancer (IRIC) of the Universit- de Montr-al have identified a new mechanism controlling the transmission of an abnormal signal at the origin of several cancers. In an article published in the journal Cell, Marc Therrien's team explains the recent discovery of a protein complex that controls the RAS/MAPK signalling pathway, responsible for some of the deadliest cancers, including pancreatic, colon and lung cancers, and melanomas.

21 Oct 2010

New immunoSEQ bioinformatics software platform helps monitor adaptive immune system

Adaptive TCR Technologies, a biotech firm based in Seattle, WA, announced today the release of its immunoSEQ profiling service and immunoSEQ Analyzer bioinformatics software platform. Together, these tools provide researchers and clinicians the ability to profile and monitor the adaptive immune system at a level of detail that has never before been possible.

21 Oct 2010

BIOBASE introduces Genome Trax Next Generation Sequencing solution

BIOBASE announced today that it is entering the Next Generation Sequencing (NGS) market with the launch of a new solution. Genome Trax™ enables researchers to identify genome variations of functional significance by mapping them to known elements such as gene regulatory sites and disease-linked mutations.

13 Oct 2010

Exiqon introduces on-line microRNA qPCR assay design software

Exiqon A/S, a leading supplier of high-value gene expression analysis products, today announced the extension of the miRCURY LNA microRNA PCR product line with the launch of a novel bioinformatics software for the design of custom qPCR assays for microRNA quantification.

12 Oct 2010

IntegenX receives DTRA contract to develop ISS system for rapid detection of emerging pathogens

IntegenX, Inc. today announced that it has been awarded a new contract by the Defense Threat Reduction Agency (DTRA) of the U.S. Department of Defense (DoD) to develop an Integrated Sample-to-Sequence (ISS) system for rapid detection and identification of genetically engineered bacteria and viruses, medically relevant bacteria and viruses, and emerging pathogens.

11 Oct 2010

GeneGo integrates SDM platform with MetaCore and MetaDrug

GeneGo, Inc., a leading provider of databases, software and services in systems biology and chemistry, announced today that they have integrated GenomeQuest's Sequence Data Management (SDM) platform with GeneGo's MetaCore and MetaDrug.

8 Oct 2010

Agilent introduces SureSelect Kinome Target Enrichment Kit to focus next-generation sequencing studies

Agilent Technologies Inc. today introduced the SureSelect Kinome Target Enrichment Kit, enabling researchers to focus next generation sequencing studies on expressed kinases (the kinome). Researchers increasingly are looking at human kinases as a rich, proven source of biomarkers as well as potential drug targets for cancers and other diseases.

30 Sep 2010

Omicsoft's Next Generation Sequencing tools integrated with GeneGo's MetaCore data mining suite

GeneGo, Inc., the leading systems biology tools company and Omicsoft Corporation, the leader in the OMIC repository and analysis field, announced today integration of Omicsoft's Next Generation Sequencing tools with GeneGo's MetaCore data mining suite.

29 Sep 2010

Researchers unveil mechanism of candida infections

More than half of all people are hosts to Candida albicans in their bodies. This species might be located on their skin or mucous membranes or in the intestines frequently without causing any symptoms. However, it can be dangerous to patients whose immunological system has been weakened such as after organ transplants or chemotherapy with cancer. Then, this fungus penetrates into deeper layers of tissue and uses the blood system to spread throughout the body. In Germany alone, several thousand people die from systemic candida infections every year.

29 Sep 2010

Covaris enters co-marketing partnership with Illumina for DNA shearing technologies

Covaris Inc. today announced that it has signed a co-marketing agreement with Illumina, Inc. making Covaris DNA shearing technologies the recommended method of shearing with Illumina next-generation sequencing product lines, including HiSeq, HiScanSQ, and Genome Analyzer.

From Illumina, Inc. 29 Sep 2010

NEB receives SBIR funding to develop novel enzymatic reagents for epigenetic studies

New England Biolabs (NEB) has announced that it has received fast track SBIR funding of $1.22 million to fund the research and development of novel enzymatic reagents for epigenetic studies.

From New England Biolabs 16 Sep 2010

NHGRI announces fund to develop third generation DNA sequencing technologies

More than $18 million in grants to spur the development of a third generation of DNA sequencing technologies was announced today by the National Human Genome Research Institute (NHGRI). The new technologies will sequence a person's DNA quickly and cost-effectively so it routinely can be used by biomedical researchers and health care workers to improve the prevention, diagnosis and treatment of human disease.

14 Sep 2010

Good Start Genetics $18 million Series A financing round co-led by Safeguard Scientifics

Safeguard Scientifics, Inc., a holding company that builds value in growth-stage life sciences and technology companies, today announced that it has co-led a $18 million Series A financing round for Good Start Genetics, Inc. with OrbiMed Advisors, LLC and SV Life Sciences Advisers LLP.

10 Sep 2010

Next generation sequencing NGS News and Research

Caliper Life Sciences third quarter GAAP revenue decreases 8% to $29.7 million

1000 Genomes Project publishes comprehensive map of genetic variations in Nature journal

Study: lncRNA are involved in host response to viral infection

Addition of ECC probe to SOLiD System's chemistry achieves greater than 99.99% single-read accuracy

Golden Helix accelerates copy number variation detection methodology

Long non-protein coding RNAs respond to SARS virus infection, says study

Helicos names Illumina and Life Technologies as additional defendants in lawsuit against Pacific Biosciences

New mechanism controlling transmission of abnormal signal at origin of several cancers identified

New immunoSEQ bioinformatics software platform helps monitor adaptive immune system

BIOBASE introduces Genome Trax Next Generation Sequencing solution

Exiqon introduces on-line microRNA qPCR assay design software

IntegenX receives DTRA contract to develop ISS system for rapid detection of emerging pathogens

GeneGo integrates SDM platform with MetaCore and MetaDrug

Agilent introduces SureSelect Kinome Target Enrichment Kit to focus next-generation sequencing studies

Omicsoft's Next Generation Sequencing tools integrated with GeneGo's MetaCore data mining suite

Researchers unveil mechanism of candida infections

Covaris enters co-marketing partnership with Illumina for DNA shearing technologies

NEB receives SBIR funding to develop novel enzymatic reagents for epigenetic studies

NHGRI announces fund to develop third generation DNA sequencing technologies

Good Start Genetics $18 million Series A financing round co-led by Safeguard Scientifics

How to optimize sample preparation for NGS? eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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