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Novel treatment combination helps combat hard-to-treat pediatric neuroblastoma

For seven months, three-year-old Emil Abbasov underwent chemotherapy to fight the tangerine-sized, cancerous tumor growing in his abdomen. But each time, the tumor resisted harder. Each time, he felt more side effects.

6 Jun 2016

New research reveals advances that could change gynecologic cancer standard-of-care treatments

Advances that could change gynecologic cancer standard-of-care treatments are the centerpiece of key studies being presented by researchers from The University of Texas MD Anderson Cancer Center's Department of Gynecologic Oncology and Reproductive Medicine at the 2016 Annual Meeting of the American Society of Clinical Oncology.

6 Jun 2016

Mastectomy followed by standard therapy improves survival in stage IV breast cancer patients

Surgery to remove the primary tumor in women diagnosed with stage IV breast cancer, followed by the standard combination of therapies, adds months to the patients' lives, compared with standard therapy alone, an international clinical trial led by a University of Pittsburgh Cancer Institute professor revealed.

4 Jun 2016

Earlier surgery may be better for early-onset Type 2 diabetes

Research suggests that prompt surgical intervention may maximise the chances of patients with early-onset Type 2 diabetes achieving remission.

3 Jun 2016

Mortality risk proportional to PPM severity in aortic value surgery

Prosthesis-patient mismatch during surgical aortic valve replacement is associated with a perioperative mortality risk that increases with increasing PPM severity, study findings indicate.

3 Jun 2016

Clinical study finds two topical skin creams as effective noninvasive treatments for low-risk superficial BCC

Basal cell carcinoma is one of the most common cancers and its incidence is increasing worldwide, putting a significant burden on health services. Topical treatments are available for superficial basal cell carcinoma (BCC) but there has a lack of long-term follow-up data to guide treatment decisions.

3 Jun 2016

Scientists use new technique to repair fibrotic liver cells within the organ

Advances in stem cell research have made it possible to convert patients' skin cells into heart cells, kidney cells, liver cells and more in the lab dish, giving researchers hope that one day such cells could replace organ transplantation for patients with organ failure.

3 Jun 2016

Immunotherapy with experimental monoclonal antibody could reduce neuroblastoma tumors

Neuroblastoma tumors shrank, some dramatically, in 80 percent of newly diagnosed, young, high-risk patients enrolled in a Phase II clinical trial that included an experimental monoclonal antibody. The immunotherapy agent was produced on the St. Jude Children's Research Hospital campus where the study is still underway.

3 Jun 2016

Common genetic variant in HO-1 gene linked to AKI risk following cardiac surgery

Testing for a common genetic variant may help reveal which patients face an increased risk of developing kidney damage following heart surgery. The findings, which come from a study appearing in an upcoming issue of the Journal of the American Society of Nephrology, may help investigators develop therapeutic strategies to mitigate this damage.

3 Jun 2016

Retroviral replicating vector can extend lives of brain cancer patients

Doctors at UCLA, Cleveland Clinic, University of California San Diego School of Medicine and additional institutions have achieved a milestone in the development of a treatment for people with recurrent glioblastoma, the most common and aggressive form of brain cancer, by successfully demonstrating a modified virus that can extend the lives of patients with the disease.

2 Jun 2016

Some women with ovarian cancer do not receive beneficial surgical treatment, study finds

Nearly 20 percent of women with ovarian cancer do not undergo surgery, despite it being a standard part of treatment recommendations, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

2 Jun 2016

Severe obesity may contribute to infection risk after bypass surgery

Severely obese patients who undergo a coronary artery bypass are more likely to develop an infection after surgery and stay in hospital longer, compared with people of normal weight, according to a study published in the Journal of the American Heart Association.

2 Jun 2016

Scientists reveal how ER+ breast cancer uses cholesterol-based molecule to evade anti-hormone treatments

New research funded by Breast Cancer Now has identified how the most common breast cancers could be using a cholesterol-based molecule to evade standard anti-hormone treatments, causing patients’ disease to return.

2 Jun 2016

RSI-MRI imaging technology can effectively differentiate aggressive prostate cancer

Physicians have long used magnetic resonance imaging (MRI) to detect cancer but results of a University of California San Diego School of Medicine study describe the potential use of restriction spectrum imaging (RSI) as an imaging biomarker that enhances the ability of MRI to differentiate aggressive prostate cancer from low-grade or benign tumors and guide treatment and biopsy.

2 Jun 2016

Deployed military soldiers three times more likely to suffer non-combat musculoskeletal injuries

Since September 11, 2001, an estimated 60,000 U.S. military service members have been injured in combat during the Afghanistan and Iraq wars. Nearly 45,000 of all combat injuries are caused by improvised explosive devices, also known as IEDs.

2 Jun 2016

New osseointegrated press-fit implant reduces infection risk for above knee amputees

A new study in today's issue of the Journal of Bone and Joint Surgery found minimal risk for severe infection with osseointegrated implants--a newer prosthetic system, press-fitted directly into the femur bone--that enables bone growth over a metal, robotic prosthetic limb in patients with above knee amputations.

2 Jun 2016

Mediodorsal thalamus plays key role in new learning and decision making

Scientists have confirmed one of the brain areas responsible for rapid updating of information during learning - the sort of information we use to negotiate many changing situations in everyday life.

1 Jun 2016

Readmission rates after major cancer procedures depend on patient cohort, hospital characteristics

Readmission rates after complex cancer operations tend to be higher in hospitals that are considered to be vulnerable because they serve as safety nets in their communities or have a high number of Medicaid patients.

1 Jun 2016

Denosumab drug that inhibits RANKL gene can prevent genetic breast cancer

An international team led by researchers at the Austrian Institute of Molecular Biotechnology in Vienna and the University of Maryland School of Medicine in Baltimore discovered that genetically determined breast cancer can be largely prevented by blocking a bone gene. An already approved drug could be quickly available and would then be the first breast cancer prevention drug.

1 Jun 2016

UA researcher aims to identify imaging biomarkers for effective screening of ovarian cancer

University of Arizona researcher Jennifer Barton is leading a two-year, $1 million project funded by the National Cancer Institute to identify imaging biomarkers of ovarian cancer, the most deadly gynecological cancer in the United States.

1 Jun 2016

Surgery News and Research

Novel treatment combination helps combat hard-to-treat pediatric neuroblastoma

New research reveals advances that could change gynecologic cancer standard-of-care treatments

Mastectomy followed by standard therapy improves survival in stage IV breast cancer patients

Earlier surgery may be better for early-onset Type 2 diabetes

Mortality risk proportional to PPM severity in aortic value surgery

Clinical study finds two topical skin creams as effective noninvasive treatments for low-risk superficial BCC

Scientists use new technique to repair fibrotic liver cells within the organ

Immunotherapy with experimental monoclonal antibody could reduce neuroblastoma tumors

Common genetic variant in HO-1 gene linked to AKI risk following cardiac surgery

Retroviral replicating vector can extend lives of brain cancer patients

Some women with ovarian cancer do not receive beneficial surgical treatment, study finds

Severe obesity may contribute to infection risk after bypass surgery

Scientists reveal how ER+ breast cancer uses cholesterol-based molecule to evade anti-hormone treatments

RSI-MRI imaging technology can effectively differentiate aggressive prostate cancer

Deployed military soldiers three times more likely to suffer non-combat musculoskeletal injuries

New osseointegrated press-fit implant reduces infection risk for above knee amputees

Mediodorsal thalamus plays key role in new learning and decision making

Readmission rates after major cancer procedures depend on patient cohort, hospital characteristics

Denosumab drug that inhibits RANKL gene can prevent genetic breast cancer

UA researcher aims to identify imaging biomarkers for effective screening of ovarian cancer

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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