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GEMINI LTS study: Patients with active ulcerative colitis report clinical improvements with vedolizumab treatment

Takeda Pharmaceutical Company Limited, (“Takeda”) today announced that the interim findings from the GEMINI Long-Term Safety (LTS) study were presented during the 2016 European Crohn's and Colitis Organisation (ECCO) Annual Scientific Meeting in Amsterdam, The Netherlands.

22 Mar 2016

Tews Laboratory uses LaVision BioTec UltraMicroscope to study molecular mechanisms of tumor invasion

LaVision BioTec, developers of advanced microscopy solutions for the life sciences, report on the work in the Tews Laboratory which is studying the molecular mechanisms of tumor invasion using an UltraMicroscope for enhanced imaging of cells.

22 Mar 2016

TGen scientists highlight advantages of using RNA-sequencing in precision medicine

Uncovering the genetic makeup of patients using DNA sequencing has in recent years provided physicians and their patients with a greater understanding of how best to diagnose and treat the diseases that plague humanity. This is the essence of precision medicine.

22 Mar 2016

UGA investigators find viable treatment for prostate cancer

Researchers at the University of Georgia have created a new therapeutic for prostate cancer that has shown great efficacy in mouse models of the disease. They published their findings recently in the journal Nanomedicine: Nanotechnology, Biology and Medicine.

22 Mar 2016

Cell biologists identify new way for curing cancer and vessel diseases

Cell biologists from the Lomonosov Moscow State University discovered a new way of regulating of cell motility -- this discovery will make possible development of new drugs for curing onco- and vessel diseases.

22 Mar 2016

Doctors now have better tool to assess individual kidney function

Doctors now have a much-improved tool to assess individual kidney function, thanks to the work of an international team led by University of Saskatchewan medical imaging specialists Drs. Carl and Michal Wesolowski.

21 Mar 2016

Mutated gene GT198 has strong potential in early diagnosis of breast cancer

When mutated, a gene known for its ability to repair DNA, appears to instead cause breast cancer, scientists report.

21 Mar 2016

Six1 gene may have more substantial role in human kidney development

The best laid plans of mice and men are a bit different -- at least when it comes to kidney development. Compared to a mouse, a human has nearly 100 times more nephrons, the functional units of the kidneys. Humans may owe these abundant nephrons to a gene called SIX1, according to a new paper published in the journal Development.

21 Mar 2016

Neutralizing acidic tumor environment increases efficacy of immune-targeting cancer therapies

Cancer cells have the ability to grow in an acidic tumor environment that is detrimental to other cells, including immune cells. In a Cancer Research cover article published this week, Moffitt Cancer Center reported that neutralizing the acidic tumor environment increases the efficacy of several immune-targeting cancer therapies.

19 Mar 2016

Genomic profiling could help provide targeted therapies for difficult to treat cancer tumors

Research from Rutgers Cancer Institute of New Jersey examining difficult to treat cancer tumors through genomic profiling shows that tumors with alterations in a signaling pathway responsible for cell regulation may respond to targeted therapy regardless of where the tumor originated in the body.

18 Mar 2016

Study sheds light on role of RNA editing in cancer

A new study provides insight on the potential role played by RNA (ribonucleic acid) editing in cancer. The findings, which appear online in the journal Scientific Reports, may further our understanding of an emerging mechanism implicated in tumor initiation and progression, and may thus lead to the development of better treatment options in the future.

18 Mar 2016

Neo-Bioscore staging system adds HER2 status for precise prognostic stratification of breast cancer subtypes

A new breast cancer staging system developed by researchers at The University of Texas MD Anderson Cancer Center finds that incorporating tumor biology is a critical prognostic indicator for women who undergo neoadjuvant, or pre-surgical, therapy for breast cancer.

18 Mar 2016

Inhibiting cholesterol esterification can potentiate antitumor activity of killer T cells

As key players in the immune system, T cells provide tumor surveillance and have direct antitumor effects. However, tumors can escape T-cell attack through various mechanisms in the tumor microenvironment. Reactivating the antitumor effects of T cells has shown great clinical benefits in treating various cancers.

18 Mar 2016

Molecular basis for tongue cancer progression: an interview with Dr Simona Principe

Head and neck cancers (HNC) are the sixth most common cancers worldwide, with approximately 600,000 new cases diagnosed every year.

From Beckman Coulter Life Sciences - Centrifugation 17 Mar 2016

New study reveals why certain cancer drugs not always effective in halting tumor growth

New cancer drugs allow doctors to tailor treatment based on the genetic profile of a patient's tumor. However, these drugs don't work at all in some patients, and they lose their effectiveness in others.

17 Mar 2016

Johns Hopkins scientists develop antibody to curb lung tumor cell growth, breast cancer metastasis

Johns Hopkins scientists report they have developed an antibody against a specific cellular gateway that suppresses lung tumor cell growth and breast cancer metastasis in transplanted tumor experiments in mice, according to a new study published in the February issue of Nature Communications.

17 Mar 2016

Halozyme Therapeutics doses first patient in Halo-301 | Pancreatic study

Halozyme Therapeutics, Inc., a biotechnology company developing novel oncology and drug-delivery therapies, today announced the first patient has been dosed in its Halo-301 | Pancreatic study, a Phase 3 clinical trial in previously untreated metastatic pancreatic cancer patients.

16 Mar 2016

Cell-based tests reveal no activity in cells exposed to vapour from Vype ePen

A series of cell-based tests developed to compare the biological impact of cigarette smoke with e-cigarette vapour revealed no activity in cells exposed to vapour from Vype ePen, a commercially available e-cigarette.

16 Mar 2016

Blocking Mena protein could help prevent cancer metastasis, says MIT researcher

A new study from MIT reveals how cancer cells take some of their first steps away from their original tumor sites. This spread, known as metastasis, is responsible for 90 percent of cancer deaths.

16 Mar 2016

ROBO1 protein may delay progression of breast cancer

A protein called ROBO1 may delay the progression of breast cancer, according to a paper published in The Journal of Cell Biology. The study, "Loss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK in response to stiffness" by Lily Thao-Nhi Le and colleagues, identifies a signaling pathway that may protect breast cells from the tumorigenic effects of stiff extracellular matrices.

16 Mar 2016

Tumor News and Research

GEMINI LTS study: Patients with active ulcerative colitis report clinical improvements with vedolizumab treatment

Tews Laboratory uses LaVision BioTec UltraMicroscope to study molecular mechanisms of tumor invasion

TGen scientists highlight advantages of using RNA-sequencing in precision medicine

UGA investigators find viable treatment for prostate cancer

Cell biologists identify new way for curing cancer and vessel diseases

Doctors now have better tool to assess individual kidney function

Mutated gene GT198 has strong potential in early diagnosis of breast cancer

Six1 gene may have more substantial role in human kidney development

Neutralizing acidic tumor environment increases efficacy of immune-targeting cancer therapies

Genomic profiling could help provide targeted therapies for difficult to treat cancer tumors

Study sheds light on role of RNA editing in cancer

Neo-Bioscore staging system adds HER2 status for precise prognostic stratification of breast cancer subtypes

Inhibiting cholesterol esterification can potentiate antitumor activity of killer T cells

Molecular basis for tongue cancer progression: an interview with Dr Simona Principe

New study reveals why certain cancer drugs not always effective in halting tumor growth

Johns Hopkins scientists develop antibody to curb lung tumor cell growth, breast cancer metastasis

Halozyme Therapeutics doses first patient in Halo-301 | Pancreatic study

Cell-based tests reveal no activity in cells exposed to vapour from Vype ePen

Blocking Mena protein could help prevent cancer metastasis, says MIT researcher

ROBO1 protein may delay progression of breast cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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