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UNC-45A protein plays critical role in breast cancer cell division and migration

Researchers have found that a protein linked to cell division and migration and tied to increased cell proliferation in ovarian tumors is also present at high levels in breast cancer specimens and cell lines. The protein, dubbed "UNC-45A," was also determined to be more active in breast cancer cells than in normal breast cells.

16 Sep 2011

New nanopore sensor can lead to early detection of lung cancer

When lung cancer strikes, it often spreads silently into more advanced stages before being detected. In a new article published in Nature Nanotechnology, biological engineers and medical scientists at the University of Missouri reveal how their discovery could provide a much earlier warning signal.

16 Sep 2011

Scientists uncover unknown fail-safe pathway for inherited disorders

Scientists at the University of California, San Diego School of Medicine have uncovered a previously unknown fail-safe (compensatory) pathway that potentially protects the brain and other organs from genetic and environmental threats.

16 Sep 2011

Anavex Life Sciences to present data on lead compound for Alzheimer’s at Japan Neuroscience Society

Anavex Life Sciences Corp. will present the most recent data showing the therapeutic potential of ANAVEX compounds in animal models of Alzheimer’s disease at a special symposium of the 34th annual meeting of the Japan Neuroscience Society. The symposium is being held in Yokohama, Japan from September 15-17, 2011.

15 Sep 2011

Demand for kidney transplant and dialysis increases due to diabetes prevalence

A survey reveals that the need for kidney transplants and dialysis is expected to soar by 2020 mainly due to a rise in diabetics developing chronic kidney disease and needing treatment. The total number of Australians being treated for end-stage kidney disease is forecast to rise by up to 80 per cent to about 4300 in the coming decade. While the fact that Australia's population is ageing and growing means more people are likely to develop end-stage kidney disease, the number of diabetics with the condition is also on the rise.

15 Sep 2011

Hengrui, Shanghai ChemPartner enter strategic development partnership for monoclonal antibodies

ShangPharma Corporation, a leading China-based pharmaceutical and biotechnology research and development outsourcing company, and Jiangsu Hengrui Medicine Co., Ltd., a leading Chinese pharmaceutical company, today announced that Shanghai ChemPartner, a wholly owned subsidiary of ShangPharma, and Hengrui have entered into a strategic partnership for the development of novel therapeutic monoclonal antibodies.

15 Sep 2011

New computational method quickly predicts three-dimensional structure of protein

An Oak Ridge National Laboratory invention able to quickly predict three-dimensional structure of protein could have huge implications for drug discovery and human health.

15 Sep 2011

Consensus panel calls for specialized nutrition therapy to manage obesity

A newly published consensus report prepared by a panel of clinical experts, with sponsorship from Nestle Health Science, reveals that there are opportunities to do more to manage the impact of obesity on the delivery of critical care, particularly in the area of nutrition therapy.

15 Sep 2011

Heart specialists reveal how pacemaker works at the biological level

Heart specialists at Johns Hopkins have figured out how a widely used pacemaker for heart failure, which makes both sides of the heart beat together to pump effectively, works at the biological level.

15 Sep 2011

Rac1 protein triggers growth of long 'legs' that could propel melanoma cells to spread

Cancer Research UK scientists have discovered that a protein called Rac1 prompts pigment cells to sprout long 'legs' that could propel skin cancer cells, allowing them to spread, according to research published in Developmental Cell today.

15 Sep 2011

First effective blood-stage vaccine against malaria

Scientists have identified the first effective blood-stage malaria vaccine, according to a New England Journal of Medicine study from University of Maryland School of Medicine researchers, in collaboration with the University of Bamako in Mali, West Africa, and other partners.

15 Sep 2011

Researchers discover several chemical compounds against human prion diseases

In a new study NYU School of Medicine researchers report that they have found several chemical compounds, including an antidepressant, that have powerful effects against brain-destroying prion infections in mice, opening the door to potential treatments for human prion diseases.

15 Sep 2011

Teen milk drinkers less likely to suffer from Type 2 diabetes

Developing healthy habits like drinking milk as a teen could have a long-term effect on a woman's risk for type 2 diabetes, according to new research in this month's issue of the American Journal of Clinical Nutrition.

14 Sep 2011

DiscoveryBioMed receives NIDDK grant for Cystic Fibrosis Corrector Ligand Drug Discovery program

DiscoveryBioMed, Inc. (DBM), a human cell-based drug discovery company, learned recently that its Cystic Fibrosis Corrector Ligand (CFCL) Drug Discovery program will be funded by the NIH. The two-year award will focus on validation and prioritization of several lead CFCL chemical classes, drugs that correct the most common cystic fibrosis (CF) disease-causing mutation.

14 Sep 2011

Lucentis receives Health Canada approval to treat vision loss from DME

Health Canada has approved Lucentis (ranibizumab) as a treatment for vision loss resulting from diabetic macular edema, one of the major causes of adult vision loss and an important complication of the growing epidemic of diabetes.

14 Sep 2011

Celecoxib inhibits GSK3 enzyme in lung cancer cells

Several clinical studies have shown that taking the anti-inflammatory drug celecoxib can reduce the risk of developing polyps that lead to colon cancers, at the cost of increasing the risk of heart disease. But what if this tradeoff was not necessary?

14 Sep 2011

Researchers evaluate effect of Terahertz radiation on gene expression in stem cells

Terahertz technologies show promise for myriad medical, military, security, and research applications ranging from the detection of cancer to airport security systems to shipment inspection to spectroscopy. Relatively little is known, however, about the effect of THz radiation on biological systems.

14 Sep 2011

STED microscope reveals that F-actin pervades immunological synapse

Making use of a new "super resolution" microscope that provides sharp images at extremely small scales, scientists have achieved unprecedented views of the immune system in action.

14 Sep 2011

BVES protein may play a role in colon cancer progression

A protein critical in heart development may also play a part in colon cancer progression. Research led by investigators from Vanderbilt-Ingram Cancer Center and the Vanderbilt Eye Institute suggests that the protein BVES (blood vessel endocardial substance) - which also is key in regulating corneal cells - may be a therapeutic target for halting colon cancer metastasis.

14 Sep 2011

Scientists decode new mechanism that regulates cell polarity in epithelial tissues, neurons

In the course of examining the Drosophila tumor suppressor gene (Dlg), scientists at the Helmholtz Zentrum München have succeeded in decoding a new mechanism that regulates cell polarity in epithelial tissues or in neurons in the brain.

14 Sep 2011

G Protein News and Research

UNC-45A protein plays critical role in breast cancer cell division and migration

New nanopore sensor can lead to early detection of lung cancer

Scientists uncover unknown fail-safe pathway for inherited disorders

Anavex Life Sciences to present data on lead compound for Alzheimer’s at Japan Neuroscience Society

Demand for kidney transplant and dialysis increases due to diabetes prevalence

Hengrui, Shanghai ChemPartner enter strategic development partnership for monoclonal antibodies

New computational method quickly predicts three-dimensional structure of protein

Consensus panel calls for specialized nutrition therapy to manage obesity

Heart specialists reveal how pacemaker works at the biological level

Rac1 protein triggers growth of long 'legs' that could propel melanoma cells to spread

First effective blood-stage vaccine against malaria

Researchers discover several chemical compounds against human prion diseases

Teen milk drinkers less likely to suffer from Type 2 diabetes

DiscoveryBioMed receives NIDDK grant for Cystic Fibrosis Corrector Ligand Drug Discovery program

Lucentis receives Health Canada approval to treat vision loss from DME

Celecoxib inhibits GSK3 enzyme in lung cancer cells

Researchers evaluate effect of Terahertz radiation on gene expression in stem cells

STED microscope reveals that F-actin pervades immunological synapse

BVES protein may play a role in colon cancer progression

Scientists decode new mechanism that regulates cell polarity in epithelial tissues, neurons

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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