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New, minimally invasive biomarker-based strategy 90% successful in detecting esophageal cancer

In a small but rigorous pilot study, Johns Hopkins Medicine researchers have shown that a novel, minimally invasive biomarker-based strategy they developed was 90% successful in detecting esophageal squamous cell carcinoma (ESCC), the predominant subtype of esophageal cancer worldwide.

18 May 2022

Study identifies cancer biomarkers based on a type of genetic modification

Biomarkers are often used during the management of cancer to guide treatment decisions and predict patient outcomes. However, it is often difficult to identify appropriate biomarkers that can be consistently reproduced and are easily analyzed with limited patient specimens.

18 May 2022

Study explores lipid nanoparticles against SARS-CoV-2

Researchers assessed the efficiency of lipid nanoparticles against SARS-CoV-2.

18 May 2022

Triple BNT162b2 vaccination found to establish long-term T lymphocyte immunity among MDS and CLL patients

In a new study, researchers evaluated the BNT162b2 coronavirus disease 2019 mRNA vaccine (antigen)-specific immune response among myeloid dysplastic syndrome and chronic lymphocytic leukemia patients.

18 May 2022

Study explores neurologic complications in pediatric COVID-19 cases

Researchers evaluated neurologic complications in pediatric cases of COVID-19.

18 May 2022

Developing innovative approaches to combat urinary tract infections

The German government is providing about 2.4 million Euros for a new research group in infectious diseases at JMU Würzburg.

18 May 2022

Case report: human breast milk from vaccinated woman clears persistent SARS-CoV-2 infection

A new study published in the journal Viruses aimed to report the effects of plasma infusion and then breastmilk ingestion as a therapy for persistent SARS-CoV-2 infection in a patient with a common variable immunodeficiency (CVID) phenotype.

18 May 2022

Exosomes derived from γδ-T cells synergized with radiotherapy can control nasopharyngeal carcinoma

A research team at LKS Faculty of Medicine, The University of Hong Kong discovered that exosomes derived from γδ-T cells (γδ-T-Exos) synergised with radiotherapy can control nasopharyngeal carcinoma (NPC) by overcoming the radioresistance of NPC cancer stem cells (CSCs) and preserve their tumor-killing and T cell-promoting activities in the immunosuppressive NPC microenvironment.

18 May 2022

Discovery of a potent SARS-CoV-2 RBD specific human monoclonal antibody

A recent article posted to the bioRxiv* preprint server demonstrated structural underpinnings of the neutralization of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variants by 002-S21F2, an extensive SARS-CoV-2 neutralizing antibody.

18 May 2022

Researchers create artificial cell membrane that can be kept stable for over 50 days

In nature, the cell membrane has a unique function of protecting the internal from the external environment and communicating outside by sensing the external chemical or physical stimuli like the most precise biosensor for life.

18 May 2022

Study shows why COPD patients are more vulnerable to severe COVID-19

Researchers from the Centenary Institute and the University of Technology Sydney have published the first study showing why people with chronic obstructive pulmonary disease (COPD) are at higher risk of developing severe COVID-19.

18 May 2022

Compound found in Datura shows promise as antiviral agent against SARS-CoV-2

Researchers from Naval Medical University have been investigating anisodamine, used in traditional Chinese medicine, to inhibit SARS-CoV-2 infection in cellular models. The study is published in the journal Biochemical and Biophysical Research Communications.

17 May 2022

Molecular RNA profile of naked mole-rats reveals new insights on skin aging

A new research paper was published on the cover of Aging (Aging-US) Volume 14, Issue 9, entitled, "Single-cell transcriptomics reveals age-resistant maintenance of cell identities, stem cell compartments and differentiation trajectories in long-lived naked mole-rats skin."

17 May 2022

Camelid IFNs could play important role in combating emerging zoonotic pathogens

In a recent study published in the Developmental & Comparative Immunology journal, the discovery of a novel form of mammalian interferon-Beta (IFN-β) with four cysteine residues from the dromedary camel and the five remaining members of the mammalian suborder Tylopoda is described.

17 May 2022

3rd dose of COVID mRNA vaccine expands memory and capacity of immune system to combat Omicron

Researchers from the United States have now found that the immune recall induced by a two-dose primary series of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination after an initial natural infection highly improves the longevity of the antibodies as well as induces an enhanced breadth of protection across the SARS-CoV-2 variants.

17 May 2022

Experimental drug more effective than existing FDA-approved medications for ALS

New research on the experimental drug, NU-9, invented and developed by two Northwestern University scientists to treat ALS (amyotrophic lateral sclerosis), shows it is more effective than existing FDA-approved drugs for the disease.

17 May 2022

Study: Daily intake of Urolithin A improves muscle strength by 12% after four months

Age-associated muscle decline can start as early as 40 years old and there are currently no effective interventions to counteract it other than exercise.

17 May 2022

Sonic hedgehog plays key role in the repair strategy of large bone injuries

A USC Stem Cell study in NPJ Regenerative Medicine presents intriguing evidence that large bone injuries might trigger a repair strategy in adults that recapitulates elements of skeletal formation in utero. Key to this repair strategy is a gene with a fittingly heroic name: Sonic hedgehog.

17 May 2022

Researchers explore broad-based immunity against potentially pandemic-causing viruses

A new study focused on broad-spectrum immunity against viruses that harbor the potential for generating a pandemic involving humans, especially those with the potential for zoonotic spillover.

17 May 2022

Exposure to cold and warm temperatures causes changes in gene expression in various organs

Human beings, like most organisms, are constantly exposed to alternating colder or warmer temperatures.

17 May 2022

B Cell News and Research

New, minimally invasive biomarker-based strategy 90% successful in detecting esophageal cancer

Study identifies cancer biomarkers based on a type of genetic modification

Study explores lipid nanoparticles against SARS-CoV-2

Triple BNT162b2 vaccination found to establish long-term T lymphocyte immunity among MDS and CLL patients

Study explores neurologic complications in pediatric COVID-19 cases

Developing innovative approaches to combat urinary tract infections

Case report: human breast milk from vaccinated woman clears persistent SARS-CoV-2 infection

Exosomes derived from γδ-T cells synergized with radiotherapy can control nasopharyngeal carcinoma

Discovery of a potent SARS-CoV-2 RBD specific human monoclonal antibody

Researchers create artificial cell membrane that can be kept stable for over 50 days

Study shows why COPD patients are more vulnerable to severe COVID-19

Compound found in Datura shows promise as antiviral agent against SARS-CoV-2

Molecular RNA profile of naked mole-rats reveals new insights on skin aging

Camelid IFNs could play important role in combating emerging zoonotic pathogens

3rd dose of COVID mRNA vaccine expands memory and capacity of immune system to combat Omicron

Experimental drug more effective than existing FDA-approved medications for ALS

Study: Daily intake of Urolithin A improves muscle strength by 12% after four months

Sonic hedgehog plays key role in the repair strategy of large bone injuries

Researchers explore broad-based immunity against potentially pandemic-causing viruses

Exposure to cold and warm temperatures causes changes in gene expression in various organs

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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