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Scientist wins 2021 Pioneer in Basic Science Award for breakthrough research on the inner ear

When Andrew Griffith, MD, PhD, looks at the inner ear, he sees what he describes as "an engineering marvel."

28 Jan 2021

New results challenge the current understanding of medulloblastoma

Scientists at St. Jude Children's Research Hospital and their colleagues have published a detailed account of SJMB03, a clinical trial for pediatric patients with medulloblastoma.

28 Jan 2021

Genetic changes in tumors can help predict the efficacy of immunotherapy drugs

Researchers at the Francis Crick Institute, the UCL Cancer Institute, and the Cancer Research UK Lung Cancer Centre of Excellence have identified genetic changes in tumors which could be used to predict if immunotherapy drugs would be effective in individual patients.

28 Jan 2021

Insight into cancer cells' own first aid could provide the basis for new immunotherapy

Insight into cancer cells' own first aid could help the development of a new type of treatment. Johanna Olweus and her team at the UiO (University of Oslo) and the OUS (Oslo University Hospital) are important contributors to this study, which has been published in Nature.

27 Jan 2021

New York Tech researchers receive NIH grant to improve the understanding of atherosclerosis

A New York Institute of Technology research team led by Olga V. Savinova, Ph.D., assistant professor of biomedical sciences at New York Institute of Technology College of Osteopathic Medicine, has secured a five-year grant from the National Institutes of Health National Heart, Lung, and Blood Institute.

27 Jan 2021

Study uncovers a novel promising target for diabetes treatment

Researchers have discovered a novel and druggable insulin inhibitory receptor, named inceptor. The latest study from Helmholtz Zentrum Muenchen, the Technical University of Munich and the German Center for Diabetes Research is a significant milestone for diabetes research as the scientific community celebrates 100 years of insulin and 50 years of insulin receptor discovery.

27 Jan 2021

If I have cancer, dementia or MS, should i get the covid vaccine?

As public demand grows for limited supplies of covid-19 vaccines, questions remain about the vaccines' appropriateness for older adults with various illnesses.

27 Jan 2021

Hybrid closed-loop insulin therapy improves glycemic control in adolescents, young adults

Hybrid closed-loop insulin therapy improved glycemic control in adolescents and young adults with type 1 diabetes. These outcomes, derived from the International Diabetes Closed-Loop (iDCL) Trial, are reported in the peer-reviewed journal Diabetes Technology & Therapeutics (DTT).

27 Jan 2021

Medicinal cannabis improves outcomes in Parkinson's patients

With medicinal cannabis now legalized in many parts of the world, there is growing interest in its use to alleviate symptoms of many illnesses including Parkinson's disease (PD).

27 Jan 2021

Novel immunotherapy combination can be highly effective for treating lung cancer

McMaster University researchers have established in lab settings that a novel combination of two forms of immunotherapy can be highly effective for treating lung cancer, which causes more deaths than any other form of cancer.

27 Jan 2021

Two-drug combination approach could be effective against bone cancer

An innovative approach to treating bone tumors - starving cancer cells of the energy they need to grow - could one day provide an alternative to a commonly used chemotherapy drug without the risk of severe side effects, suggests a new study from Washington University School of Medicine in St. Louis.

27 Jan 2021

Study shows how gut bacteria can dull the efficacy of radiotherapy

A study led by Ludwig Chicago Co-director Ralph Weichselbaum and Yang-Xin Fu of the University of Texas Southwestern Medical Center has shown how bacteria in the gut can dull the efficacy of radiotherapy, a treatment received by about half of all cancer patients.

26 Jan 2021

Study uses computational framework to identify tamoxifen resistance markers in ER+ breast cancer

One common challenge of cancer therapy is when cancer cells don't respond to a drug that is usually able to kill or weaken them, known as treatment resistance.

26 Jan 2021

Anti-emetic drug offers a promising approach to treat chronic myeloid leukemia

Chronic myeloid leukemia (CML) results from a degeneration of the hematopoietic stem cells (leukemia stem cells), thereby leading to the uncontrolled formation of specific white blood cells, the so-called granulocytes.

26 Jan 2021

£1.6 million grant awarded to advance development of MND drug candidate

Researchers from the University of Sheffield's Institute for Translational Neuroscience have been awarded a £1.6 million grant from the Medical Research Council.

26 Jan 2021

Prostate cancer: Drug-resistant, metastasis-causing cells can produce exponentially growing tumors

The cover for issue 1 of Oncotarget features Figure 2, "Results in clinical trials," published in "Drug resistant cells with very large proliferative potential grow exponentially in metastatic prostate cancer" by Blagoev, et al. which reported that most metastatic cancers develop drug resistance during treatment and continue to grow, driven by a subpopulation of cancer cells unresponsive to the therapy being administered.

26 Jan 2021

Astrocytes might be a potential new target to better treat epilepsy

A significant number of epilepsy patients does not respond to currently available drugs. A collaboration between researchers in Japan and at the Heinrich Heine University Düsseldorf now addressed a cell type in the brain that has so far not received much attention in epilepsy therapy.

26 Jan 2021

Researchers engineer antibody that broadly neutralizes a range of clade 1 sarbecoviruses

Researchers have engineered an antibody that neutralizes SARS-CoV-2 with a potency that "rivals" current lead SARS-CoV-2 clinical neutralizing antibodies, and that also broadly neutralizes a range of clade 1 sarbecoviruses.

26 Jan 2021

Five-day regimen of radiotherapy safe, effective for men with high-risk forms of prostate cancer

A study led by researchers at the UCLA Jonsson Comprehensive Cancer Center found shortening a traditional 45-day course of radiation to a five-day course delivered in larger doses is safe and as effective as conventional radiation for men with high-risk forms of prostate cancer.

26 Jan 2021

Drug intervention may prevent heart damage caused by chemotherapy

There could be an intervention on the horizon to help prevent heart damage caused by the common chemotherapy drug doxorubicin, new research suggests.

26 Jan 2021

Therapy News and Research

Scientist wins 2021 Pioneer in Basic Science Award for breakthrough research on the inner ear

New results challenge the current understanding of medulloblastoma

Genetic changes in tumors can help predict the efficacy of immunotherapy drugs

Insight into cancer cells' own first aid could provide the basis for new immunotherapy

New York Tech researchers receive NIH grant to improve the understanding of atherosclerosis

Study uncovers a novel promising target for diabetes treatment

If I have cancer, dementia or MS, should i get the covid vaccine?

Hybrid closed-loop insulin therapy improves glycemic control in adolescents, young adults

Medicinal cannabis improves outcomes in Parkinson's patients

Novel immunotherapy combination can be highly effective for treating lung cancer

Two-drug combination approach could be effective against bone cancer

Study shows how gut bacteria can dull the efficacy of radiotherapy

Study uses computational framework to identify tamoxifen resistance markers in ER+ breast cancer

Anti-emetic drug offers a promising approach to treat chronic myeloid leukemia

£1.6 million grant awarded to advance development of MND drug candidate

Prostate cancer: Drug-resistant, metastasis-causing cells can produce exponentially growing tumors

Astrocytes might be a potential new target to better treat epilepsy

Researchers engineer antibody that broadly neutralizes a range of clade 1 sarbecoviruses

Five-day regimen of radiotherapy safe, effective for men with high-risk forms of prostate cancer

Drug intervention may prevent heart damage caused by chemotherapy

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