Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Results from Morphotek’s farletuzumab Phase III combination study on ovarian cancer

Morphotek Inc., a wholly-owned subsidiary of Eisai Inc., announced today top-line results from a Phase III study of its investigational agent farletuzumab (MORAb-003) in combination with carboplatin and a taxane in patients with platinum-sensitive epithelial ovarian cancer in first relapse.

11 Jan 2013

New guidelines to help fast track radiation oncology drug development

Researchers from the translational research program of the National Cancer Institute and the Radiation Therapy Oncology Therapy Group have developed new guidelines to help fast track the clinical development of targeted cancer drugs in combination with radiation therapy.

11 Jan 2013

Research: Smaller radiation fields can effectively treat aggressive brain tumors

New research from Wake Forest Baptist Medical Center shows that patients suffering from aggressive brain tumors can be effectively treated with smaller radiation fields to spare the rest of the brain and preserve cognition.

11 Jan 2013

Johns Hopkins develops PapGene test to diagnose ovarian and endometrial cancers

Using cervical fluid obtained during routine Pap tests, scientists at the Johns Hopkins Kimmel Cancer Center have developed a test to detect ovarian and endometrial cancers. In a pilot study, the "PapGene" test, which relies on genomic sequencing of cancer-specific mutations, accurately detected all 24 (100 percent) endometrial cancers and nine of 22 (41 percent) ovarian cancers. Results of the experiments are published in the Jan. 9 issue of the journal Science Translational Medicine.

11 Jan 2013

TapImmune announces results from HER2/neu interim study on breast cancer

TapImmune Inc. has announced that an interim safety analysis on the first five breast cancer patients treated with HER2/neu Class II antigens at Mayo Clinic, Rochester, MN., did not show any serious adverse events.

11 Jan 2013

UCSF Helen Diller Family Comprehensive Cancer Center receives $36M NCI grant

The National Cancer Institute has awarded the UCSF Helen Diller Family Comprehensive Cancer Center a $36 million grant to fund cutting edge research programs and clinical trials over five years.

10 Jan 2013

Fingolimod could potentially eliminate or reduce progression of colitis-associated cancer

After uncovering a mechanism that promotes chronic intestinal inflammation and the development of colorectal cancer, scientists from Virginia Commonwealth University Massey Cancer Center have found that fingolimod, a drug currently approved for the treatment of multiple sclerosis, could potentially eliminate or reduce the progression of colitis-associated cancer (CAC).

10 Jan 2013

Tibial artery calcification predicts foot ulceration

Tibial artery calcification is a significant risk factor for foot ulcers in patients with Type 2 diabetes, research suggests.

9 Jan 2013

Moffitt Cancer Center initiates PV-10 Phase 1 study in melanoma

Provectus Pharmaceuticals, Inc., a development-stage oncology and dermatology biopharmaceutical company, reports that the Moffitt Cancer Center has initiated a Phase 1 study to investigate potential immune biomarkers in both tumor tissue and peripheral blood after intralesional PV-10 injection of melanoma tumors.

9 Jan 2013

CTI initiates enrollment in pacritinib Phase 3 trial for myelofibrosis

Cell Therapeutics, Inc. (CTI) today announced that the Company has initiated clinical trial sites and began enrolling patients in a Phase 3 clinical trial, known as PERSIST-1 or PAC325, for pacritinib, CTI's investigational JAK2 inhibitor, which is being evaluated for the treatment of patients with myelofibrosis.

9 Jan 2013

Combination of pazopanib and paclitaxel shows promise in slowing anaplastic thyroid cancer

A combination of the drugs pazopanib and paclitaxel shows promise in slowing anaplastic thyroid cancer (ATC), according to a Mayo Clinic-led study published in the journal Science Translational Medicine.

9 Jan 2013

Education for dementia staff may need improvement

Staff who work with dementia patients should receive education about the condition as a mandatory component of both employment criteria and staff development programs, say Australian researchers.

8 Jan 2013

Spectrum Pharmaceuticals reveals positive RenaZorb Phase 1 clinical trial results

Spectrum Pharmaceuticals, a biotechnology company with fully integrated commercial and drug development operations with a primary focus in hematology and oncology, today announced positive, statistically significant data from the Company's Phase 1 clinical trial evaluating the safety and tolerability of RenaZorb (also referred to as SPI-014) in healthy volunteers.

8 Jan 2013

Link between Parkinson's and benomyl

For several years, neurologists at UCLA have been building a case that a link exists between pesticides and Parkinson's disease. To date, paraquat, maneb and ziram - common chemicals sprayed in California's Central Valley and elsewhere - have been tied to increases in the disease, not only among farmworkers but in individuals who simply lived or worked near fields and likely inhaled drifting particles.

6 Jan 2013

Scientists discover process by which mda-9/syntenin contributes to melanoma metastasis

After recently announcing success in eliminating melanoma metastasis in laboratory experiments, scientists at Virginia Commonwealth University Massey Cancer Center have made another important discovery in understanding the process by which the gene mda-9/syntenin contributes to metastasis in melanoma (the spread of skin cancer) and possibly a variety of other cancers.

4 Jan 2013

MRI could serve as lumbar puncture proxy

Structural brain patterns on magnetic resonance imaging predict cerebrospinal fluid biomarker levels in patients with suspected Alzheimer’s disease or frontotemporal lobar degeneration, preliminary research suggests.

3 Jan 2013

$Bayer, Onyx announce data from Nexavar Phase 3 trial on RAI-refractory differentiated thyroid cancer$

Bayer, Onyx announce data from Nexavar Phase 3 trial on RAI-refractory differentiated thyroid cancer

Bayer HealthCare Pharmaceuticals and Onyx Pharmaceuticals, Inc. today announced that a Phase 3 trial of Nexavar (sorafenib) tablets in patients with locally advanced or metastatic radioactive iodine-refractory (RAI) differentiated thyroid cancer has met its primary endpoint of a statistically significant improvement of progression-free survival.

3 Jan 2013

18F-FDG PET/CT may become important distant staging modality in patients with breast cancer

New research published in the January issue of The Journal of Nuclear Medicine shows that 18F-fludeoxyglucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) imaging offers significant prognostic stratification information at initial staging for patients with locally advanced breast cancer. When compared to conventional imaging, 18F-FDG PET/CT more accurately showed lesions in the chest, abdomen and bones in a single session, changing management for more than 50 percent of the patients in the study.

3 Jan 2013

Glaucoma likely to end in visual impairment

Visual impairment at the end of life is highly likely to occur in patients with glaucoma, show Dutch study results.

2 Jan 2013

Thromboprophylaxis does more harm than good in head and neck surgery

Patients undergoing oncologic head and neck surgery do not benefit from thromboprophylaxis, report researchers.

2 Jan 2013

Oncology News and Research

Further Reading

Results from Morphotek’s farletuzumab Phase III combination study on ovarian cancer

New guidelines to help fast track radiation oncology drug development

Research: Smaller radiation fields can effectively treat aggressive brain tumors

Johns Hopkins develops PapGene test to diagnose ovarian and endometrial cancers

TapImmune announces results from HER2/neu interim study on breast cancer

UCSF Helen Diller Family Comprehensive Cancer Center receives $36M NCI grant

Fingolimod could potentially eliminate or reduce progression of colitis-associated cancer

Tibial artery calcification predicts foot ulceration

Moffitt Cancer Center initiates PV-10 Phase 1 study in melanoma

CTI initiates enrollment in pacritinib Phase 3 trial for myelofibrosis

Combination of pazopanib and paclitaxel shows promise in slowing anaplastic thyroid cancer

Education for dementia staff may need improvement

Spectrum Pharmaceuticals reveals positive RenaZorb Phase 1 clinical trial results

Link between Parkinson's and benomyl

Scientists discover process by which mda-9/syntenin contributes to melanoma metastasis

MRI could serve as lumbar puncture proxy

Bayer, Onyx announce data from Nexavar Phase 3 trial on RAI-refractory differentiated thyroid cancer

18F-FDG PET/CT may become important distant staging modality in patients with breast cancer

Glaucoma likely to end in visual impairment

Thromboprophylaxis does more harm than good in head and neck surgery

eBook: Liquid biopsy in cancer research eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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