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New pain management regimen reduced opioid exposure in trauma patients

A pain management regimen comprised mostly of over-the-counter medication reduced opioid exposure in trauma patients while achieving equal levels of pain control, according to a new study by physician-researchers at The University of Texas Health Science Center at Houston (UTHealth).

22 Jan 2021

New study helps understand molecular profile of tumors in cancer patients

Researchers from the University Hospitals in Zurich and Basel, ETH Zurich, University of Zurich and the pharmaceutical company Roche have set out to improve cancer diagnostics by developing a platform of state-of-the-art molecular biology methods.

21 Jan 2021

New model shows key role of innate immunity in controlling COVID-19 viral load

Since SARS-CoV-2 was identified in December 2019, researchers have worked feverishly to study the novel coronavirus. Although much knowledge has been gained, scientists still have a lot to learn about how SARS-CoV-2 interacts with the human body, and how the immune system fights it.

21 Jan 2021

Dynamic, customized treatment approaches for gastroesophageal cancers may improve survival rates

A phase 2 clinical trial providing personalized treatments based on the genetic profile of metastatic tumors in gastroesophageal cancers has found that using customized treatment approaches, and adapting them over time as tumors become resistant, led to higher rates of survival compared to historical controls.

21 Jan 2021

SARS-CoV-2 suppresses host innate immunity

SARS-CoV-2, the virus that causes COVID-19, blocks the processes of innate immune activation that normally direct the production and/or signaling of type I interferon (IFN-I) by the infected cell and tissues.

21 Jan 2021

Investigational combo therapy shows promise in treating TP53 mutant MDS and AML patients

Myelodysplastic Syndromes (MDS) and acute myeloid leukemia (AML) are rare hematologic malignancies of the bone marrow.

21 Jan 2021

Toward patient-derived models to help personalize cancer care

Cancer is a major, worldwide challenge, and its impact is projected to escalate due to aging and growth of the population.

21 Jan 2021

Using gene therapy to mimic the effects of physical exercise

It sounds too good to be true - and it is. But Jose Bianco Moreira and the CERG research group at the Norwegian University of Science and Technology are convinced that some of the positive health effects of physical exercise can be achieved using gene therapy and medication.

21 Jan 2021

Vitamin D deficiency associated with higher risk of COVID-19 hospitalization

A new study published shows that low levels of vitamin D are associated with a higher risk of COVID-19 hospitalization.

21 Jan 2021

Blood group associated with cardiovascular events in COVID-19 patients

An illuminating new study by scientists at Harvard Medical School, USA, describes the correlation of such conditions with the ABO blood group. The team's findings may help assess the risk of COVID-19 patients for such complications, promoting early diagnosis and underscoring potential needs for preventive and therapeutic care where possible.

21 Jan 2021

Can cancer patients receive urgent care without risk of COVID-19?

A new study describes how a successful application of mitigation techniques to prevent COVID-19 transmission to cancer patients admitted to or attending a healthcare facility might look.

21 Jan 2021

PromoCell's New GMP Certification - EXCiPACT

In this interview, News-Medical talks to Dr. Irma Börcsök (CEO of PromoCell) and Dörte Keimer (Head of Quality Assurance) about PromoCell, the work they do and the latest GMP certification the company has achieved - EXCiPACT.

From PromoCell 21 Jan 2021

Pharmacists play key role in managing medication-based therapies for older patients

Pharmacists play an important role in managing medication-based therapies for older community-dwelling patients, according to a study published in the British Journal of Clinical Pharmacology.

21 Jan 2021

Potentially promising therapeutic combination for renal cell carcinoma uncovered

Renal cell carcinoma (RCC) is the most common form of cancer of the kidney. In 2018, there were an estimated 403,000 new cases of RCC and 175,000 deaths due to kidney cancer worldwide.

20 Jan 2021

Hematopoietic stem cell transplants may prevent worsening of MS disability

A new study shows that intense immunosuppression followed by a hematopoietic stem cell transplant may prevent disability associated with multiple sclerosis (MS) from getting worse in 71% of people with relapsing-remitting MS for up to 10 years after the treatment.

20 Jan 2021

Designer DNA agent reduces myeloma stem cell abundance, lowers disease burden in mice

Many patients with multiple myeloma, a type of blood cancer, eventually develop resistance to one treatment after another. That's in part because cancer stem cells drive the disease -- cells that continually self-renew. If a therapy can't completely destroy these malignant stem cells, the cancer is likely to keep coming back.

20 Jan 2021

Analysis reveals rapid surge in methamphetamine overdose deaths in the United States

Methamphetamine overdose deaths surged in an eight-year period in the United States, according to a study published today in JAMA Psychiatry.

20 Jan 2021

Advocates view health care as key to driving LGBTQ rights conversation

When Allison Scott came out as a trans woman in 2013, she told not only family and friends, but also her primary care physician.

20 Jan 2021

Patients fend for themselves to access highly touted covid antibody treatments

By the time he tested positive for covid-19 on Jan. 12, Gary Herritz was feeling pretty sick. He suspects he was infected a week earlier, during a medical appointment in which he saw health workers who were wearing masks beneath their noses or who had removed them entirely.

20 Jan 2021

Gene editing shows potential to correct mutations causing inherited retinal degeneration

Gene editing therapies, including CRISPR-Cas systems, offer the potential to correct mutations causing inherited retinal degenerations, a leading cause of blindness.

20 Jan 2021

Therapy News and Research

New pain management regimen reduced opioid exposure in trauma patients

New study helps understand molecular profile of tumors in cancer patients

New model shows key role of innate immunity in controlling COVID-19 viral load

Dynamic, customized treatment approaches for gastroesophageal cancers may improve survival rates

SARS-CoV-2 suppresses host innate immunity

Investigational combo therapy shows promise in treating TP53 mutant MDS and AML patients

Toward patient-derived models to help personalize cancer care

Using gene therapy to mimic the effects of physical exercise

Vitamin D deficiency associated with higher risk of COVID-19 hospitalization

Blood group associated with cardiovascular events in COVID-19 patients

Can cancer patients receive urgent care without risk of COVID-19?

PromoCell's New GMP Certification - EXCiPACT

Pharmacists play key role in managing medication-based therapies for older patients

Potentially promising therapeutic combination for renal cell carcinoma uncovered

Hematopoietic stem cell transplants may prevent worsening of MS disability

Designer DNA agent reduces myeloma stem cell abundance, lowers disease burden in mice

Analysis reveals rapid surge in methamphetamine overdose deaths in the United States

Advocates view health care as key to driving LGBTQ rights conversation

Patients fend for themselves to access highly touted covid antibody treatments

Gene editing shows potential to correct mutations causing inherited retinal degeneration

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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