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Study provides evidence that adult planarians harbor pluripotent stem cells

A single adult cell from one of the most impressive masters of regeneration in the animal kingdom - the planarian - is all it takes to build a completely functional new worm, researchers have learned. The study provides the first hard evidence that adult planarians harbor pluripotent stem cells - cells capable of producing the diverse range of tissue types necessary to build a complete animal.

13 May 2011

$100,000 needed to analyze '$1,000' genetic data

Advances in technology have almost lifted the curtain on the long-awaited era of the "$1,000 genome" - a time when all the genes that make up a person can be deciphered for about that amount - compared to nearly $1 million a few years ago.

12 May 2011

New research sheds light on common pathogenic mechanisms underlying Huntington's disease

New research sheds light on common pathogenic mechanisms shared by Huntington's disease (HD) and HD-like disorders. The study, published by Cell Press in the May 12, 2011, issue of the journal Neuron, uses a new transgenic mouse model for an HD-like disorder to unravel complex molecular events that drive disease pathology.

12 May 2011

New genome-wide study identifies causes of serious childhood immune disorder

A new genomics study, led by the Center for Applied Genomics at The Children's Hospital of Philadelphia, sets the stage for the first predictive diagnostic test in a serious immunodeficiency disease in children. If the disorder, common variable immunodeficiency disease, can be diagnosed early, children may receive life-saving treatments before the disease can progress.

12 May 2011

GenoLogics enhances LIMS software for next-generation genomics labs

GenoLogics, a leading provider of laboratory information management system (LIMS) software for next-generation genomics labs, today announced a detailed product roadmap for its eponymous LIMS, designed to provide the scalability, adaptability and usability features necessary for mainstream adoption of the most advanced sequencing technologies while supporting existing genotyping platforms.

11 May 2011

16-year-old uses supercomputing network to invent new drug cocktail for cystic fibrosis

While many 16-year-olds are content with PlayStation, Toronto-area student Marshall Zhang used the Canadian SCINET supercomputing network to invent a new drug cocktail which could one day help treat cystic fibrosis.

11 May 2011

Researchers identify mitochondrial proteins that can affect human ageing

Mitochondria are the body's energy producers, the power stations inside our cells. Researchers at the University of Gothenburg, Sweden, have now identified a group of mitochondrial proteins, the absence of which allows other protein groups to stabilise the genome. This could delay the onset of age-related diseases and increase lifespan.

10 May 2011

Treatment with estrogen-lowering drugs shrinks tumors and reduces mastectomy rates in breast cancer patients

In the first large trial of its kind in the United States, researchers have shown that estrogen-lowering drugs can shrink tumors and reduce mastectomy rates for patients with stage 2 or 3 breast cancer.

10 May 2011

Researchers design new tool for identifying protein function from genetic code

Mayo Clinic researchers have designed a new tool for identifying protein function from genetic code. A team led by Stephen Ekker, Ph.D., succeeded in switching individual genes off and on in zebrafish, then observing embryonic and juvenile development.

10 May 2011

Scientists decipher genome of tropical marine organism

An international team of researchers led by scientists at Scripps Institution of Oceanography at UC San Diego has deciphered the genome of a tropical marine organism known to produce substances potentially useful against human diseases.

10 May 2011

Three Ontario projects set to further knowledge and discovery in biomonitoring, drug development

As part of the Genome Canada Large-Scale Applied Research Project Competition, which as a whole awarded over $58 million to 16 projects across the country, the researchers in Ontario will be focusing on biomonitoring, understanding gene function with the aim of identifying genes or proteins for drug targets, and the creation of synthetic antibodies to target cancers and other diseases.

9 May 2011

Illumina announces price reduction in whole human genome sequencing projects

Illumina, Inc. today announced that it is significantly reducing the price for sequencing whole human genomes through the Illumina Genome Network.

From Illumina, Inc. 9 May 2011

FDA clears Affymetrix's new gene profiling reagents for use in microarray instrument system

Affymetrix, Inc. today announced that the U.S. Food and Drug Administration has cleared the addition of new gene expression reagents as accessories to its GeneChip Microarray Instrument System for in vitro diagnostic use, making Affymetrix the first in the industry to provide a comprehensive microarray-based clinical toolkit for diagnostic test development, signature discovery for companion diagnostics, and translational initiatives. Affymetrix Gene Profiling Reagents offer unparalleled convenience by simplifying assay workflow, decreasing hands-on time, and reducing quality control testing compared to research-use-only-produced products.

9 May 2011

New international project to create more mutant genes, address shortage of Cre resources

Local scientists are now part of an International team compiling an enormous bank of resources for research into the functions of all known genes. The development of these biological resources will eventually allow scientists to know how the human genome behaves in health and disease.

9 May 2011

Researchers analyze gene expression profiles to understand molecular mechanisms behind various diseases

Over the past decades, researchers seeking to understand molecular mechanisms underlying various diseases, notably cancer, have taken advantage of DNA microarrays to interrogate tissues specimen of patients for the expression status of thousands of genes at once.

9 May 2011

UT Southwestern researcher measures estrogen's effect on breast cancer cells

A UT Southwestern Medical Center researcher has identified the most comprehensive measurement to date of estrogen's effect on breast cancer cells, showing for the first time how immediate and extensive the effect is.

6 May 2011

Scientists use new technologies to identify genetic cause of Kufs disease

Scientists from the Walter and Eliza Hall Institute and the University of Melbourne have used innovative new technologies to identify the gene responsible for a rare but fatal hereditary brain disorder. The discovery will make it possible to diagnose the disease through a blood test rather than a brain biopsy.

6 May 2011

Genome News and Research

Study provides evidence that adult planarians harbor pluripotent stem cells

$100,000 needed to analyze '$1,000' genetic data

New research sheds light on common pathogenic mechanisms underlying Huntington's disease

New genome-wide study identifies causes of serious childhood immune disorder

GenoLogics enhances LIMS software for next-generation genomics labs

16-year-old uses supercomputing network to invent new drug cocktail for cystic fibrosis

Researchers identify mitochondrial proteins that can affect human ageing

Treatment with estrogen-lowering drugs shrinks tumors and reduces mastectomy rates in breast cancer patients

Researchers design new tool for identifying protein function from genetic code

Scientists decipher genome of tropical marine organism

Three Ontario projects set to further knowledge and discovery in biomonitoring, drug development

Illumina announces price reduction in whole human genome sequencing projects

FDA clears Affymetrix's new gene profiling reagents for use in microarray instrument system

New international project to create more mutant genes, address shortage of Cre resources

Researchers analyze gene expression profiles to understand molecular mechanisms behind various diseases

UT Southwestern researcher measures estrogen's effect on breast cancer cells

Scientists use new technologies to identify genetic cause of Kufs disease

Scripps Research receives CIRM grant for new research in stem cell biology and disease origins

Genome epigenetic analysis reveals new ways to detect and treat breast cancer

BUSM research shows how heparan sulfate interacts with growth factor proteins

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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