Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Infectex initiates enrollment in SQ109 Phase IIb-III trial for MDR-TB

Infectex, a Russian biotech company in Maxwell Biotech Venture Fund's portfolio, announced today enrollment of the first patients in its Phase IIb-III clinical trial of SQ109 for MDR-TB. Infectex was founded in 2011 to develop and commercialize innovative products for the treatment of TB.

19 Dec 2012

EMD Serono's L-BLP25 Phase III NSCLC trial does not meet primary endpoint

EMD Serono, a subsidiary of Merck KGaA, Darmstadt, Germany, announced today that the Phase III STARTa trial of its investigational product L-BLP25 (formerly referred to as Stimuvax) in patients with unresectable, locally advanced stage IIIA or IIIB non-small cell lung cancer (NSCLC) did not meet its primary endpoint to demonstrate a statistically significant improvement in overall survival (OS).

19 Dec 2012

British Pharmacological Society celebrates the start of annual meeting

The British Pharmacological Society (BPS) today celebrated the start of its annual meeting, which will cover the latest research in drug discovery over the next three days, including a special focus on discoveries in cancer treatment.

19 Dec 2012

MiR-181 molecule tied to breast cancer metastasis

Researchers at Case Western Reserve University School of Medicine have identified a molecule linked to more aggressive forms of breast cancer - a discovery that could point the way to potential cures.

18 Dec 2012

e-Therapeutics’ ETS2101 cancer trials on track

e-Therapeutics plc today provides an update on the clinical trials of its cancer drug ETS2101. Two phase I studies, one in patients with primary or secondary brain cancer and the other in patients with various solid tumours, remain on track to report final data in Q4 2013 and Q1 2014, respectively. Interim data from the trials are expected in H1 2013.

18 Dec 2012

Klerokinesis may prevent some cancers from developing

Researchers at the University of Wisconsin Carbone Cancer Center have discovered a new form of cell division in human cells.

18 Dec 2012

Vero system can treat patients with recent diagnoses of metastatic cancer

University of Florida radiation oncologists are using a sophisticated medical device to treat patients who have recent diagnoses of metastatic cancer, where the disease has started to spread from one part of the body to another.

18 Dec 2012

Researchers identify possible heredity mechanism that predisposes children to ALL

Researchers at the Sainte-Justine University Hospital Center and the University of Montreal have found a possible heredity mechanism that predisposes children to acute lymphoblastic leukemia (ALL), the most common type of blood cancer in children. According to their findings published in Genome Research, the presence of a genetic defect in the egg or sperm from which children having ALL arise may be a prerequisite for the disease to develop.

17 Dec 2012

Cytokine rise signals RCC progression

Progression of renal cell carcinoma is frequently preceded by a rise in levels of proangiogenic cytokines, Italian researchers have found.

17 Dec 2012

Abiraterone improves outcomes for prostate cancer prior to chemo

Treatment with abiraterone acetate, an androgen biosynthesis inhibitor, may benefit patients with progressive metastatic castration-resistant prostate cancer who have not yet undergone chemotherapy, report researchers.

17 Dec 2012

Lapatinib benefits found for HER2-positive early-stage patients

Women with early-stage, HER2-positive breast cancer who are unable to use trastuzumab may benefit from adjuvant lapatinib treatment, suggest phase III trial findings published in Lancet Oncology.

17 Dec 2012

Improving environment can get elderly out and about

Simple changes in an older person’s local environment can have a positive impact on their level of outdoor physical activity, suggest study findings.

17 Dec 2012

Healthy behavior at middle age is critical to 'successful' aging

Observing a combination of healthy behaviors during middle age, including moderate exercise and alcohol intake, and not smoking, can significantly improve the chances of aging successfully, study findings show.

17 Dec 2012

Elekta receives clearance for Clarity 4D Monitoring software

Elekta has received 510(k) clearance for its Clarity 4D Monitoring software, enabling U.S. medical centers to implement this new way of reducing the uncertainty caused by prostate motion during radiation treatment.

From Elekta 17 Dec 2012

ProMining Therapeutics, Roche to develop small molecule therapeutics for type 2 diabetes mellitus

ProMining Therapeutics, Ltd. today announced a new collaboration with Roche in the field of type 2 diabetes mellitus.

17 Dec 2012

Range of epigenetic immunoassays from VolitionRx now available for research use

VolitionRx Limited, a life sciences company focused on developing blood-based diagnostic tests, announces the launch of NuQ, its range of research use only epigenetic immunoassays, to be available for sale at www.nucleosomics.com.

17 Dec 2012

Immunohistochemistry reliable in identifying ALK rearrangement: Study

Favorable results have led to crizotinib gaining approval for the treatment of advanced stage ALK-positive non-small cell lung cancer (NSCLC) in Japan, the United States, Canada, and several other countries in Europe and Asia.

17 Dec 2012

Strong unadjusted relationship between COPD, pneumonia and lung cancer

Chronic obstructive pulmonary disease (COPD) and lung cancer are two of the most important smoking-related diseases worldwide, with a huge combined mortality bur-den. Many consider the presence of COPD itself to be an independent risk factor for lung cancer. Others argue that smoking contributes to both COPD and lung cancer.

17 Dec 2012

American Thoracic Society, IASLC and ERS propose new sub-classification of lung adenocarcinomas

The International Association for the Study of Lung Cancer (IASLC), the American Thoracic Society (ATS), and the European Respiratory Society (ERS), have proposed a new sub-classification of lung adenocarcinomas.

16 Dec 2012

Multiple Myeloma Research Foundation, Bristol-Myers Squibb announce partnership

The Multiple Myeloma Research Foundation (MMRF) today announced that Bristol-Myers Squibb has joined the MMRF pre-competitive consortium (PCC) to discover and accelerate new approaches to treating multiple myeloma through the organization's Personalized Medicine Initiative (PMI).

15 Dec 2012