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OU College of Medicine, US Department of Defense to address problematic sexual behavior of youth

When young people act out sexually in ways that are harmful to others or themselves, the stigma surrounding the issue can be paralyzing for everyone affected.

19 Nov 2020

NIH project aims to maximize efficiency of AAV platform for gene therapy

Maximizing the efficiency of the adeno-associated virus (AAV) platform for gene therapy is the aim of a new pilot project of the National Institutes of Health (NIH).

19 Nov 2020

Immunotherapies effective against lung cancer, melanoma may also work against rare skin tumor

Cutaneous angiosarcoma is a rare, highly aggressive skin tumor found primarily on the scalps of older White people, but based on new research from the University of North Carolina School of Medicine and the Lineberger Comprehensive Cancer Center, immunotherapies effective against lung cancer and melanoma may also work against this cancer.

18 Nov 2020

New data highlights the gaps in care for children with familial hypercholesterolemia

Children born with a common genetic condition, familial hypercholesterolemia (FH), are at increased risk for atherosclerotic cardiovascular disease (ASCVD) early in life.

18 Nov 2020

Computational method could predict immunotherapy response in patients with advanced melanoma

A computational method that combines clinicodemographic variables with deep learning of pre-treatment histology images could predict response to immune checkpoint blockade among patients with advanced melanoma.

18 Nov 2020

CRYM protein counteracts the growth of prostate tumors

Prostate cancer is caused by elevated hormone levels, and tumors are generally treated using hormone therapy. However, after some time, tumor growth is no longer dependent on hormones, which results in resistance to treatment. As a result, new types of treatments are urgently needed.

18 Nov 2020

Algorithm-driven program improves cholesterol, blood pressure levels

Using a remotely-delivered, algorithm-driven program for disease management, patients experienced significant improvement in cholesterol and blood pressure levels, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2020.

18 Nov 2020

New guidelines address oxygen therapy for adults with COPD, interstitial lung disease

The latest clinical practice guideline on home oxygen therapy addresses long-term and ambulatory oxygen therapy for adults with chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD) and includes the most comprehensive review of the evidence of any oxygen guideline to date.

18 Nov 2020

Certain regions in the retina are more affected by Alzheimer's disease, shows study

A study led by the Cedars-Sinai Department of Neurosurgery has identified certain regions in the retina - the lining found in the back of the eye - that are more affected by Alzheimer's disease than other areas.

18 Nov 2020

Fatal chain reaction in Alzheimer's disease starts much earlier than commonly assumed

Alzheimer's disease develops over decades. It begins with a fatal chain reaction in which masses of misfolded beta-amyloid proteins are produced that in the end literally flood the brain.

18 Nov 2020

LOX plays a number of key roles in promoting skin and organ fibrosis in scleroderma

A team of researchers at the Medical University of South Carolina (MUSC) has found that the molecule lysyl oxidase (LOX) plays a number of important roles in promoting skin and organ fibrosis in scleroderma, a connective tissue disorder.

17 Nov 2020

Study finds more than half of in-hospital COVID-19 deaths among Black, Hispanic patients

More than half of all in-hospital deaths due to COVID-19 during the first six months of 2020 were among Black and Hispanic patients, according to a new study led by researchers at the Stanford University School of Medicine and Duke University.

17 Nov 2020

Somatic mutation may act as a natural gene therapy in patients with rare autosomal disease

Researchers affiliated with the Center for Cell-Based Therapy in Ribeirão Preto, Brazil, have identified for the first time a non-hereditary mutation in blood cells from a patient with GATA2 deficiency, a rare autosomal disease caused by inherited mutations in the gene that encodes GATA-binding protein 2 (GATA2).

17 Nov 2020

Novel patient engagement tool improved outcomes for heart failure patients

A novel patient engagement tool led one in five patients with heart failure to a more effective treatment regimen of generic medications, according to late- breaking research presented today at the American Heart Association's Scientific Sessions 2020.

17 Nov 2020

Study investigates possible link between sleep apnea and autoimmune diseases

New research by University of Georgia scientists sheds light on why people with obstructive sleep apnea may have associated autoimmune disorders. The results could lead to better approaches to treatment and possibly new drug therapies.

17 Nov 2020

Hydrogen therapy may help severely ill COVID-19 patients

Researchers from the Department of Critical Care Medicine, Sichuan Provincial People's Hospital, Chengdu in China, have explored the possibility of using hydrogen therapy on severely ill COVID-19 patients. The team published their study's findings, titled "Hydrogen: A Potential New Adjuvant Therapy for COVID-19 Patients," in the latest issue of the journal Frontiers in Pharmacology.

17 Nov 2020

Researchers report encouraging results from in vitro combination therapy against COVID-19

Researchers at Karolinska Institutet in Sweden report promising results from an in vitro combination therapy against COVID-19.

17 Nov 2020

Discovery of 'Achilles heel' in protein crucial to HIV virulence could lead to new class of drugs

The discovery of a potential "Achilles heel" in Nef, the protein that is crucial to HIV virulence and its capacity to trigger AIDS, paves the way for the development of a new class of drugs against the virus.

17 Nov 2020

Researchers identify two key biomarkers contributing to gastric cancer metastasis

A research team led by Professor Wang Wen-ching of the Institute of Molecular and Cellular Biology, National Tsing Hua University has exploited the power of big data to identify two key biomarkers contributing to the proliferation and metastasis of gastric (stomach) cancer.

17 Nov 2020

First-ever phase 3 advanced anal cancer trial opens for patient enrollment

The first randomized phase 3 clinical trial ever to be conducted in patients with advanced cancer of the anal canal is now open and enrolling patients.

16 Nov 2020

Therapy News and Research

OU College of Medicine, US Department of Defense to address problematic sexual behavior of youth

NIH project aims to maximize efficiency of AAV platform for gene therapy

Immunotherapies effective against lung cancer, melanoma may also work against rare skin tumor

New data highlights the gaps in care for children with familial hypercholesterolemia

Computational method could predict immunotherapy response in patients with advanced melanoma

CRYM protein counteracts the growth of prostate tumors

Algorithm-driven program improves cholesterol, blood pressure levels

New guidelines address oxygen therapy for adults with COPD, interstitial lung disease

Certain regions in the retina are more affected by Alzheimer's disease, shows study

Fatal chain reaction in Alzheimer's disease starts much earlier than commonly assumed

LOX plays a number of key roles in promoting skin and organ fibrosis in scleroderma

Study finds more than half of in-hospital COVID-19 deaths among Black, Hispanic patients

Somatic mutation may act as a natural gene therapy in patients with rare autosomal disease

Novel patient engagement tool improved outcomes for heart failure patients

Study investigates possible link between sleep apnea and autoimmune diseases

Hydrogen therapy may help severely ill COVID-19 patients

Researchers report encouraging results from in vitro combination therapy against COVID-19

Discovery of 'Achilles heel' in protein crucial to HIV virulence could lead to new class of drugs

Researchers identify two key biomarkers contributing to gastric cancer metastasis

First-ever phase 3 advanced anal cancer trial opens for patient enrollment

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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