Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Further Reading

CRISPR genome-editing technology can be used as a tool to discover RNA therapeutics for lung cancer

CRISPR genome-editing technology can be used as a tool to discover RNA therapeutics for lung cancer

An international team of scientists have demonstrated for the first time that CRISPR genome-editing technology can be used as a tool to find new gene therapies for lung cancer.

24 Aug 2022

Researchers identify a potential new therapeutic approach to fight angioimmunoblastic T-cell lymphoma

Researchers identify a potential new therapeutic approach to fight angioimmunoblastic T-cell lymphoma

A type of blood cell cancer called angioimmunoblastic T-cell lymphoma (AITL) can develop as mutations accumulate with age in the stem cells from which the T cells in the blood develop.

24 Aug 2022

Researchers create novel mouse model for mapping protein communication between organs

Researchers create novel mouse model for mapping protein communication between organs

Our many different organ systems are in constant communication with each other. During exercise, for example, muscles send out signals to fat and liver tissue to release their energy sources.

17 Aug 2022

Peter Adams and Bing Ren receive NIH grant to join multi-institution initiative studying the aging process

Peter Adams and Bing Ren receive NIH grant to join multi-institution initiative studying the aging process

Peter Adams, Ph.D., and Bing Ren, Ph.D., have been awarded a new grant from the National Institutes of Health (NIH) to join a multi-institution initiative studying the process of aging.

16 Aug 2022

Inventia Life Science Accelerates Growth with AU$35 million Series B Led by Blackbird Ventures, Launching 3D Cell Culture Platform into US Market

Inventia Life Science Accelerates Growth with AU$35 million Series B Led by Blackbird Ventures, Launching 3D Cell Culture Platform into US Market

Company aims to democratise access to affordable biomedical research especially in cancer research and new drug development through its novel 3D cell culture platform.

From Inventia Life Science 16 Aug 2022

Australian company accelerating the speed of drug discovery wins prestigious Eureka prize

Australian company accelerating the speed of drug discovery wins prestigious Eureka prize

Inventia Life Science announced that its RASTRUM™ 3D cell culture platform has won the ANSTO Eureka Prize for Innovative Use of Technology at the 2021 Australian Museum Eureka Prizes.

From Inventia Life Science 16 Aug 2022

Inventia Life Science partners with Xylyx Bio to develop tissue-specific, digitally-printed bioinks for drug discovery

Inventia Life Science partners with Xylyx Bio to develop tissue-specific, digitally-printed bioinks for drug discovery

Inventia Life Science and Xylyx Bio today announced their strategic partnership following promising results developing more realistic, scalable, and reproducible 3D cell cultures for drug discovery and biomedical research.

From Inventia Life Science 16 Aug 2022

Inventia Life Science Announces Partnership with PhenoVista Biosciences to Accelerate Preclinical Research with 3D Cell Models

Inventia Life Science Announces Partnership with PhenoVista Biosciences to Accelerate Preclinical Research with 3D Cell Models

Inventia Life Science, a leader in automated generation of complex 3D cell models, and PhenoVista Biosciences, a top provider of custom imaging-based phenotypic assay services, have entered into a partnership to deliver high-content cell-based assay services for drug discovery.

From Inventia Life Science 16 Aug 2022

RASTRUM™ - the 3D Printer of Living Cells, Honored in Annual Awards by Leading Business Magazine

RASTRUM™ - the 3D Printer of Living Cells, Honored in Annual Awards by Leading Business Magazine

RASTRUM™ has taken out the top prize in the Experimental category. RASTRUM™ prints human cells into living tissue models to supercharge research into cancer and other diseases using revolutionary drop-on-demand technology.

From Inventia Life Science 16 Aug 2022

Big pharma went all in to kill drug pricing negotiations

Big pharma went all in to kill drug pricing negotiations

For decades, the drug industry has yelled bloody murder each time Congress considered a regulatory measure that threatened its profits.

12 Aug 2022

UIC focuses on developing an antiviral therapy for filoviruses

UIC focuses on developing an antiviral therapy for filoviruses

Researchers at the University of Illinois Chicago are working with the National Institutes of Health and researchers from across the country to establish a center for antiviral drug development for pandemic-level viruses, including Ebola and SARS-CoV-2, the virus that causes COVID-19.

11 Aug 2022

Scripps, UCLA chemists develop a 'molecular editing' toolkit for modifying bicyclic aza-arenes

Scripps, UCLA chemists develop a 'molecular editing' toolkit for modifying bicyclic aza-arenes

Chemists from Scripps Research and the University of California, Los Angeles, have developed methods for the precise, flexible modification of a broad class of chemical compounds called bicyclic aza-arenes, which are commonly used to build drug molecules.

9 Aug 2022

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

In this interview, we speak to Tom Kostrzewski, VP of Science and Technology at CN Bio, about their organ-on-a-chip product and the future of drug discovery.

From CN Bio 3 Aug 2022

Novel algorithm provides rich, detailed information on protein location and function within a cell

Novel algorithm provides rich, detailed information on protein location and function within a cell

Humans are good at looking at images and finding patterns or making comparisons. Look at a collection of dog photos, for example, and you can sort them by color, by ear size, by face shape, and so on. But could you compare them quantitatively? And perhaps more intriguingly, could a machine extract meaningful information from images that humans can't?

2 Aug 2022

Timothy Huang receives $2.8 million to continue research on Alzheimer's disease

Timothy Huang receives $2.8 million to continue research on Alzheimer's disease

Timothy Huang, Ph.D., has been awarded $2.8 million by the National Institute on Aging (NIA) to continue his work on Alzheimer's disease.

2 Aug 2022

How does COVID-19 affect sexual and bladder functions in men?

How does COVID-19 affect sexual and bladder functions in men?

Researchers discuss the impact of COVID-19 on the urogenital health of males.

1 Aug 2022

ALZ-NET: First data collection and sharing network for new FDA-approved Alzheimer's treatments

ALZ-NET: First data collection and sharing network for new FDA-approved Alzheimer's treatments

ALZ-NET is the first network developed specifically for new FDA-approved Alzheimer's treatments, collecting real-world evidence on drug effectiveness and side effects over a long period of time.

1 Aug 2022

The recent progress in investigating the inhibitory impact of nanosponges and antiviral delivery against SARS-CoV-2

The recent progress in investigating the inhibitory impact of nanosponges and antiviral delivery against SARS-CoV-2

Researchers assessed the potential of nanosponges against SARS-CoV-2.

1 Aug 2022

Researchers use a tumor organoid system to examine bacterial effects on immunotherapy

Researchers use a tumor organoid system to examine bacterial effects on immunotherapy

Wake Forest Institute for Regenerative Medicine researchers are using a tumor organoid system to examine the effects of metabolites secreted by bacteria on a specialized immunotherapy – immune checkpoint blockage, a promising cancer treatment development – to determine why some patients don't respond or develop a resistance to the treatment over time.

29 Jul 2022

Study uncovers the crucial roles of kinesins during the malaria parasite life cycle

Study uncovers the crucial roles of kinesins during the malaria parasite life cycle

Scientists at the University of Nottingham have made a major breakthrough in understanding how malaria parasites divide and transmit the disease, which could be a major step forwards in helping to prevent one of the biggest killer infections in the world.

29 Jul 2022

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