Hematology News and Research

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Hematology, also spelled haematology, is the branch of biology (physiology), pathology, clinical laboratory, internal medicine, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases. Hematology includes the study of etiology, diagnosis, treatment, prognosis, and prevention of blood diseases.

Child life services serve as major component of pediatric hospital-based care

Being in the hospital is no bed of roses. Especially for kids. "For many children, the hospital can be a scary place," said Linda Nicolotti, Ph.D., director of pediatric psychology at Brenner Children's Hospital, part of Wake Forest Baptist Medical Center.

20 Dec 2017

Scientists develop test to predict treatment outcomes in patients with childhood leukemia

UC San Francisco physician-scientists have developed a test that can predict how patients with juvenile myelomonocytic leukemia (JMML) will respond to treatment, and may also be able to identify patients who are likely to recover spontaneously with little to no treatment.

19 Dec 2017

Study provides insights on factors that affect quality of life in older cancer patients

A new study provides insights on the factors that affect health-related quality of life in older adults with cancer. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings support the importance of addressing persistent symptoms, managing comorbidities, promoting leisure-time physical activity, and addressing financial challenges.

18 Dec 2017

Transfusion dependence reduces access to high-quality end-of-life care for leukemia patients

For patients with advanced leukemia, access to high-quality end-of-life care appears to be reduced in those dependent on blood transfusions, according to a new study being presented during the 59th American Society of Hematology Annual Meeting and Exposition in Atlanta.

13 Dec 2017

Mayo Clinic study: Increasing physical activity decreases risk of death from lymphoma

An observational study by researchers at Mayo Clinic has found that increasing physical activity not only decreased the risk of death from all causes but also decreased the risk of death specifically from lymphoma.

13 Dec 2017

Caris Life Sciences reveals identification of new mechanism of action to treat NHL

Caris Life Sciences, a leading innovator in molecular science focused on fulfilling the promise of precision medicine, today announced a data presentation, at the 59th American Society of Hematology Annual Meeting & Exposition in Atlanta, demonstrating the identification of a new mechanism of action to treat non-Hodgkin lymphoma (NHL).

13 Dec 2017

FDA researchers find underrepresentation of adults aged 75 years and older in blood cancer clinical trials

In the first comprehensive analysis of clinical trial enrollment among older adults with blood cancers, researchers from the U.S. Food and Drug Administration found significant gaps in participation among those aged 75 and older when considered against the incidence of these malignancies in this age group, according to research being presented today during the 59th American Society of Hematology Annual Meeting and Exposition in Atlanta.

12 Dec 2017

Study: Combination targeted therapy has high response rates in AML patients

Initial findings from a multi-national open-label phase Ib study of inhibitory drug therapy for relapsed or refractory acute myeloid leukemia (AML) have demonstrated a complete response in up to 50 percent patients say researchers at The University of Texas MD Anderson Cancer Center.

11 Dec 2017

New, more easily administered therapies offer benefits for bleeding and clotting disorders

In three studies being presented today during the 59th American Society of Hematology (ASH) Annual Meeting and Exposition in Atlanta, researchers report remarkable benefits from new, more easily administered therapies for bleeding and clotting disorders.

11 Dec 2017

Scientists develop software that predicts leukemia-specific immune targets

University of North Carolina Lineberger Comprehensive Cancer Center scientists have developed a software program that can accurately predict which tumor-specific markers will show up on the surface of leukemia cells in patients who have received stem cell transplants.

11 Dec 2017

Pairing immunotherapy drug with chemotherapy proves beneficial for relapsed acute myeloid leukemia

University of North Carolina Lineberger Comprehensive Cancer Center researchers report that pairing an immunotherapy drug with chemotherapy proved beneficial for some patients with acute myeloid leukemia whose disease did not respond to standard treatment or had relapsed.

11 Dec 2017

Combination of chemotherapy and targeted drug improves response in younger CLL patients

Among younger patients newly diagnosed with chronic lymphocytic leukemia (CLL), treatment with a combination of chemotherapy and a molecularly targeted drug significantly improves response over what is typically seen with chemotherapy alone, according to an investigator-initiated multi-center phase II clinical trial.

11 Dec 2017

Mayo Clinic researchers find emojis to be helpful in assessing patients' quality of life

In findings presented to the American Society of Hematology, Mayo Clinic researchers found that using emojis instead of traditional emotional scales were helpful in assessing patients' physical, emotional and overall quality of life.

11 Dec 2017

St. Jude gene therapy offers hope for infants with 'bubble boy' disease

Early evidence suggests that gene therapy developed at St. Jude Children's Research Hospital will lead to broad protection for infants with the devastating immune disorder X-linked severe combined immunodeficiency disorder.

11 Dec 2017

New genetic model identified for predicting outcomes in patients with primary myelofibrosis

A group of investigators from Mayo Clinic and multiple academic research centers in Italy have identified a genetic model for predicting outcomes in patients with primary myelofibrosis who are 70 years or younger and candidates for stem cell transplant to treat their disease.

11 Dec 2017

CAR T cell therapy shows long-lasting remissions in non-Hodgkin's lymphoma patients

In a pair of clinical trials stretching from Philadelphia to Tokyo, the chimeric antigen receptor (CAR) T cell therapy Kymriah (formerly known as CTL019) demonstrated long-lasting remissions in non-Hodgkin's lymphoma (NHL) patients.

11 Dec 2017

Drug improves disease-free, overall survival after hematopoietic stem cell transplants

Results from a phase 2 clinical trial, presented by Seattle Children's Research Institute at the 59th American Society of Hematology Annual Meeting, show that the drug Abatacept (Orencia) nearly eliminated life-threatening severe acute graft-versus-host disease (GvHD) in patients receiving hematopoietic stem cell transplants.

11 Dec 2017

Two immunotherapy approaches for multiple myeloma show hope

Researchers from the University of Pennsylvania's Abramson Cancer Center have developed two experimental immunotherapy methods that include one chimeric antigen receptor (CAR) T cell therapy for the treatment of multiple myeloma patients who were not responding to other treatments.

11 Dec 2017

Gene therapy shows promising effect against blood clots, study states

A new study conducted in the Children's Hospital Of Philadelphia (CHOP) reported positive results in a phase 1/2 clinical trial for the inherited bleeding disorder hemophilia B.

8 Dec 2017

Australian researchers develop new risk scoring system to predict childhood leukemia relapse

Australian researchers have developed a new risk scoring system for children with leukemia based on missing DNA fragments or 'microdeletions'.

1 Dec 2017

Hematology News and Research

Further Reading

Child life services serve as major component of pediatric hospital-based care

Scientists develop test to predict treatment outcomes in patients with childhood leukemia

Study provides insights on factors that affect quality of life in older cancer patients

Transfusion dependence reduces access to high-quality end-of-life care for leukemia patients

Mayo Clinic study: Increasing physical activity decreases risk of death from lymphoma

Caris Life Sciences reveals identification of new mechanism of action to treat NHL

FDA researchers find underrepresentation of adults aged 75 years and older in blood cancer clinical trials

Study: Combination targeted therapy has high response rates in AML patients

New, more easily administered therapies offer benefits for bleeding and clotting disorders

Scientists develop software that predicts leukemia-specific immune targets

Pairing immunotherapy drug with chemotherapy proves beneficial for relapsed acute myeloid leukemia

Combination of chemotherapy and targeted drug improves response in younger CLL patients

Mayo Clinic researchers find emojis to be helpful in assessing patients' quality of life

St. Jude gene therapy offers hope for infants with 'bubble boy' disease

New genetic model identified for predicting outcomes in patients with primary myelofibrosis

CAR T cell therapy shows long-lasting remissions in non-Hodgkin's lymphoma patients

Drug improves disease-free, overall survival after hematopoietic stem cell transplants

Two immunotherapy approaches for multiple myeloma show hope

Gene therapy shows promising effect against blood clots, study states

Australian researchers develop new risk scoring system to predict childhood leukemia relapse

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