Infectious Diseases News and Research

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Ubiquigent and Debiopharm enter agreement to support USP1 inhibitor programme for Debio 0432

Project will be a demonstration of how Ubiquigent’s DUB-centric platform can support the development of DUB inhibitors all the way from discovery through to clinical development.

From Ubiquigent Limited 26 Mar 2024

Redefining tuberculosis classification to enhance early detection and treatment

A new way to classify tuberculosis (TB) that aims to improve focus on the early stages of the disease has been launched by an international team including researchers from the London School of Hygiene and Tropical Medicine (LSHTM).

26 Mar 2024

Global fight against TB misses 2020 WHO milestones, despite progress in certain age groups

The global, national, and regional burden and trends in tuberculosis.

26 Mar 2024

New method predicts sepsis and organ failure in children

University of Queensland researchers have developed a method to predict if a child is likely to develop sepsis and go into organ failure.

25 Mar 2024

Leveraging cancer therapies to combat tuberculosis

What could cancer teach us about tuberculosis? That's a question Meenal Datta has been chasing since she was a graduate student.

25 Mar 2024

UVA researchers develop online tool to combat childhood diarrheal diseases

University of Virginia researchers are developing a flexible online tool for navigating information used in the fight to save children from deadly diarrheal diseases by identifying transmission hotspots and accelerating the deployment of treatments and new vaccines.

25 Mar 2024

UQ researchers use new dosing technology to enhance ICU antibiotic treatment

University of Queensland researchers have used dosing software to accelerate the effects of antibiotics in patients being treated for sepsis in Intensive Care Units.

24 Mar 2024

Southern expansion of hemorrhagic fever virus in Sweden linked to bank voles

Researchers have discovered that bank voles in Skåne, southern Sweden, carry a virus that can cause hemorrhagic fever in humans.

22 Mar 2024

Boosting butyrate-producing gut bacteria lowers hospitalization rates for infections

A study of two large European patient cohorts has found that for every 10% increase in butyrate-producing bacteria in a patient's gut, the risk of hospitalization for any infection falls by between 14 and 25% across two large national cohorts.

22 Mar 2024

UCLA researchers develop promising vaccine against deadly melioidosis bacterium

In a mouse study, UCLA researchers tested a vaccine against the bacterium that causes melioidosis and found it was highly protective against the disease, which is endemic in many tropical areas, causing approximately 165,000 cases with 89,000 fatalities around the world each year.

22 Mar 2024

Using whole genome sequencing to identify non-culturable Legionella

Legionnaires' disease (LD), a rare and severe type of pneumonia, is a respiratory infection caused by species of Legionella bacteria.

21 Mar 2024

Study highlights global fertility decline and its implications for the future

The world is approaching a low-fertility future. Although by 2100 more than 97% of countries and territories will have fertility rates below what is necessary to sustain population size over time, comparatively high fertility rates in numerous low-income countries, predominantly in western and eastern sub-Saharan Africa, will continue to drive population increases in these locations throughout the century.

21 Mar 2024

Innovative study on asthma inflammation funded by NIH/NIAID grant

In a significant stride for respiratory medicine, Lundquist Institute (TLI) investigator Nicholas Jendzjowsky, PhD, has been awarded a prestigious grant from the National Institute of Health/National Institute of Allergy and Infectious Diseases (NIH/NIAID).

21 Mar 2024

Rapid rise in syphilis hits Native Americans hardest

From her base in Gallup, New Mexico, Melissa Wyaco supervises about two dozen public health nurses who crisscross the sprawling Navajo Nation searching for patients who have tested positive for or been exposed to a disease once nearly eradicated in the U.S.: syphilis.

21 Mar 2024

Climate change heats up fungal threats worldwide

Review in The Lancet Microbe discusses how rising global temperatures enable fungi to adapt, becoming more thermotolerant and expanding into new areas, which may lead to an increased emergence of novel pathogens impacting socially vulnerable groups the most.

20 Mar 2024

Immune cell protein identified as potential target for rare liver cancer treatment

Fibrolamellar carcinoma (FLC) is a rare liver cancer with a poor prognosis if not addressed early with surgery. The disease is caused by a single genetic mutation that creates a fusion protein.

20 Mar 2024

New drug candidates show promise to reverse HIV immune evasion

University of Pittsburgh School of Medicine scientists have identified drug candidates that show promise to reverse the ability of HIV to escape detection by the immune system.

19 Mar 2024

Health workers fear it’s profits before protection as CDC revisits airborne transmission

Four years after hospitals in New York City overflowed with covid-19 patients, emergency physician Sonya Stokes remains shaken by how unprepared and misguided the American health system was.

19 Mar 2024

Genetic key to milder COVID: Certain genes slash severity and death risk in older men

Study found that certain genetic variants in the IL1RN gene significantly reduce COVID-19-related inflammation and mortality in patients, with notable improvements observed in older men carrying specific single-nucleotide variants.

19 Mar 2024

Study uncovers how APOBEC enzymes drive cancer mutations

A research team led by the University of California, Irvine has discovered the key role that the APOBEC3A and APOBEC3B enzymes play in driving cancer mutations by modifying the DNA in tumor genomes, offering potential new targets for intervention strategies.

18 Mar 2024