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Tirzepatide cuts diabetes risk by 90% in obese patients, study shows

Tirzepatide, a new injectable weight-loss drug with the trade name Zepbound, reduced the risk of diabetes in patients with obesity and prediabetes by more than 90% over a three-year period, compared with placebo, according to the results of a new study led by investigators at Weill Cornell Medicine, NewYork-Presbyterian, Yale School of Medicine and other institutions.

26 Nov 2024

Genetic factors drive early onset and complications of type 2 diabetes in British Asians

A genetic predisposition to having lower insulin production and less healthy fat distribution are major causes of early-onset type 2 diabetes in British Asian people.

26 Nov 2024

GLP-1 receptor agonists prove effective for kidney and cardiovascular outcomes

The biggest and most comprehensive analysis of glucagon-like peptide-1 (GLP-1) receptor agonists on kidney and cardiovascular outcomes shows they have significant benefits in people with and without diabetes.

25 Nov 2024

Revolutionary strategy offers hope for type 1 diabetes treatment

Regenerative medicine holds the extraordinary promise that future patients in need of new cells, tissues or organs will no longer have to rely on donors. Organ shortages and cell type mismatches will become past problems, replaced by safe, on-demand options for anyone who needs a transplant.

25 Nov 2024

New therapy from UI Health becomes the first FDA-approved treatment for brittle type 1 diabetes

A new therapy for brittle type 1 diabetes, the only treatment currently approved by the U.S. Food and Drug Administration, is available exclusively at UI Health in Chicago.

25 Nov 2024

Severe pregnancy complications reduce likelihood of having more children

Women who suffer severe complications during their first pregnancy or delivery are less inclined to have more babies, a study published in JAMA by researchers at Karolinska Institutet reports.

25 Nov 2024

Could medical imaging innovation be the catalyst for precision medicine?

Precision medicine leverages genetic and lifestyle data to customize treatments, enhancing healthcare efficiency and patient outcomes in disease management.

24 Nov 2024

Why predictive retina models could be the future of IND applications

Discover how retina models are revolutionizing rare disease treatment and accelerating drug development.

From Newcells Biotech 22 Nov 2024

New microscopy technique enables 3D RNA analysis in intact mouse brains

Researchers at Karolinska Institutet and Karolinska University Hospital have developed a groundbreaking microscopy method that enables detailed three-dimensional (3D) RNA analysis at cellular resolution in whole intact mouse brains.

22 Nov 2024

Georgians with disabilities are still being institutionalized, despite federal oversight

Lloyd Mills was tired of being stuck in a small, drab hospital room. On a rainy mid-September morning, a small TV attached to a mostly blank white wall played silently. There was nothing in the space to cheer it up — no cards, no flowers.

22 Nov 2024

Cetuximab performs better than durvalumab in treating head and neck cancers

Head and neck cancers are the seventh most common type of cancer worldwide, according to the 2020 World Cancer Report. Smokers and drinkers, as well as those with HPV infections, are disproportionately affected.

22 Nov 2024

Fermented kimchi may help combat obesity by regulating gut microbiota

Kimchi consumption significantly reduces body fat and enhances metabolic indicators in overweight individuals, highlighting its role in obesity management.

22 Nov 2024

SCimilarity revolutionizes single-cell data analysis with rapid cross-tissue comparisons

Researchers developed SCimilarity, a groundbreaking metric-learning framework, to rapidly analyze and compare single-cell data across tissues, diseases, and experimental conditions. This tool enables scalable discovery of shared cellular states and biological insights across the Human Cell Atlas.

21 Nov 2024

UVA researchers discover how blood pressure medications affect kidneys

University of Virginia School of Medicine researchers have discovered how long-term treatment of high blood pressure with commonly prescribed drugs can destroy the kidney's ability to filter and purify blood.

21 Nov 2024

Electrical stimulation of vagus nerve could combat inflammatory bowel disease

Researchers at Duke University School of Medicine have found that tapping into the nervous system could help reduce the gut inflammation that drives inflammatory bowel disease (IBD).

20 Nov 2024

Decoding the genetic roots of stroke and heart attack

In a new study published in the European Heart Journal, researchers at Karolinska Institutet show that genetic traits influence the cellular composition of atherosclerotic plaques, which over time will affect the risk of such lesions to cause a stroke or heart attack. The new knowledge can be used to improve the risk assessment and treatment of patients with atherosclerosis in the future.

20 Nov 2024

More than half of all US adults are eligible for semaglutide therapy

Over 137 million US adults are eligible for semaglutide, driven by expanding indications for diabetes, weight management, and cardiovascular disease prevention.

20 Nov 2024

Diabetes drugs cut asthma attacks by up to 70%, reshaping treatment options

Metformin and GLP-1 receptor agonists significantly reduce asthma attacks in patients with type 2 diabetes, offering potential new treatments for asthma.

19 Nov 2024

New cell model reveals how hepatitis E viruses affect nerve cells

Using a new cell model, researchers can for the first time study how hepatitis E viruses affect nerve cells.

19 Nov 2024

New nasal spray form of bumetanide shows promise for heart failure treatment

A new nasal spray form of the medication bumetanide may reduce the tissue swelling caused by heart failure as effectively as the standard oral and intravenous formulations of the medication, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

19 Nov 2024