Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

The gut shields the liver from fructose-induced lipogenesis

After one consumes food or a beverage containing fructose, the gastrointestinal system, or gut, helps to shield the liver from damage by breaking down the sugar before it reaches the liver, according to a new multi-center study led by researchers in the Perelman School of Medicine at the University of Pennsylvania.

29 Jun 2020

Review highlights why and to what extent a large hip protects from type 2 diabetes and CVD

In a Lancet Diabetes & Endocrinology review article Norbert Stefan from the German Center for Diabetes Research, the University Hospital of Tübingen and the Boston Children's Hospital, highlights why and to what extent a large hip circumference, an estimate of increased fat mass in the lower part of the body, protects from type 2 diabetes and cardiovascular diseases.

18 Jun 2020

Study investigates effectiveness of liver perfusion to improve the function of donor livers

A major study investigating the effectiveness of liver perfusion as a technique to improve the function of donor livers that would have otherwise been rejected has shown that up to 7 in every 10 could be used after just 4-6 hours of the assessment.

17 Jun 2020

Even brief exposure to certain chemicals can prematurely age the liver epigenome

The epigenome is sometimes referred to as the "software" or "operating system" of the genome. It comprises small chemical modifications to DNA and the proteins that make up our chromosomes, and controls the activity of all the genes within the genome.

17 Jun 2020

Novel antisense drug shows promise to improve health of people with NAFLD

Using a first-of-its-class drug in a clinical trial, an international research effort headed by a scientist at University of California San Diego School of Medicine reports that inhibition of a key enzyme safely and effectively improved the health of persons with non-alcoholic fatty liver disease, a chronic metabolic disorder that affects hundreds of millions of people worldwide.

16 Jun 2020

Creating the first 3D neural map of a heart

News-Medical spoke to Dr. Vadigepalli and Dr. Schwaber about their groundbreaking research in which they managed to map the neurons in the heart.

15 Jun 2020

Researchers explore amino acids for a new diet approach

A new diet approach that restricts essential amino acids was explored in new research by a team of international scientists from Australia, Denmark, and Germany.

11 Jun 2020

Scientists develop new test to help identify people at risk for developing liver cancer

Scientists have developed a new test that can help identify people who are likely to develop hepatocellular carcinoma (HCC), the most common form of liver cancer. The approach uses a simple blood test to check for the patient's previous exposure to certain viruses.

11 Jun 2020

BAM15 could be an effective drug for treating obesity and related diseases

A new study offers the first evidence that a protein named BAM15 acts as an energy uncoupler and could be an effective drug for treating obesity and related diseases.

10 Jun 2020

Study provides new evidence that liver dysfunction may lead to heart disease

A new study that looks closely at the cardiac health of flies provides new evidence that liver dysfunction may lead to deterioration of the heart.

10 Jun 2020

Research team provides new insights on the communication between liver and brain

A research team in Vienna is investigating how calorie intake, liver activity and fat storage interact and what role the central nervous system plays in this.

10 Jun 2020

Research demonstrates novel pathway regulating the underlying mechanism of NASH

CN Bio, a leading cell culture company that has developed single and multi-organ microphysiological systems that improve the accuracy and efficiency of drug discovery, today announced the publication of co-authored research led by researchers at the University of Cambridge in Nature Metabolism, identifying a novel pathway that regulates the underlying mechanism of Non-Alcoholic Steatohepatitis, potentially a new therapeutic target.

10 Jun 2020

Fecal transplants could be used as treatment for non-alcoholic fatty liver disease

A new study from Lawson Health Research Institute and Western University suggests that fecal transplants could be used as a treatment for non-alcoholic fatty liver disease.

9 Jun 2020

Virginia Tech researcher develops new ‘fat burning’ molecule with potential to treat obesity

Obesity affects more than 40 percent of adults in the United States and 13 percent of the global population.

8 Jun 2020

MUSC receives $16.5 million NIH funding to open two new digestive disease research centers

This spring marked a seismic shift for digestive and liver disease research at the Medical University of South Carolina with the award of more than $16.5 million in National Institutes of Health funding to open two new tightly integrated centers.

5 Jun 2020

Study shows women are less susceptible to cirrhosis-related deaths

Prior studies have suggested women might have higher mortality of cirrhosis of the liver than men. Women are also less likely to receive liver transplantation.

5 Jun 2020

Newly identified mechanism regulates activity of nitric oxide-producing enzyme

The liver filters blood, detoxifies chemicals and metabolizes drugs. Hepatitis, alcohol and primary liver diseases are common sources of damage in the liver and can result in scarring, known as fibrosis.

5 Jun 2020

New insights into how parenteral oil emulsions prevent liver disease in preterm babies

Infants born prematurely may require parenteral or intravenous nutrition to provide the necessary nourishment, as their digestive system is immature and cannot digest nutrients.

4 Jun 2020

Cases of alcohol-related liver disease will rise dramatically in coming years, shows study

Alcohol-related liver disease is currently the most common reason for liver transplantation in the United States. In recent years, high-risk drinking of alcohol--defined as exceeding daily drinking limits (more than 4 or 5 standard drinks for women and men, respectively) at least weekly for a whole year--has increased in nearly all sociodemographic groups, especially in women.

4 Jun 2020

Study shows Sofosbuvir alleviates COVID-19-related neurological symptoms

A group of researchers has studied the effects of an antiviral drug Sofosbuvir on human brain organoids infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

2 Jun 2020

Liver Disease News and Research

Further Reading

The gut shields the liver from fructose-induced lipogenesis

Review highlights why and to what extent a large hip protects from type 2 diabetes and CVD

Study investigates effectiveness of liver perfusion to improve the function of donor livers

Even brief exposure to certain chemicals can prematurely age the liver epigenome

Novel antisense drug shows promise to improve health of people with NAFLD

Creating the first 3D neural map of a heart

Researchers explore amino acids for a new diet approach

Scientists develop new test to help identify people at risk for developing liver cancer

BAM15 could be an effective drug for treating obesity and related diseases

Study provides new evidence that liver dysfunction may lead to heart disease

Research team provides new insights on the communication between liver and brain

Research demonstrates novel pathway regulating the underlying mechanism of NASH

Fecal transplants could be used as treatment for non-alcoholic fatty liver disease

Virginia Tech researcher develops new ‘fat burning’ molecule with potential to treat obesity

MUSC receives $16.5 million NIH funding to open two new digestive disease research centers

Study shows women are less susceptible to cirrhosis-related deaths

Newly identified mechanism regulates activity of nitric oxide-producing enzyme

New insights into how parenteral oil emulsions prevent liver disease in preterm babies

Cases of alcohol-related liver disease will rise dramatically in coming years, shows study

Study shows Sofosbuvir alleviates COVID-19-related neurological symptoms

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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